Title: Medical Surgical Nursing
1Medical Surgical Nursing
2Endocrine Pancreas
- Islets of Langerhans
- Beta cells
- Insulin
3Insulin
- Produced and secreted by
- Beta cells
4Insulin
- Primary function
- Stimulates the active transport of glucose
- from the blood into muscle, liver and adipose
tissue ? - __?__ blood glucose levels
- i
5Glucose Content of Food
- Consume food ? glucose ? blood stream
- Carbohydrates
- Starch
- Simple
- Complex
6Secretion of Insulin
- Is stimulated by
- What change in homeostasis causes the beta cells
to secrete insulin? - Hyperglycemia
- Glucose levels in the bloodstream regulate the
rate of insulin secretion
7The major action of insulin
- i blood glucose levels
- h the permeability of target cell membrane to
glucose - Main target cells
- Muscle
- Liver
- Adipose tissue
8Pathophysiology sumamry
- Increased blood glucose levels ?
- Gland
- Pancreas ?
- B cells ?
- Insulin ?
- Target cells (muscles) ?
- (insulin pulls glucose from the blood into the
muscles) ? - Decrease blood glucose levels
9Insulin info
- In the absence of insulin, glucose is not able to
get into the cells and it is excreted in the
urine - Glycouria
- Brain cells are not dependent on insulin for
glucose intake
10Function of Insulin
- Need insulin for glucose to cross cell membrane
- No insulin ? no glucose into the cell
- Glucose stays in the blood ?
- Hyperglycemia
11Diagnostic tests
- Blood glucose / Fasting blood glucose
- Glycosylated Hemoglobin Assay
12Blood Glucose Fasting blood Glucose
- Measures blood glucose levels after fasting
- Results
- Normal 70-115 mg/dL
- Diabetic level gt 126 mg/dL
- Critical gt 400 mg/dL
- Critical lt 50 mg/dL
13Fasting Blood GlucoseNursing Responsibility
- Fast 6-8 hours
- Water OK
- No insulin or anti-diabetic meds
- Exercise will effect results
14Glycosylated Hemoglobin Assays (Hgb A1C)
- of glycosylated hemoglobin
- RBC lifecycle
- _at_ 120 days (4 months)
- Glucose slowly binds with Hgb ? glycosylated
- h serum glucose level ? h glycosylated Hgb
levels
15Hgb A1C
- Provides an average blood glucose levels
- Past 2-3 months
- Can be taken any time
16- Normal levels (non-diabetic)
- 4-6
- Diabetic level (goal)
- lt8
17Small group questions
- What are the Islets of Langerhans?
- What cells of the pancreas secrete insulin?
- What stimulates insulin to be secreted?
18What is diabetes mellitus?
- Group of disordered characterized by chronic
hyperglycemia - Due to faulty insulin production
- (Not Diabetes Insipidus)
19Type 1 Diabetes Mellitus
- Destruction of the Beta cells
- Result in
- NO insulin production
- Insulin dependent
20SS of Type 1 DM
- Hyperglycemia
- ? blood glucose levels
- No insulin ?
- Glucose stays in the blood stream
21SS of Type 1 DM
- Glycosuria
- Glucose in the urine
22SS of type 1 DM
23SS of Type 1 DM
- Polydipsia
- Excessive thirst
24SS of Type 1 DM
- Polyphagia
- Excessive hunger
25SS of Type 1 DM
- Dehydration
- Assessment?
- Skin turger
- Mucus membranes
- Thirst
- BUN level
26Small Group Questions
- Why would a person with high glucose levels have
polyphagia? - Explain why polyuria is a common symptom of
diabetes Mellitus Type 1. - What is hyperglycemia?
- Why does hyperglycemia happen in Type 1 diabetes
mellitus?
27Small Group Questions
- 5. What is a normal level for a FBS?
- 6. Define the following terms Glucose,
Glycosuria. - 7. What does an Hgb A1c measure? What are normal
values for a diabetic and non-diabetic?
