Pre-Krebs and Krebs Cycle

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Pre-Krebs and Krebs Cycle
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• Take place in the mitochondria
• 2 pyruvate molecules enter the mitochondria from
  the cytoplasm
• 3 Functions
• Produces NADH and FADH2
• Produces ATP
• Produces oxaloacetate

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• Pre-Krebs
• 1. Pyruvate enters the mitochondria from the
  cytoplasm
• 2. CO2 is removed from pyruvate and Acetyl CoA is
  formed
• NAD is converted to NADH

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• Krebs Cycle (Citric Acid)
• 3. Acetyl CoA attaches to oxaleacetate creating
  citrate
• 4. Citrate breaks down into intermediates,
  releasing CO2
• 4. NADH is produced
• 5. ATP is formed
• 6. FADH2 is produced

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• 7. Oxaloacetate is regenerated and continues in
  the Citric Acid Cycle.