Weariness Diagnosis System

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Weariness Diagnosis System

• Portable Medical System
• from
• Moscow State University

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Moscow State University team

• Faculty mentor prof. V. P. Ivannikov
• mentors assistant A. Chernov
• Team members
• P. Iakovenko
• A. Khokhlov
• A. Petrov
• D. Vassioura

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Contents

• Purpose and use of the system
• Theoretical foundations
• Architecture overview
• Conclusions

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Purpose of the system

• Provide a mean for real-time diagnostics based on
  heart rate
• Provide a facility for long-term data storage
• Allow a doctor reporting a new diagnosis to the
  patient
• Allow easy extension of the system with new
  diagnostics methods

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Areas of application

• Human safety-related professions (pilots,
  drivers, etc)
• Risk groups (myocardial infarction, etc)
• General public as health self-monitoring appliance

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Theoretical foundations

• Mathematical analysis of cardiac rhythm - a way
  to examine functional condition of an organism
• Two-circuit model of cardiac rhythm control by
  Baevsky R.M.
• Characteristics of regulation systems
• Measurement of showings for the certain
  characteristics

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Theoretical foundations (cont.)

• The regulatory system activity showing (RSAS) -
  the integral value
• Medical interpretation of RSAS

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Medical works used

• Parin V.V., Baevsky R.M., Introduction to
  medical cybernetics. Moscow Praga, 1966
• Baevsky R.M., Kirillov O.I., Kletskin S.M.
  Mathematical analysis of cardiac rhythm
  variation at stress. Moscow Science, 1984
• Baevsky R.M., Berseneva A.P., Estimation of
  adaptable opportunities of an organism and risk
  of development of diseases. Moscow Medicine,
  1997

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Cardiac intervals (R-R intervals)
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Two-circuit model by Baevsky
Regulatory system
Level A - organism reorganization due to
environmental factors
Environment
Level B - regulation of interaction between
different systems
Level C - parameter aligning inside certain
systems
NC
S
V
HC
Sinus node
Autonomous system
S, V, NC, HC - nervous control channels
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Cardiac rhythm analysis methods
Analysis of average, transitional and instant
values of heartbeat frequency
Heart rate variability analysis
Cardiac rhythm trend analysis
Statistical analysis
Variation analysis
Correlation analysis
Spectral analysis
Evaluation of Regulator Systems condition
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The characteristics of cardiac rhythm regulation
systems

• Overall regulation function
• Myocardial automatism function
• Vegetative homeostasis function
• Stability of regulation function
• Subcorcial nervous centers activity function

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Showing 1 the overall regulation function
Statistical analysis
Heartbeat frequency
Mean value
The overall regulation function
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Physiological interpretation of showing 1 (ORF)
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Showing 2 the myocardial automatism function
Statistical analysis
Variation analysis
Root-mean-square deviation
Variation coefficient
Variation amplitude
Myocardial automatism function
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Showing 3 the vegetative homeostasis function
Variation analysis
Variation amplitude
Mode amplitude
Tension index
Vegetative homeostasis function
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Showing 4 stability of regulation
Statistical analysis
Variation analysis
Correlation analysis
Variation coefficient
Mean value
Tension index
Correlation coefficient after the first shift
Number of shifts before the first negative
correlation coefficient
Stability of regulation function
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Showing 5 SNC activity
Spectral analysis
The energy of respiratory waves
The energy of slow waves
The energy of the spectrum in the zero point
Subcorcial nervous centers (SNC) activity function
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RSAS - the integral value
The overall regulation function
The myocardial automatism function
The vegetative homeostasis function
Subcorcial nervous centers activity
Stability of regulation
The regulatory system activity showing
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Scale for condition evaluation
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Detailed description of RSAS scale

• Normal
• Minimal (or optimal) tension of regulation
  systems - satisfactory adaptation to
  environmental factors
• Functional tension
• Mobilization of organism protective systems
• Overwork condition
• Incapability of adaptation systems to provide
  optimal reaction to environmental factors
• Emaciation condition
• First symptoms of disease may occur

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System overview

• Three tier architecture
• 1st tier - RDBMS (MySQL)
• 2nd tier - Data exchange server
• 3rd tier - Clients handheld, administrative,
  doctor assistant

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System architecture diagram
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Exchange server functions

• Database access
• User authorization access control
• Messages diagnostics storage and exchange

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Server implementation

• Java daemon application
• Multi - threaded server for parallel client
  communication data management
• Extendable object-based server protocol

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Current server implementation

• Server is now running on
• Pentium III 450MHz
• 64 MB RAM
• 4GB HDD
• MySQL serves as a database management system

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Server requirements

• Desktop computer
• Java runtime environment
• Database access through JDBC
• Permanent Internet connection

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Portable client functions

• Real-time data collection filtering
• Temporal storage for data
• Real-time evaluations
• Evaluation results display
• Visual and sound alarm
• Regular data uploading to server

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Client implementation

• Lightweight Java application
• Multi - threaded for parallel data collection and
  real-time processing
• Establishes only temporary Internet connection
  for data transfer
• Pulse sensor as a kernel module

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Current client implementation

• Carriers client is working on
• AMD K6-2 333MHz
• 32 MB RAM
• 8 MB Flash ROM
• 160 MB PCMCIA hard drive
• Pulse sensor device attached to a COM port

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Client requirements

• Minimal hardware requirements
• Pentium class processor
• 32 MB RAM
• 16 MB Flash ROM
• Minimal Java runtime environment
• Internet connection (periodically)
• Some visual audio capabilities

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Add-ons overview

• Administrative GUI
• Doctor assistant
• Extendable via new clients
• Extendable via new data evaluation classes

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Future... What is to be done?

• Small handheld or wearable device implementation
• Develop data filtering methods
• Extended data analysis methods and classes
• Embedded Java client platform