28Type 2 DM
- Pathophysiology
- The pancreas cannot produce enough insulin for
bodys needs - Impaired insulin secretion
29Type 2 DM
- Weakened Beta cells Due to over use
30Insulin and Type 2 DM
- Not all clients require insulin
- 1/3 will at some time
- Stress
- Illness
31Risk Factors for Type 2 DM
- Family history
- Obesity
- Gestational diabetes or large baby
32Type 1 vs. Type 2
- Age of onset
- Usually lt 30
- Age of onset
- Usually gt 40
33Type 1 vs. Type 2
- Body wt at onset
- Normal to thin
- Insulin production
- None
- Insulin injections
- Always
- Body wt at onset
- 80 overweight
- Insulin production
- Not enough
- Insulin injections
- Sometimes
34Type 1 vs. Type 2
- Management
- Insulin
- Diet
- Exercise
- Management
- Diet (wt. Loss)
- Exercise
- Possibly oral hypoglycemic meds
- Possibly insulin
35Other specific types of Diabetes Mellitus
- Gestational
- Pancreatitis
- Drug or chemical induces diabetes (steroids)
36SS of Diabetes Mellitus
- Definition
- A group of disorders characterized by chronic
Hyperglycemia - 3 Ps
- Polydipsia
- Polyuria
- Polyphagia
37SS of Hyperglycemia
- Neurological
- C/O headache
- Dull senses
- Stupor
- Drowsy
- Blurred Vision
38SS of Hyperglycemia
- Cardiovascular
- Tachycardia
- Decreased BP
- (Dehydration)
- Respiratory
- Kussmaul's respirations
- Sweet and fruity breath
- Acetone breath
39SS of Hyperglycemia
- Gastro-intestinal
- Polyphagia
- N/V
- Polydipsia
40SS of Hyperglycemia
- Genital-urinary
- Polyuria
- Glycosuria
- Skeletal-muscular
- Weak
41SS of Hyperglycemia
- Integumentary
- Dry skin
- Flushed face
42Small Group Questions
- Mr. McMillan is a 50 year old client brough into
the ER with extreme fatigue and dehydration.
After the MD sees him the nurses asks Mr.
McMillan some additional questions. Based on the
clients answers the nurse requests that the MD
add a glucose level to the lab work. The results
are 800mg/dL.
43Small group questions
- What question did the nurse most likely ask?
- Why was Mr. McMillan fatigued?
- Why was he dehydrated?
44Medical Management of DM
- No cure
- Goal is Control! And prevent complications
- Individualized treatment plans
- Diet
- Exercise
- Meds
45Dietary management of DMFoundation of Diabetic
control
- Goals
- Maintain near-normal blood glucose levels
- Achieve optimal serum lipid levels
- Provide adequate calories for reasonable weight
- Prevent treat acute complications of
insulin-treated diabetes - Improve overall health through optimal nutrition
46The exchange system
- Six categories
- Starch
- Meat
- Milk
- Vegetable
- Fruit
- Fat
47General guidelines of Dietary Management
- Protein
- 20
- Fat
- 20
- Carbohydrates
- 60
- ADA American Diabetic Association
48Diabetic Meal Plan
- Small frequent meals
- CONSISTENCY!
- Amount of calories
- Amount of carbohydrates
- Time
- Snacks
49Diabetic Meal Plan
- If the client is obese, the key to treatment is
- Weight loss!
50Meal Plan considerations
- Food preferences
- Lifestyle
- Schedule
- Ethnic / Cultural background
51Alcohol and Diabetes
- Increase risk of
- Hypoglycemia
- Moderation
52Exercise and Diabetes
53More Benefits of exercise
- Increases circulation
- Improve serum lipid levels
- Improves cardiovascular status
- Assist with wt control
- Decreases stress
54Rules for the exercising diabetic
- Talk to MD first
- Regular vs. sporadic
- Correlate exercise and glucose levels
- Dont exercise when hypoglycemic
- Dont exercise when hyperglycemic gt250
55Rules for the exercising diabetic
- Do not exercise when insulin is peaking
- Carry a quick source of sugar
- Best time 60-90 minutes after a meal
56Rules for the exercising diabetic
- Proper footwear
- May need a pre-exercise snack
- Consistency!
57Monitoring Glucose
- Glucometers
- FSBS
- 2-4 times a day
58Small Group Questions
- Give signs symptoms of hyperglycemia by body
system (Why do they manifest these symptoms?) - A diabetic meal plans main goal is to maintain
near normal glucose levels. How is this done? - The exchange diabetic meal plan is divided into
six categories, what are they?
