Title: Alzheimer
1Alzheimers Disease and Dementia Care for
Health Plan Case Managers
- Karen Bugg RN LMSW
- Institute for Health Care Studies
- Michigan State University
- August 16th 17th 2010
2What does dementia mean?
3Dementia and the Brain
- Injury to brain cells causes dementia.
- Dementia causes a decline in a persons ability
to think, understand, and remember and affects a
persons function. - Dementia gets worse over time.
4Dementia
- Because of memory loss
- no longer self-sufficient
- requires ongoing help or supervision
- functional dependency
5Activities of Daily Living
- Bathing
- Dressing
- Feeding Self
- Toileting
- Transferring
- Telephone
- Driving
- Shopping
- Meal Preparation
- Managing Finances
- Managing Medications
6Causes of Dementia
- Alzheimers disease is the most common cause of
dementia. - Other common causes are
- Vascular dementia
- Dementia with Lewy bodies
7Alzheimers definition
- A progressive degenerative neurological disease.
- Most common form of dementia in the elderly.
- Nearly 75 of all dementia cases.
8Alzheimers in the United States
- 5.3 million people
- One person is newly diagnosed every 70 seconds
- 7th leading cause of death
- Rates are expected to double every 20 years
9Alzheimers Disease - Statistics
- 6-8 of all persons age 65 and older
- 30-50 of all persons age 85 and older
- By 2029, all baby boomers will be at least 65
years old - 5.3 million cases currently, will increase to 18
million by 2040
10Race Ethnicity
- Older African Americans and Hispanics are much
more likely than older whites to have Alzheimers
disease and other dementias.
11Michigan
- In 2008, sixty-eight percent of nursing home
residents were cognitively impaired.
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13Current Dilemmas in Dementia Care
- Alzheimers disease is under diagnosed,
particularly among patients who do not speak
English as their primary language. - Pre-Alzheimers impairments are often attributed
to normal aging. - Denial and fear often delay evaluation.
- Typical lag time between symptom onset and
diagnosis is two years. - Most patients are not diagnosed by their primary
care physicians.
14Impact on health care
- Today, there are about 4,700 providers, up from
about 3,300 five years ago. - Alzheimer's disease now accounts for 10.1 percent
of hospice admissions nationwide, up from 5.5
percent in 2000. - ALHs beds have tripled over the decade from
600,000 to 2,000,000..
15The Future of Alzheimers Disease
- Treatment with current FDA approved drugs
- Disease modifying drugs to induce remission
- Medications to reverse memory loss
- Cure
16Investigational Treatments
- Passive immunotherapy
- Active immunization
- Secretase inhibitors
- Gene therapies
- Neurotrophics
17Brain Anatomy Function
18Healthy Brain Cells
- Billions of neurons
- Axons message transmitters
- Dendrites message receivers
- Groups of neurons have special functions
19Healthy Brain Processes
- Communication
- Metabolism
- Repair
20Brain Communication
- Neurotransmitters
- A chemical messenger between neurons that excite
or inhibit.
21Brain Metabolism
- Brain needs lots of blood to nourish cells with
oxygen and glucose. - Or death to cells.
22Brain Repair
- Neurons can live 100 years or more.
- They must maintain and repair.
- Injury and illness can destroy.
- New neurons can be generated in some areas.
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24The Frontal Lobes
- Help you to do more than one thing at once.
- Prioritize what to focus on.
- Sense how much time is passing.
25When dementia affects the frontal lobes, you may
- Have difficulty focusing on a task and paying
attention to what is going on. - Be overwhelmed when a caregiver talks and touches
at the same time. - Have difficulty following the logic of an
argument. - Need the most important words said first in a
sentence.
26You may also
- Need short and simple words and sentences.
- Refuse a bath because you cant think of how to
do it. - Be unable to stop striking or grabbing someone
because you cant control impulses.
27Temporal Lobes
- The temporal lobes help you
- Understand language
- Speak
- Read and write.
28When dementia affects the temporal lobes, you
may
- Make non-sense words.
- Use the wrong sounds when talking.
- Substitute words or use fewer words.
- Say yes when you mean no.
- Not understand what someone tells you.
- Not understand what you read.
- Use swear words without realizing it.
29 Parietal Lobes
- The parietal lobes
- Help you locate and arrange objects in space.
- Tell your brain to pay attention to everything
that is in the space you see.
