Ectoderm

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Ectoderm

• The conditional specification, determination, and
  differentiation of the neural tube, the neural
  crest, and the epidermis.

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Hinge points medial
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Hinge points dorsolateral
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Morphogenetic forces

• Neural plate cells become columnar

• Bending at the MHP where cells anchored to the
  notochord become wedge shaped
• Bending at the DLHP where cells anchored to
  epidermis become wedge shaped
• Pushing by epidermis
• Closure (sorting out)

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Inject early cells from one side with N-cadherin
mRNA
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Folate receptors
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See Figure 9.2 of Wright, p. 131.
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Dorsal root (sensory) Dorsal root
ganglion Motor horn of spinal cord Ventral root
(motor) Spinal nerve
Dorsal induced by epidermis
Ventral induced by notochord
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Reflex arc
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Lens with developing cataract
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D
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Instructional induction