59Small Group Questions
- 4. What affect does alcohol have on a diabetic?
- 5. What affect does exercise have on a diabetic?
- 6. What council would you give a diabetic
regarding exercise?
60Onset Peak - Duration
- Onset
- The time period from injection to when it begins
to take effect - Peak
- When insulin is working its hardest and therefore
blood glucose levels are at their lowest
61Onset Peak - Duration
- Duration
- Length of time the insulin works or lasts
62Types of Insulin Very short acting/ rapid
acting
- Lispro (Humalog)
- Aspart (Novolog)
- Insulin pumps
- Rapid reduction of glucose level
Appearance Onset Peak Duration
Clear ¼ hour 1 hour 3 hours
63Types of Insulin Short-acting / regular
- Humalog R Novolin R Iletin II Regular
Appearance Onset Peak Duration
64Types of Insulin Short-acting / regular
- Humalog R Novolin R Iletin II Regular
Appearance Onset Peak Duration
Clear
65Types of Insulin Short-acting / regular
- Humalog R Novolin R Iletin II Regular
Appearance Onset Peak Duration
Clear ½ - 1 hr (1 hour)
66Types of Insulin Short-acting / regular
- Humalog R Novolin R Iletin II Regular
Appearance Onset Peak Duration
Clear ½ - 1 hr (1 hour) 2-3 hrs (3 hour)
67Types of Insulin Short-acting / regular
- Humalog R Novolin R Iletin II Regular
- Administered 20-30 minutes before meals
- IV
- Usually given 4 x a day
Appearance Onset Peak Duration
Clear ½ - 1 hr (1 hour) 2-3 hrs (3 hour) 4-6 hrs (5 hours)
68Types of Insulin Intermediate-acting
- NPH Humulin N Lente Novolin L Novolin N
Appearance Onset Peak Duration
69Types of Insulin Intermediate-acting
- NPH Humulin N Lente Novolin L Novolin N
Appearance Onset Peak Duration
Cloudy
70Types of Insulin Intermediate-acting
- NPH Humulin N Lente Novolin L Novolin N
Appearance Onset Peak Duration
Cloudy 2-4 hrs (2 hrs)
71Types of Insulin Intermediate-acting
- NPH Humulin N Lente Novolin L Novolin N
Appearance Onset Peak Duration
Cloudy 2-4 hrs (2 hrs) 6-12 hrs (12 hrs)
72Types of Insulin Intermediate-acting
- NPH Humulin N Lente Novolin L Novolin N
- Administer after meals
- Usually given 2x a day
- Eat at onset!
Appearance Onset Peak Duration
Cloudy 2-4 hrs (2 hrs) 6-12 hrs (12 hrs) 16-20 hrs (24 hrs)
73Learning Tip Even and Odd
- Short-acting think odd
- (1-3-5)
- Intermediate-acting think even
- (2-12-24)
-
74Regular vs. Intermediate (NPH)
75When should insulin be administered
- Short-acting / regular
- 30 min before meals (ac)
- Do not allow more than 30 min to pass by without
eating - ? hypoglycemia
- Intermediate acting
- After meals (pc)
- If mixed (regular intermediate)
- 30 min before meals
76What route is insulin administered
77Syringe Types
- Insulin syringe
- 27-29 gauge
78Route (Self Administration)
- Subcutaneous tissue
- If you can pinch an inch
- 90 degree angle
- If you cant pinch an inch
- 45 degree angle
79Areas of injection
80Factors affecting absorption rates
81What would you do?
- Which of the following is frequently best to
teach / do first when doing initial diabetic
training? - How where to purchase insulin
- Preparation storage of insulin
- Mixing insulin with return demonstration
- Self-injection of insulin
- Learning O-P-D of insulin types
82Insulin Pumps
- Portable infusion pump
- Subcutaneous needle
- Continuous/basal rate
- Additional bolus if needed
- Change site q24-48 hours
83Insulin Pumps
- S/E - risks
- Hypoglycemia
- Infection
- Hyperglycemia
84Small Group Question
- Mrs. Evans is 60 year old women with type 2 DM.
She is on Intermediate Acting Insulin Novolin L
(Lente) every morning. She normally eats her
meals at 800 AM, 1200 PM, and 600 PM. - What time should she take her morning insulin?
