???????? (gestational trophoblastic disease) ?????????????????? ????:??????????? ????

1
???? ???????? ?????

2
????????(gestational
trophoblastic disease)?????????????????????????
???????? ????
????
3
??? ???
4
????
??? hydatidiform mole, HM
?????????????,????????,????,???????,????
???? ????????? ?????/???
5
???
6
????
????????????
???????????
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7
??????
??????

• 1???
• ???????
• ??????????
• ??
• ?????

8
??????

• 2???
• ?????????
• ??????
• ????????????????? ?

9
??????

• 3?????
• ???????????
• HCG???????
• ??????????????

10
??????
????????
11
??????
????,????????????????????,????????
12
??????
??????????
??????????????????????????
?????????????
13
??????
1.???? ????????,????????,????
2.?????? ????,????,HCG
14
??????
3.????
???? ??????? ?? ?????? ??
???????????
15
??????
4.??????? ?????????? ????1?????2???? ????
??????,????????HCG (???????),3????????,?3???
????,??????,?2??????2??
16
??? ??????
17
????
??????(invasive mole)
???????????????????, ????????????6????
18
????

• ????????,???????
• ????/???????

19
??????
?????? 1??????
????? ? ????????
? ??????????
? ????????
20
??????
21
??????
2????????HCG?? ????????
22
??????
?????,???????
23
??????
????????????????????????
???????????
???????????????? ??
24
??????
1.???? ????????,????????,????
2.?????? ???,????,????,HCG
25
??????
3. ??????
???? ??????????????
26
??????

• 4. ????????
• (1)????
• ????????????,?????????????
• ????
• ??????,???????????

27
??????

• (2)???
• ????
• ????
• ????????????????????,???????

28
??????

• (3)???
• ??????
• ????
• ?????
• ????
• ?????????

29
??????

5.?????? ?????????? ????1?????2???? ????
??????,????????HCG (???????),3????????,?3????
???,??????,?2??????2??
30
??? ????
31
????
????(choriocarcinoma)

• ??????????
• ???????,???,???????
• ???????,???????????

32
????

• ???????????,?????????
• ??????

33
????
34
??????

• ??????
• 1??????
• ????
• ????
• ????
• ??
• ????????????

35
??????

• ??????
• 2?????
• ???????????????????,???
• ??HCG???????
• ????????

36
??????
????,????
37
??????
?????????????????
?????????????????
???????????????
38
??????
1.?????????
2.?????????????
3.????
4.??????
5.????
39
??????
???
????
???????????
40
??? ???????
41
????

• ???????????????????????????????????????,?????
• ???????????????????

42
??????
1.??DNA?? 2.??RNA?? 3.???????mRNA?? 4.??????? 5.??
?????
43
?????--?????????
1.??????????? 2.???????? 3.????? 4.?? 5.???????,?
????
44
??????
???? ????????????????????
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????????????????
45
??????
1.???? ?????????????????????????
2.?????????????
3.??????????,?????
4.????
46
??????

• 5???????
• (1)??????
• ??????
• ?????????
• (2)????????????
• (3)????????????????