THE BIOTECH INDUSTRY:

1
THE BIOTECH INDUSTRY
Firms that produce, analyse, or use biological
systems on a micro-, cellular-, or molecular
level or firms that develops tools and supplies
for these purposes.
2
The Swedish biotech industry

• Agrobiotechnology - plant improvement and
  biological plant protection
• Bioproduction - biomolecular or micro-organism
  production
• Biotech tools and supplies - services,
  processes, equipment and instruments for
  biotechnological use
• Environmental biotechnology - soil, water, and
  waste treatment
• Functional food and feed - mainly probiotics
• Pharmaceuticals and medicine - drug discovery
  and drug development, diagnostics and medical
  technology

3
Number of biotechnology companies in different
countries year 2000

Source The Swedish Trade council, Global
perspectives on bioscience 2002
4
Number of companies and employees
5
The regional distribution of the Swedish biotech
industry 1999
No. of employees
No. of companies
The sizes of the circles are proportional to
the number of employees/companies. Only micro-,
and small sized companies (lt200 employees) are
included. The distribution is based on the seat
of the county government.
6
Number of companies
7
Number of employees
8
Turnover
9
Number of companies pharmaceuticals medicine
10
Number of employees in pharmaceuticals medicine
11
Median equity/assets ratio
80
Finacial strength, median ()
Agrobiotechnology
70
Bioproduction
60
Biotech tools supplies
50
Environmental biotechnology
40
Functional food feed
30
Pharmaceuticals medicine
20
1997
1998
1999
2000
Year
12
Net profits/losses in surviving companies in
the different biotech sectors, 1998 2001
13
Share of surviving companies with net profit
1998-2001 in total and in each sector
14
Size of sector in Sweden

• PHARMACEUTICALS AND MEDICAL TECHNOLOGY
• Approximately 30 000 employees and a turnover of
  60 billion SEK
• BIOTECHNOLOGY
• The fourth largest biotechnology industry in
  Europe after
• Great Britain, Germany, and France and the
  ninth in the world
• 183 SMEs (lt 500 emp. each), increase by 35
  1997-2001
• About 4000 employees, increase by 48 1997-2001
• Turnover 4.4 billion SEK (2000), increase by 30
  1997-2000
• Increased financial strength and net losses
  1997-2001

European Commission Ernst Young The
Swedish Trade Council Fixed prices
15
Reasons for the development

• UNTIL 1999
• The science base
• The presence of Astra and Pharmacia
• An internationally growing market
• Success stories inspires
• Changed attitudes
• Good availability of seed and venture capital
• CHANGE DURING 2000-20022003
• Development at the stock exchange
• Cautious venture capital companies
• Lack of seed capital

16
The Swedish science base in international
comparison

• THE SWEDISH SCIENTIFIC PERFORMANCE IN GENERAL
• The trend is increased quantity but at the same
  time there are
• signs of decreasing quality.
• PERFORMANCE IN A SELECTION OF LIFE SCIENCE FIELDS
• First, second or third ranking of publication
  volumes in relation to
• population in the selected seven subject
  fields.
• Five out of seven fields showed increasing
  shares of the worlds
• total publication volume.
• Four out of seven fields showed increased
  citation levels but
• still Swedish citation levels are loosing
  their top position

17
Swedish ranking in relation to population
1986-2001
1986-1989 1990-1993 1994-1997 1998-2001 Total 87-01
Biochemistry Biophysics 2 2 2 2 2
Biotechnol Appl Microbiol 3 4 3 1 2
Cell Developmental Biol 3 3 2 2 2
Immunology 1 2 2 2 2
Microbiology 2 2 4 3 3
Molecular Biology Genetics 2 2 3 2 2
Neurosciences Behavior 1 1 1 1 1
18
Relative citation levels in biochemistry and
biophysics
19
Relative citation levels in neurosciences and
behavior
20
Volume shares for the nine most productive
Swedish public research organisations of the
total Swedish publication volumein
biotechnology-related science, 1987-2001
21
Co-authorship pattern between organisations with
the largest publication volumes in biotechnology
related science 1997-2001
22
The Swedish percentage of the worlds total
publication volume within a selection of life
science fields during five periods (1987-2001)

23
Relative citation levels for Swedish articles
within a selection of life science fields during
1987-1997 (Index world1)
24
Inventor origin for biotechnology patents in the
US patent system 1987-2001
Sweden lt 1
25
Swedish inventor shares of the worlds total
patenting volume during five periods in different
areas compared to the Swedish average share in
all fields 1987-2001
26
Number of patents for Astra and Pharmacia