- When will this dose onset?
- When will this does peak?
- What does this insulin look like?
85Mrs. Sweet Peas takes 13 units of Short-Acting
Insulin Humalog R q ac. Her meals are B-800
AM, L-1200 PM, D-700PM
- What time should Mrs. Peas take her mid-day
(lunch)dose of insulin? - When this dose onset?
- When will this dose peak?
- What does this insulin look like?
86Mrs. Gumdrop takes 6 units of Intermediate Acting
Insulin NPH at HS (10PM). She eats her meals
at B-7AM, L-11AM, D-5PM.
- When will this dose onset?
- 9 AM
- 730 AM
- 7 PM
- 1030 PM
- 12 AM
87Mrs. Gumdrop takes 6 units of Intermediate Acting
Insulin NPH at HS (10PM). She eats her meals
at B-7AM, L-11AM, D-5PM.
- When will this dose peak?
- 1 AM
- 10 PM
- 10 AM
- 9 PM
- None of the above
88Mrs. Gumdrop takes 6 units of Intermediate Acting
Insulin NPH at HS (10PM). She eats her meals
at B-7AM, L-11AM, D-5PM.
- What does this insulin look like?
- Clear
- Cloudy
89Mr. Chocolate Chip Cookie takes 10 units of
Regular Insulin Novolin R q AM. His meals are
at B-7AM, L-11AM, D-5PM.
- When should he take his morning does of insulin?
- 6 AM
- 630 AM
- 7 AM
- 730 AM
- None of the above
90Mr. Chocolate Chip Cookie takes 10 units of
Regular Insulin Novolin R q AM. His meals are
at B-7AM, L-11AM, D-5PM.
- When will this does peak?
- 730 AM
- 830 AM
- 930 AM
- 1030 AM
- None of the above
91Mr. Chocolate Chip Cookie takes 10 units of
Regular Insulin Novolin R q AM. His meals are
at B-7AM, L-11AM, D-5PM.
- What does this insulin look like?
- Clear
- Cloudy
92Ms. Eng Ewe takes 10 units of Short-Acting
Insulin Iletin II Lente and 5 units of
Intermediate Acting Insulin NPH q AM. Her
meals are B-8AM, L-12PM, D-7PM
- When should she take her insulin injection?
- 700 AM
- 800 AM
- 900 AM
- 1000 AM
- None of the above
93Ms. Eng Ewe takes 10 units of Short-Acting
Insulin Iletin II Lente and 5 units of
Intermediate Acting Insulin NPH q AM. Her
meals are B-8AM, L-12PM, D-7PM
- When will her insulin onset
- When will her insulin peak
94Mixing Insulin How to
- 1 Assemble equipment
- Insulin
- Syringe
- Alcohol swab
- MD order
95Mixing insulin How to
- 2 Check MD order for dose and types
96Mixing insulin How it
- 3 Roll the bottle of intermediate acting
insulin (DO NOT SHAKE)
97Mixing insulin How it
- 4 Wipe the top of both vials with alcohol swab
98Mixing insulin How it
- 5 Draw up and inject an amount of air equal to
the dose of intermediate acting insulin into the
cloudy vial. Then remove syringe from the vial
99Mixing insulin How it
- 6 Draw up and inject an amount of air equal to
the amount of short-acting insulin into the clear
vial. Leave syringe in the vial
100Mixing insulin How it
- 7 Draw up the correct amount of clear/regular
insulin.
101Mixing insulin How it
- 8 Double check with another nurse if this is the
institutions policy.
102Mixing insulin How it
- 9 Remove the syringe and insert into the cloudy
vial. Carefully draw up the correct amount of
insulin.
103Mixing insulin How it
- 10 Double check with another nurse before
removing the syringe from the vial
104What do you do if you draw up too much
intermediate acting insulin with mixing?
- Push it back into the vial and re-draw up the
correct amount. - Waste the med and start over with the same
syringe. - Waste the med and start over with a clean
syringe. - Who cares, a little extra never hurt anyone!
Just give it to the patient.
105What do you do if you draw up too much
Regular/clear insulin when mixing?
- Push it back into the vial and re-draw up the
correct amount. - Waste the med and start over with the same
syringe. - Waste the med and start over with a clean
syringe. - Who cares, a little extra never hurt anyone!