30When dementia affects the parietal lobes, you may
- Use excessive energy putting an arm into a shirt
sleeve. - Put a glass down on the edge of a plate, rather
than beyond it. - Have difficulty responding to objects on the left
side of your visual field. - Have difficulty tolerating clutter, many objects,
and movement in the room.
31You may also
- Feel angry, frustrated, and tired from all of the
confusing objects and sounds in the environment. - Respond better when a caregiver approaches from
the front. - Resist stepping into a tub or shower because you
cant see the side of the tub, where your feet
or hands should go, or how deep the water is.
32Hippocampus
- The hippocampus creates your memory of recent
events such as - What someone just said.
- What you had for lunch.
- Who just visited you an hour ago.
- Where you parked your car.
33When dementia affects the hippocampus, you may
- Repeat a question over and over again.
- Forget that a family member just visited.
- Be surprised or angry when a caregiver begins to
remove clothing when you just agreed to take a
shower. - Lose items repeatedly or store them in the wrong
place.
34The Aging Brain
35Namenesia
Hi. Im, Im, Im. Youll have to forgive me,
Im terrible with names.
36Roomnesia
Now why did I come in here?
37Fleeting thought syndrome
A.K.A. the senior moment
38Memory loss is not a normal part of aging
39Decline in mental ability is not inevitable as
people age
- Neuroplasticity
- Cognitive reserve
40Cognitive Reserve
- Relationship between brain pathology and
cognitive effect moderated by CR - CR markers education, occupation, leisure
interests - Greater CR causes less impact on function with
similar level of pathology - Greater CR leads to steeper decline once
pathology overwhelms
Yaakov Stern
41Types of Memory
- Episodic memory
- Semantic memory
- Working memory
- Procedural memory
42The Aging Brain
- Brain tissue volume decreases with age due to
white matter loss. - Regional loss may be gender specific.
- Frontal regions are more vulnerable to decline.
- Neurogenesis growth of new brain cells.
43Aging Vulnerable Processes
- Processing speed
- Working memory
- Divided attention
- Complex visual processing
- Long term memory
- Episodic memory
- Source recall
44Preserved Abilities with Aging
- Priming - an unconscious influence of past
experience on current performance or behavior.
45Visual Priming
- C H _ _ M _ _ K
- O _ T _ _ U S
- D _ N O _ _ U R
- P R _ _ T I _ _ _ I T _ _ _
-
46Preserved Abilities with Aging
- Priming - an unconscious influence of past
experience on current performance or behavior. - Inhibition of stimulus-bound responding.
47Stroop test
48Common Causes of Poor Memory
- Insomnia and impaired sleep (apnea)
- Drug side effects (antihistamines)
- Menopause
- Depression
- Attention Deficit Disorder
- Head injury
- Chemotherapy
49Problem Medications
- Antiarrythmics
- Antiemetics
- Antihistamines
- Antiparkinson Agents
- Antipsychotics
- Antispasmotics
- Skeletal Muscle Relaxants
- Tricyclic Antidepressants
50Uncommon Causes of Poor Memory
- Young onset Alzheimers disease
- Mosquito and tick born disease
- Brain tumors
- Toxin and heavy metal exposure
- Anesthesia
- Seizures
51Early Warning Signs of Dementia
- Frequent repeating / defensive answers
- Word finding difficulty
- Mistakes with bills / checkbook
- Changes in hygiene / grooming
- Mistakes with medications
- Geographic disorientation
52Alzheimers Disease
53Alois Alzheimer 1864-1915
54Risk Factors
- Advancing age
- 65 or older
- Mild cognitive impairment (MCI)
- Family history
- Genetics
- Young onset
- Downs Syndrome
55DSM-IV Diagnosis
- Decreased cognitive functioning including
- Memory impairment
- One or more of
- Aphasia
- Apraxia
- Agnosia
- Inability to plan, organize, sequence
- Inability to comprehend abstract concepts
56DSM-IV Diagnosis
- These deficits cause significant impairment in
daily functioning. - Gradual onset and continued decline.
- Not due to other physical or mental medical
conditions or during the course of a delirium.
57The Alzheimer Brain
- Massive cell loss changes the entire brain during
Alzheimers progression. - The cortex shrivels. This damages the brains
ability to think, plan, and remember. - The hippocampus shrivels, which affects the
ability to form new memories. - Ventricles (fluid-filled spaces) grow larger.
58The Alzheimer Brain
- Underneath the microscope
- Alzheimer tissue has less nerve cells and
synapses. - Plaques (abnormal clusters of protein fragments)
build up between nerves. - Dead and dying nerve cells remain in the brain.
