PREVALENCE OF HIV INFECTION IN RURAL FREE STATE

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PREVALENCE OF HIV INFECTION IN RURAL FREE STATE
Van Wyk H.J., Groenewald A.J., Walsh C.M., Van
Zyl S., Van der Merwe L.J., Departments of
Chemical Pathology, Human Nutrition and Basic
Medical Sciences, Faculty of Health Sciences,
UFS
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Introduction

• HIV Prevalence (National community-based survey,
  2004, n8438)
• National prevalence 11.4
• Gender female 12.8, male 9.5
• Race blacks 12.9, whites 6.2, coloureds 6.1,
  Indians 1.6
• Informal urban areas 21.6
• Peak prevalence woman 20-29 years (24.1), men
  30-39 years (21.3)
• Free State 14.9

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Introduction

• HIV prevalence for 2006 on antenatal clinic
  attendees,
• Department of Health, 2007
• National prevalence (29.1)
• Peak prevalence 25-29 years (38.7)
• Free State 31.1

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Introduction

• Staging of CD4 count by the Centers for Disease
• Control and prevention
• Category 1 gt500 - healthy level
• Category 2 200-499 - immune system damage
• Category 3 lt200 weakened immune system,
  serious infections, other health problems

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Introduction

• Common blood cell abnormalities in HIV
  participants
• Anaemia (?HB)
• ?WCC (especially neutropenia)
• Thrombocytopenia (?PLT)

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Aim

• To determine
• the prevalence of HIV in rural South Free State
• the affect of HIV on CD4 count
• Blood cell abnormalities in HIV participants

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Methods

• HIV
• Screening test Enzygnost HIV Integral II Ag/Ab
  test
• Confirmation test Vironostica HIV Uni-Form II
  Ag/Ab test
• CD4 Count
• Beckman Coulter Epics XL Flowcytometer
• FBC
• Roche Sysmex XT 2000i

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Plt0.05
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5.7
74.3
37.2
20.0
Anaemia
Normochromic normocytic anaemia
Hypochromic microcytic anaemia
Macrocytic anaemia
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Discussion

• The prevalence of HIV was higher in males (18.2
  ) than in females (16.5)
• Highest prevalence in HIV group 31-40 years
• Highest prevalence in HIV- group 51-60 years
• Lowest CD4 counts in age group 41-50 years
• High prevalence of anaemia in HIV group
• Prominent white cell disorders in HIV group