Proximal Convoluted PowerPoint PPT Presentation

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Title: Proximal Convoluted


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Distal Convoluted Tubule
Proximal Convoluted Tubule
Descending Loop of Henle
Collecting Duct
Ascending Loop of Henle
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This basolateral Na/K ATPase serves as
driving force for Na reabsorbtion
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Water then follows the Na from apical to
basolateral side. Driving force for water
reabsorption is osmotic.
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Glucose re- absorption is by glucose/Na
symporter. Driving force is also Na gradient.
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Loop diuretics block this transporter
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Thiazide diuretics block this transporter
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CCD Na/K ATPase is activated by aldosterone which
causes increased Na reabsorption increased
water reabsorption and increased volume/BP
Preferred path of K secretion
aldosterone
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