- Plaques and tangles are the prime suspects of
cell death and tissue loss.
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61Alzheimers progression
- The early stages of Alzheimers may begin up to
20 years before a diagnosis is made. - Mild to moderate stages last 2-10 years.
- Severe Alzheimers lasts 1-5 years.
62Stages of Alzheimers
- http//www.nia.nih.gov/Alzheimers/Publications/sta
ges.htm
63Vascular Dementia
- Second most common form of dementia.
- Caused by problems with the supply of blood to,
or within the brain.
64Risk Factors
- Hypertension
- Diabetes
- Genetic
65Symptoms of vascular dementia
- May develop suddenly then decline in steps.
- Memory loss may not be the first symptom.
- Concentration problems.
- Changes in mood.
- Physical weakness.
- Difficulty communicating or conversing.
66Types of vascular dementia
- Large stroke (cortical) associated with physical
impairments. - Small stroke (lacune) in the basal ganglia or
thalamus strategic. - Small vessel disease (sub-cortical).
- Intracranial bleed (intracerebral subdural).
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68Dementia with Lewy Bodies
- Discovered in 1912 by Frederich Lewy.
- Common cause of dementia in the elderly.
- Dopaminergic, cholinergic, noradrenergic,
serotonergic, and glutaminergic systems affected,
decreased dopamine D2 receptors. - Over 50 of Parkinsons patients develop PDD
dementiaa Lewy Body dementia.
69Dementia with Lewy Bodies
- May coexist with AD
- 10 to 30 of AD cases have LBs.
- 32 to 89 of DLB cases have AD changes.
- AD pathology in DLB is different, less severe,
more diffuse plaques, rare tangles. - Familial form of DLB associated with triplication
of SNCA gene.
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71Symptoms of Lewy Body Dementia
- Episodes of altered consciousness
- Fluctuating cognition
- Recurrent visual hallucinations
- Parkinsonism
- Extreme sensitivity to anitpsychotics
- Sleep disorders
72Frontotemporal Dementia
- Frontal temporal areas of the cortex are
affectedPicks bodies form and impair neuronal
function. - Fairly common10 to 15 of cases.
- Onsetage 40-65 60 average.
- Can last longer than Alzheimers.
- May be hereditary in 38-60 of cases.
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74The Frontal Lobes
- Help you to do more than one thing at once.
- Prioritize what to focus on.
- Sense how much time is passing.
75Temporal Lobes
- The temporal lobes help you
- Understand language
- Speak
- Read and write
76Symptoms of FTD
- Behavior and personality changes
- Personal and social awareness impaired
- Disinhibition
- Repetitive behaviors
- Fixations/obsessions
- Impulsive
- Hyperorality
77Other Dementia Types
- Wernicke-Korsakoff Syndrome
- Cognitive problems after chemotherapy
- Normal pressure hydrocephalus
- Jakob-Creutzfeld
- Head Injury
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79Dementia Diagnostic Process
80Referrals to a memory program
- You suspect or know that a dementia problem
exists - AND
- you are concerned about patient independence or
ability to manage ADLs at home, - OR
- you are concerned about a caregivers ability to
manage a patient at home.
81Clinical Pearl
- Normal motor examination
- Cognition worse than behavior....... Think
Alzheimers - Behavior worse than cognition....... Think
frontal lobe (Picks) - Parkinsonian signs on examination
- No hallucinations early in illness Think
vascular dementia - Detailed visual hallucinations early
- Think Lewy Body dementia
82Key points regarding diagnosis
- The MMSE is a disorganized, fair quality
screening tool. - The Clock Drawing test has drawbacks and
limitations. - 90 of the diagnosis is based upon collateral
history, which may be inaccurate. - A physical and neurological exam is mandatory.
83Key points regarding diagnosis
- History and examination findings should not be
interpreted in a clinical vacuum. - Few text book situations occur and overlap
conditions are common. - Not everyone with dementia has Alzheimers
disease and some have protracted delirium.
84Benefits of Medical Assessment
- Diagnostic clarification
- Identify medical conditions affecting capacity
- Identify means to enhance capacity
- Identify less restrictive alternatives
- Preemptive planning
85What the health care team must do for the patient
- Give a clear diagnosis and prognosis
- Exude optimism
- Lessen fear and the stigma of dementia
- Prescribe cognition stabilizer(s)
- Inform where resources are located
86What the health care team must do for the
caregivers
- Provide closure
- Exude confidence
- Relieve guilt
- Provide reassurance
- Provide support resources
- Set care giving limits
87Diagnostic challenges
- Less than half of all Alzheimers patients know
that they have the disease. - 2/3 are not diagnosed until they reach the
moderate stage. - Published clinical guidelines to facilitate
diagnosis are infrequently used.
