Chapter 14 Gene Control in Development

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Chapter 14Gene Control in Development

• Thu Fenno

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Pheromone-Stimulated Gene Expression

• Upon completion of this lesson the students will
  be able to
• Identify Yeast (Review)
• Identify Cell Types in Yeast
• Identify Regulating Pheromone

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Yeast(Review)

• Unicellular Eukaryote
• Divides by budding
• Exist as haploid or diploid cells
• Undergo aerobic or anaerobic respiration
• Saccharomyces cerevisiae

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Morphology of Yeast Cell Type
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Cell Types in S. cerevisiae
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Pheromone-Stimulated Gene Expression

• Haploid yeast cells produce pheromones and
  pheromone receptors

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• Eukaryotic Cell Cycle

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Conclusion

• S. cerevisiae expresses three different cell
  types the two haploid cell types (a and a
  cells), and the diploid a/a cells.
• Haploid cells produce pheromones and pheromone
  receptors.
• Binding of the pheromones to their receptors on
  cells of the opposite type leads to gene
  activation and arrest in the G1 phase of the cell
  cycle.
• Fusion of the haploid cells form diploid cells.
• In the presence of sufficient nutrients, these
  cells will grow as diploids. Starvation induces
  diploid cells to undergo meiosis and form four
  haploid spores.