Introduction to Bio-Informatics

1
Introduction to Bio-Informatics
2
Bio-Informatics

• mid-1980s analysis of biological sequence data
• Lately the computer applications in biological
  sciences

3
Protein

• Http//www.rcsb.org/
• Search for PBD id 1tfd
• 3D structure
• a.a. sequence

4
DNA

• National Center for Biotechnology Information
  (NCBI)
• http//www.ncbi.nlm.nih.gov/Sitemap/index.html
• Mapping
• Gene expression - Functional genomics
• Sequence
• Artificial Chromosome
• Yeast Artificial Chromosome
• Bacteria Artificial Chromosome

5
Homework

• Molecular primer
• http//www.ncbi.nlm.nih.gov/About/primer/index.htm
  l
• Human genome project tour
• http//www.ncbi.nlm.nih.gov/Tour/