IUI A to Z

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IUIA to Z
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TYPICAL PREGNANCY RATE PER CYCLE WITH
VARIOUS TREATMENT OPTIONS
In Infertility
Method Pregnancy Rate ()
Intercourse (Timed) 4 (Follicle Monitoring) 1
IUI 6 ---do----
CC 6 ---do----
CCIUI 8 2
FSH / HMG 7.7
CC / FSH /IUI 9-12 3
FSH/ HMG/IUI 17 20 5
In vitro fertilization 20 to maximum 30
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Effect of Etiology on Success Rate with IUI
Infertility Etiology Pregnancy Rate (Maximum)
Unexplained 22.6
Mild male factor 18.8
Anovulation 12.4
Endometriosis 6.5
Tubal Factor 6.5
Combined factors 9.7
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• Endometriosis,Tubal factor, severe male factor
  and combined factor should proceed earlier to
  higher
• level ART

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Our IUI Experience (2009- 2011)

• N 369 23.57 (two cycles)
• (world over success rate 10 to 15 only)
• Idiopathic - 30 - (2 cycles)
• PCOD 30 - (r FSH) (2 cycles)
• Cervical Factor 20
• Endometriosis 15
• After treatment for TB 15
• Immunological cause TNF ? (treated ) 5

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• Male Infertility
• 5 - 20 millions 15
• Less then 5 million Nil
• AID 46 (2 cycles)

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Success rates according to AGE

• (Success rate in 1st 2 cycles)
• Less then 30 28
• Less then 35 22
• 35- 39 years - 8
• 40 Nil

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PREREQUISITES

• Age lt 40 yrs
• Spont. / Induced ovulation
• One patent FT
• gt10 million pre wash semen count
• gt5 million post wash semen count
• Easy access to uterine cavity

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INTRAUTERINE INSEMINATION (IUI) Steps

• 1. Patients selection workup
• 2. Ovarian stimulation
• 3. Semen wash
• 4. Insemination technique
• 5. Luteal support

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What is the difference between IUI
Artificial Insemination
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EJACULATORY FAILURE

• Severe hypospadias
• Retro grade ejaculation
• Paraplegics
• Impotence erectile dysfunction

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Super ovulationV/sControl Ovarian
Hyperstimulation

• Stimulation
• Monitoring
• Follicle growth release of multiple eggs

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How Many Eggs ?
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Office visits 4 - 6
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Complication of IUI Stimulation , Technique
others
- Infection -Rare - Multiple Pregnancy- OHSS
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Can we have sex in Rx cycle ?
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IUI is a simple procedureEasy Nurses
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IUI Preparation in Doctors office
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? 37 yrs married to 10 yrswhat should be done
?