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RESEARCH IN MOLECULAR GENETICS

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RESEARCH IN MOLECULAR GENETICS BASIC INTRODUCTION TO THE COURSE * * * * * * * * * * * * Concept of Course Best way to learn science is by doing science What ... – PowerPoint PPT presentation

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Title: RESEARCH IN MOLECULAR GENETICS


1
RESEARCH IN MOLECULAR GENETICS
  • BASIC INTRODUCTION TO THE COURSE

2
Concept of Course
  • Best way to learn science is by doing science

3
What is the best way to learn piano?
  • Reading how to play piano in a text book.
  • Listening to a lecture on playing piano.
  • Practicing playing piano.

4
What is the best way to learn how to play
baseball?
  • Studying a book on baseball.
  • Listening to a lecture on how to play baseball.
  • Playing baseball

5
Unfortunately, science is a complex subject
  • It does require learning a lot of facts
  • Remember science last year?
  • What you get in school (from 1st grade to 4th
    year of college) is a recitation of what science
    has found out.
  • In essence, you learn the history of science.

6
Facts important, but not the whole story
  • Memorizing facts is only a small part of science

7
By actually doing science
  • You will experience what real science is about.
  • Truly, know if you like science or not.

8
Hopefully, you will come to appreciate the
  • Beauty
  • Excitement
  • Fun
  • Creativity
  • Of the scientific enterprise

9
Hopefully, by actually doing science
  • You will learn the discoveries of science (the
    facts) as a by product of your activities
  • You will see how these facts are applied to real
    life situations
  • Thus facts will have a greater depth of meaning
    and relevance

10
Hopefully, you will also learn that science is a
people activity
  • It depends on people trying to persuade one
    another that theyre right and the other guy is
    wrong.

11
Hopefully, you will see that science requires
  • Practice
  • Creativity
  • Intellect
  • Persuasive ability
  • Writing skills
  • Social skills
  • Much more

12
The goals of this course is
  • To learn the basic principles of molecular
    genetics
  • Learn how science operates

13
Why is this important?
  • In the 21st century our ability to manipulate
    biology will require the public to make momentous
    decisions.
  • These decisions should be made from an informed
    point of view.

14
Such decisions may involve
  • Stem cell research and its applications
  • Cloning and its applications
  • Creating designer babies
  • DNA identification cards
  • Transgenic organisms
  • Genetic testing for life and health insurance and
    job applications
  • Gene patenting

15
Why molecular Genetics?
  • Foundation of all the biological sciences.
  • An understanding of genes is central to an
    understanding of all biology.
  • All of the various facts that seem to be
    unrelated in biology can be woven into a coherent
    whole with molecular genetics as the unifying
    concept.

16
Connecting diverse branches of biology with
molecular genetics
  • Developmental biology-Ultimately is the study of
    what genes are turned on and what genes are
    turned off (gene regulation).
  • Physiology and morphology-Ultimately is the study
    of what proteins are expressed by genes.
  • Ecology-Ultimately is the study of genetic
    changes that allow for adaptation to the
    environment
  • Evolution-Ultimately is the study of change in
    gene frequency in a population over time.
  • Taxonomy-Ultimately is the study of genetic
    differences and similarities between species.

17
Definition of molecular genetics
  • The study of the biological molecules that pass
    information from generation to generation.
  • It involves the study of the structure and
    activity of the genetic material at the molecule
    level.
  • The major biological molecules involved are DNA
    and proteins.

18
Activities of genetic material
  • It makes copies of itself-DNA replication
    (involves DNA and proteins)
  • Genes are turned on and off as needed-transcriptio
    n and translation (involves nucleic acids and
    proteins)
  • Changes in DNA-mutations
  • Products of genes-phenotype (involves nucleic
    acids, protein structure and function)

19
Structure of genetic material
  • Chromosome-is the structure that contains the
    genetic material that is passed from generation
    to generation.
  • Consists of one long DNA molecule and proteins.

20
Relationship between chromosome,DNA, and gene
  • Chromosome-structure within cell that contains
    the genetic material as threadlike DNA surrounded
    by proteins
  • DNA-A nucleic acid molecule that contains the
    genetic information.
  • Gene-Segment of DNA (on a specific site on a
    chromosome) that is responsible for the physical
    and inheritable characteristics (trait) of an
    organism usually by specifying a protein.

21
Closer look at gene on DNA
22
More detailed look at gene and DNA
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