88Diagnostic challenges
- No blood or imaging test can reliably diagnose
any type of dementia. - Most diagnoses are made by neurologists and
neuropsychologists. - Demand will soon exceed their supply.
- Primary physicians will become more responsible
for diagnosing dementia by necessity.
89Misperceptions Clarified
- Alzheimers disease can be accurately diagnosed
in up to 97 of cases using simple assessment
techniques in the office. - New advancements in treatment will make a real
impact in the lives of dementia patients. - It is terrible to have Alzheimers disease and
not know it.
90LTC Rules of Thumb
- AD can be diagnosed in LTC setting.
- Imaging is less important.
- Careful medication review is critical (any
antihistamine, bladder drug, sleeping pill, TCA,
potent analgesic, and measurable drug can
worsen memory and behavior).
91Dementia Diagnostic Process
- Review of symptom onset and progression
- Memory testing
- Physical and neurological examinations
- Blood tests
- Brain imaging
92Mental Status Testing
- Orientation
- Learning and memory
- Three word item recall
- Naming ability
- Name parts of objects
- Gnosis
- Describe function of objects
- Tempoparietal function
- Language comprehension, ideomotor praxis,
left-right discrimination - Visual constructions
- Clock drawing, cube copying
- Working memory
- Add coins
93Mental Status Testing
- Abstraction
- Explain similarities
- Attention and concentration
- Digit span
- Months of the year reversed
- Language
- Fluency, repetition, reading
- Spatial and object memory
- Recall where an item was hidden
- Remote memory
- Details about significant past events
94Common Screening Tools
- Folstein Mini-Mental State Examination
- Montreal Cognitive Assessment Screening (MOCA)
- Mini-Cog
- Functional Activities Questionnaire
- The Seven Minute Screen
- Clock Drawing Test
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96Lab Testing
- CBC, CMP
- B-12
- TSH
- Syphilis testing
- CSF analysis
97Brain Imaging
- CT Scanning
- MRI
- PET Scanning
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100Treatment Modalities
- Pharmacological
- Behavioral
- Palliative not curable
101Realistic Goals of Dementia Treatment
- Attenuate cognitive and functional decline.
- Prevent / decrease behavioral and psychiatric
symptoms. - Delay nursing home placement.
- Lengthen period of self-sufficiency.
- Reduce caregiver burden.
102Pharmacologic Arsenal
- FDA Approved Medications for Treatment of
Alzheimers Dementia - Cholinesterase Inhibitors Prevent the breakdown
of acetylcholine - Donepezil (Aricept), Galantamine (Razadyne),
Rivastigmine (Exelon) - Glutamate Regulator
- Memantine (Namenda)
103Pharmacologic Arsenal
- Medications for the treatment of mood disorders
and behaviors - Antidepressants
- fluoxetine, citalopram, mirtazepine, sertraline,
venlaxafine - Antipsychotics
- haloperidol, risperidone, quetiapine,
zasperidone - Anxiolytics
- buspirone, lorazepam
104Other Therapies
- Dynamic psychotherapy
- Aromatherapy
- Music therapy
- Phototherapy
- Electroconvulsive therapy
105Prevention of Dementia
- Stay mentally and physically active
- Socialize
- Live a healthy lifestyle
- Eat a balanced diet
106Working with clients who have dementia
- Behaviors of Dementia
- Behavior Management
107Cognitive changes
- These are changes in memory, thinking, and
learning. - Involve a variety of mental skills such as
attention, problem-solving, memory, language ,
visual-perceptual skills, and other aspects of
reasoning and intellect.
108Dementia can cause difficult behaviors
- Changes in the brain can cause problems with a
persons ability to think, understand, and
respond appropriately. - The behaviors result from the disease itself, not
because the person is trying intentionally to be
mean or uncooperative.
