Designing Health Research Lecture Week 3

1
Designing Health Research Lecture Week 3

• Ethics in Research
• Rob Heard

2
Summary of week 3

• Ethical violations in research
• International agreements about research
• Principles of research ethics
• The NHMRC

3
Syphilis

• Syphilis is a sexually transmitted disease
• Infection proceeds in 3 stages primary
  secondary and tertiary.
• It causes severe long-term damage
• Historically was treated with mercury, arsenic or
  malaria
• Is now treated with antibiotics

4
Bill Clintons apology (before Monica)
5
What they did at Tuskegee
6
International agreements governing research
local versions

• The Nuremberg Accords
• The Declarations of Helsinki
• The Belmont Report
• The National Health Medical Research Council
  guidelines.
• http//www.health.gov.au/nhmrc/index.htm

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Major ethical issues in research

• Informed consent
• Participation must not be coerced
• Participants must not be harmed
• Privacy must be protected
• Only worthwhile research is allowed
• Research must be approved by an Institutional
  Review Board

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Major approaches to ethics

• Deontology
• Utilitarianism
• The four principle approach
• beneficence
• non-maleficence
• autonomy
• justice