Self-experimentation in medicine

1
Self-experimentation in medicine
2

• Notable examples of medical self-experimentation
• ABO blood group
• Cardiac catheterization
• Thrombocytopenia
• Helicobacter pylori
• Cholera
• Effects of forces on the body
• Psychoactive drugs
• Yellow fever
• Alcohol
• Heavy water
• Neural implant
• Skin transplant
• Snake bite
• Weight balance
• Asthma
• Bartonellosis

3
John Hunter
1728-1793

• one of the most distinguished scientists and
  surgeons of his day
• self-inoculation with gonorrhea and syphilis
• Jekyll Hyde

Charles Byrne (8 1)
4
William Harvey

• Discoveries
• Disproved Galen that blood not made from the
  liver
• Heart is a pump not a suction device
• Showed closed circuit circulation
• Showed existence of valves in veins

1578-1657
5
Max von Pettenkofer
1818-1901
drank choleric bacteria.

• miasma, noxious air associated with the air from
  rotting or fecal material
• Contagionists, disease caused by something that
  was catching, like smallpox or syphilis

6
Werner Forssmann 1930s
Cardiac catheterization

• Won the Nobel Prize for medicine
• Hospital administrators removed him from his
  position owing to his unorthodox methods.

7
Barry Marshall
Helicobacter pylori
Ulcer
8
Tim Friede
Snakebite anti-venom
Black mamba
http//timfriede.com/
9
Craig Venter
Celera Genomics
10
Disturbing Experiments
11
Disturbing Experiments

• Inter-species breeding (ape-man, Ilya Ivanovich
  Ivanov, Guinea, 1927)

12
Disturbing Experiments

• Two-headed dog (Vladimir Petrovich Demikhov,
  1950s, Russia)

http//www.youtube.com/watch?vuvZThr3POlQ