of an intimate rhythm and chronic a bronchitis

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Heart rate variability and chronic obstructive
bronchitis
Y. N. Pasko, M. I. Yabluchansky Kharkiv National
University named by V.N. Karazin
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Heart rate variability

• Provide a method of the control and condition of
  regulation of organisms systems
• HRV is the tool of rating regulation of disorders
  by different diseases

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Chronic obstructive bronchitis

• Desease, in mechanisms and manifestations of
  which an important role belongs to disorders of
  systems regulation
• The HRV method is tested at chronic obstructive
  bronchitis (COB) and showed its the diagnostic
  importance
• The correlation in HRV parameters and degree of
  weight COB was not studied

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The research purpose

• To establish possible connection of parameters
  HRV with a degree of weight COB for increasing of
  diagnostics quality and efficiency of therapy of
  disease

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The researched contingent

• 21 patients with an average and heavy degree of
  weight COB
• 14 patients of an average degree of weight COB
• 7 patients of a heavy degree of weight COB
• Age researched 52 5 years
• Duration COB 7,8 2,3 years

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The researched contingent

• Criteria of inclusion
• Primary COB
• Age 20-65 years
• Changes by spirometry
• Changes on radiograph (emphysema)
• The complaints (breathlessness, cough)
• The long experience of the smoker

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The researched contingent

• Criteria of exception

• Age lt 20 up to gt 65
• Other diseases of respiratory system
• asthma
• ?uberculosis
• cancer lungs

• Occupational diseases
• Cardiovascular pathology
• Diffuse systemic diseases of a connecting tissue
• Gastrointestinal diseases
• Diseases of kidneys

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Design of research
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Respiratory criteria distributing by investigated
groups
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Investigated parameters of heart rate variability
VLF
LF
HF
TF - a total frequency VLF - a very low
frequency LF - a low frequency HF - ahigh
frequency
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Technology of research heart rate variability

• 12 hours prior to research were cancelled
• Medicines
• Coffee
• Alcohol
• The analysis of data was processed with the help
  of diagnostic system "Cardiolab-2000"

• The 5-minute intervals electrocardiography were
  investigated
• The measurements were executed in two positions
• In rest
• In at orthostasis

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Structure of HRV spectrum in groups COB in rest
TP and all its components increasing in
rest authentically higher in the first group of
the patients The LF/HF relation is much higher
in the second group of the patients
Group 1
Group 2
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Structure of HRV spectrum in groups COB in active
test
In rest group 1
The reaction in at orthostasis in both groups of
the patients is shown by decrease ?? in all
frequency ranges, HF range decreasing rate is
more markable
In at orthostasis group 1
In rest group 2
In at orthostasis group 2
HF LF TP
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Variation LF/HF in subgroups COB in active test
In rest group 1
Increasing of LF/HF in at orthostasis at the
expense contribution LF, in rest higher values
of parameter in group 2, and stronger reaction
in active test in group 1
In at orthostasis group 1
In rest group 2
In at orthostasis group 2
1 gr 2 gr
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Conclusions

• There is a certain mutual relation between weight
  COB and changes of parameters HRV
• COB of heavy degree differentiate by lower ?? and
  capacity all its components
• COB of average degree of weight differentiate by
  higher ?? and capacity all its components
• The correlation LF/HF initially is higher and
  also is characterized by smaller orthostatic
  growth by COB heavy in comparison with COB of
  average degree of weight
• The reaction at orthostasis by COB of heavy and
  average degree of weight is qualitatively
  adequate and also is shown by decrease ?? in all
  frequency ranges with increase of the relative
  contribution LF and increase LF\HF, however is
  quantatively deficiently by COB of a heavy degree
• The existence of correlations in weight COB and
  parameters HRV is the good basis for continuing
  of research and search on its basis of new
  methods of diagnostics, prediction and increase
  of efficiency of COB therapy