Just give it to the patient.
106How would you do it?
- Give 8u Humulin R and 12u NPH sub-q, qAM.
107Sliding Scale
- Used during
- Surgery
- Illness
- Stress
- Determines insulin dose based on FSBG
- FSBS check usually every 4-6 hrs
- Usually regular insulin is used
108Sample Sliding Scale
- Check FSBS before meals and at HS (2200)
- 4u Humulin R insulin for glucose 151-200 mg/dL
- 6u Humulin R insulin for glucose 201-250 mg/dL
- 8u Humulin R insulin for glucose 251-300 mg/dL
- 10u Humulin R insulin for glucose 301-350 mg/dL
- Call MD for glucose gt350 mg/dL
109Questions for sliding scale
- If FSBS 189 how much insulin would you give?
- None
- 4 units
- 6 units
- 8 units
- 10 units
- Check FSBS before meals and at HS (2200)
- 4u Humulin R insulin for glucose 151-200 mg/dL
- 6u Humulin R insulin for glucose 201-250 mg/dL
- 8u Humulin R insulin for glucose 251-300 mg/dL
- 10u Humulin R insulin for glucose 301-350 mg/dL
- Call MD for glucose gt350 mg/dL
110Questions for sliding scale
- If FSBS 309 how much insulin would you give?
- None
- 4 units
- 6 units
- 8 units
- 10 units
- Check FSBS before meals and at HS (2200)
- 4u Humulin R insulin for glucose 151-200 mg/dL
- 6u Humulin R insulin for glucose 201-250 mg/dL
- 8u Humulin R insulin for glucose 251-300 mg/dL
- 10u Humulin R insulin for glucose 301-350 mg/dL
- Call MD for glucose gt350 mg/dL
111Questions for sliding scale
- If FSBS 120 how much insulin would you give?
- None
- 4 units
- 6 units
- 8 units
- 10 units
- Check FSBS before meals and at HS (2200)
- 4u Humulin R insulin for glucose 151-200 mg/dL
- 6u Humulin R insulin for glucose 201-250 mg/dL
- 8u Humulin R insulin for glucose 251-300 mg/dL
- 10u Humulin R insulin for glucose 301-350 mg/dL
- Call MD for glucose gt350 mg/dL
112Questions for sliding scale
- If FSBS 60 how much insulin would you give?
- None
- 4 units
- 6 units
- 8 units
- 10 units
- Check FSBS before meals and at HS (2200)
- 4u Humulin R insulin for glucose 151-200 mg/dL
- 6u Humulin R insulin for glucose 201-250 mg/dL
- 8u Humulin R insulin for glucose 251-300 mg/dL
- 10u Humulin R insulin for glucose 301-350 mg/dL
- Call MD for glucose gt350 mg/dL
113Pre-mixed insulin
- NPH Regular
- Novolin 70/30
- 70 NPH
- 30 regular
114Insulin Storage
- Vial NOT being used ?refrigerate
- Vial in use ? room temperature
- Storage life un-refrigerated 1 month
115Insulin Therapy Complications
- Hypoglycemia
- Causes
- Too much insulin
- Too little food
- Extreme exercise
116SS of Hypoglycemia
- Neuro
- Dizzy / faint
- Nervous / Irritability
- Blurred vision
- Numb tongue or lips
117SS of Hypoglycemia
- Cardiovascular
- Full bounding pulse
- Respiratory
- Shallow breathing
- Gastro-intestinal
- Polyphagia
118SS of Hypoglycemia
- Genital-urinary
- No polydipsia
- No polyuria
- Skeletal/muscular
- Weak
- Trembling / tremor
- Integumentary
- Perspiring/ Moist
- Pale
119Small group Questions
- When is a sliding scale commonly used?
- A tuberculin syringe is also calibrated in units.
Is it OK to use a TB syringe to draw up insulin? - What route is insulin administered?
- Compare the signs and symptoms of hyper and
hypoglycemia
120- How come they are not all opposite signs and
symptoms? - Why are some so similar?
- Which symptoms can you look for to tell the
difference between hyper and hypoglycemia? () - What is the biggest risk factor in using an
insulin pump?
121Oral Hypoglycemic Agents
- SulfonylureaCholpropamide (Diabanese)
- Glipizide (Glucotrol)
- Glimepride (Amaryl)
- Glyburide (Diabeta, Micronase)
122Oral Hypoglycemic Agents
- Biguanides
- Metformin (Glucophage)
- Glucovance
- SulfonyureaBiguanide
123Oral Hypoglycemic Agents
- Oral hypoglycemic meds are not Insulin
- Oral hypoglycemic meds require some production of
insulin - Oral hypoglycemic agents are used in the
treatment of type ___DM - Type 2
- Oral hypoglycemic meds are meant to supplement
diet and exercise, not replace them
124Oral Hypoglycemic Agents
- Oral hypoglycemic meds cannot be used during
pregnancy - Oral hypoglycemic meds may need to be held
temporarily and insulin prescribed if BS levels
rise due to stress or illness etc. - Action varies so effect may be enhanced by use of
multiple meds
125Sulfonylureas
- Sulfonylureas work primarily by h the secretion
of insulin by directly stimulating the pancreas
126Sulfonylurea
- Side-effects of Sulfonylurea
- Hypoglycemia
- GI upset
127Biguanides
- Biguanides work primarily by aiding insulins
action on peripheral receptor sites (target
cells) - Biguanides are NOT associated with episodes of
hypoglycemia - Biguanides sulfonylurea may h the glucose
lowering effect
128Biguanides
- Major side effects of Metformin are
- Anorexia/ wt. Loss
- Metformin is contraindicated in patients with
Renal impairment
129Can diabetes pills help me?
- Only Type 2 DM
- Results vary
- Effectiveness wears off
- Insulin may still need to be taken occasionally
- Pregnant
130Small Group Questions
131Small Group Questions
- A type 1 DM asks you Why do I have to have
insulin injections, why cant I just take the
Insulin pills? How would you answer him? - Mrs. Murdock is a Type 2 DM. She was taking
Glucatrol 20 mg BID. The MD changed her meds
today to Micronase 5 mg PO BID and Glucophage 500
mg PO BID. Mrs. Murdock asks you why she is
taking two medications now, instead of just
increasing the dose of Glucatrol?
132Hypoglycemia
- Definition When blood glucose levels fall below
70mg/dL - lt 50mg/dL severe
133Hypoglycemia Etiology
- Any time
- Usually Before meals or a night
- Too much insulin or oral hypoglycemic meds
- Too little food
- Excessive exercise
134Hypoglycemia Dx Assessment
- Signs Symptoms
- Can occur suddenly!
- If pt is a long time diabetic ?
- No early SS
135Hypoglycemia Dx Assessment
- 1 Dx tool
- Lab Values
- FSBS
136Hypoglycemia can result
- When a patients baseline blood glucose level is
100mg/dL ? - Drops to 60 mg/dL
- When a patients baseline blood glucose level is
200mg/dL ? - Drops to 120 mg/dL
137Hypoglycemia Medical Management
- Assess for SS
- P blood sugar level
- Admin. fast sugar
138Hypoglycemic Protocol Sample
- For BG lt60 mg/dL
- If patient can take PO, give 15g of fast acting
carbohydrate. - Check FSBG q 15 minutes and repeat above if
BGlt80.
139Glucose Fast!
- 15 g fast acting carbohydrate
- 4-6 oz. Juice/soda
140Rules to remember
- Do not add sugar to OJ
- Recheck FSBS q 15 min until WNL
- Avoid high fat ? slows absorption of glucose
- Instruct carry fast sugar
- NPO if unconscious or confused
- If meal is gt1 hr away, follow with a protein and
complex carbohydrate
141Hypoglycemia treatmentUnconscious
142HypoglycemiaGerontological Consideration
- Cognitive deficits ?
- not recognize SS
- Decreased renal function ?
- oral hypoglycemic meds stay in body longer
- More likely to _________a meal
- Skip
- Vision problems ?
- inaccurate insulin draws
143HypoglycemiaNursing measures
- Follow protocol
- Teach
- Carry simple sugar at all times
- SS or hypoglycemia
- How to prevent Hypoglycemia
- Check FSBS if you suspect ? NOW!
144Treating Hyperglycemia
- Assess for
- SS
- Check
- FSBS
- Administer
- insulin per MD order
145Medical Management/treatment
- Monitor Fluid and electrolytes
- Especially K
- Push fluids