109Dementia Behaviors
- Repetitive questioning or hoarding/obsessive
behavior - Poor judgment
- Disinhibition
- Impulsiveness
- Wandering
- Insomnia or somnolence
110Dementia Behaviors
- Irritability, agitation, restlessness, aggression
- Social withdrawal, apathy, depression, suicidal
ideation - Hallucinations-sensory
- An object or event is believed to be perceived
- Delusions-thoughts
- Untrue beliefs based on pathology
- Paranoia and unfounded accusations
111Prevalence of dementia
- The reported dementia prevalence in Assisted
Living and Special Care Units ranges from 40-67. - Dementia afflicts a substantial portion of
elderly patients on the medical-surgical units of
general hospitals. - ALFA (2006) Lyketos, Sheppard, Rabins (2000)
112Prevalence of behavioral symptoms
- 56 of residents in AL settings had behavioral
symptoms related to dementia. - Current management methods are insufficient to
respond to the needs of residents. - Boustani and associates (2005)
113Challenges of dementia
- Functional challenges
- Personality changes
- Mood changes
- Resistance
- Lack of Insight
- Apathy
- Shadowing
- Repeating
- Agitation
- Aggression
- Paranoia
- Wandering
- Delusions
- Hallucinations
114Framework for care
- Provides for person-centered planning.
- Organizes the many theories, approaches,
strategies, and techniques. - Comprehensive assessment.
- Maximize functional independence and morale of
individuals with dementia.
115The Habilitation Domains
- The top 3
- Physical
- Functional
- Emotional
116The Habilitation Domains
- Social
- Sensory
- Communication
117The Five Tenets
- Tenet 1
- Make the physical environment work.
- Tenet 2
- Know that communication remains possible.
- Tenet 3 Focus on remaining skills.
118The Five Tenets
- Tenet 4
- Live in the patients world behavioral changes.
- Tenet 5 Enrich the patients life.
119Link behavior to an unmet need.
- Link the behavior to one of three human needs
- Love
- Usefulness
- Expression of raw emotions
120Look at behavior as a means of communication.
- What is the person trying to communicate?
- Is it worth responding to or is it simply
annoying? - Pick your battles.
121What happened before?
- To help determine reasons for a patients
behavior, look at its antecedents.
122Sudden behavior changes
- May indicate relationship issues.
- May indicate medical or physical problem.
- May indicate environmental change.
123Assess for delirium
- Abrupt state of confusion
- Disturbance of consciousness
- Impairment of cognition and perception
- One or more underlying causes
- May be associated with hyperactivity or lethargy
124Symptoms of delirium
- Many types of cognitive - behavioral symptoms can
occur including visual hallucinations, delusions,
paranoia, manic behavior, aggression, apathy, and
impaired memory. - Sun-downing is not specific to delirium.
125Risk factors for delirium
- Severe illness
- Hypo perfusion
- Hypoxia
- Infection
- Drug toxicity
- Fractures
- Alcoholism
126Risk factors for delirium
- Dementia (25-50 of all cases)
- Impaired ADLs
- Sensory impairment
- Urinary retention
- Fecal impaction
- Physical restraint use
- Sleep deprivation
127Assess for pain
- Ask the resident.
- Interview the caregivers.
- Review the medical record for pain-related
diagnoses. - Physical examination and lab studies.
128Assess for pain
- Use a validated pain rating system
- Facial expression
- Posture
- Vocalizations
- Appetite
- Interactivity
129Pain Rating Scales
- Verbal 0-10 scale
- Abbey pain scale
- Pain assessment for the dementing elderly
- Faces Pain scale
- Pain assessment in advanced dementia (PAINAD)
- Checklist of nonverbal pain indicators CNPI)
130Evaluate the consequences
- Do the behaviors need to change for the comfort
and the safety of the patient or the caregiver? - Some behaviors do not bother the patientdo they
need to be modified?
131Set the tone
- Relax. Center.
- Use a clear, low, loving tone of voice.
- Calm, gentle, matter-of-fact approach.
- Humor.
- Cheerful.
132Set the tone
- Use the mirroring technique.
- Chat about a happy topic before starting a task.
- Use short, simple sentences, familiar words.
133Build trust
- Use non-threatening, factual words who, what,
when, where, and how. - Avoid asking why something happened or why they
did something.
134Do not attempt to reason
- People with dementia lose their ability to
reason. - Insight is often impaired.
135Rephrasing
- The individual is validated/comforted when their
own words are acknowledged by another. - Repeat the gist of what the person has said,
using the same key words. - Use a similar tone and cadence.
136Use redirection to stop undesired behavior
- Can the patient be distracted with another
activity, treat, topic of conversation? - You may have to say, Now we are going to
rather than asking or suggesting a task or
activity.
137Reminiscing
- Exploring the past can help re-establish familiar
coping methods and ways of handling stress. - Use always and never to trigger earlier
memories.
138Easier to change the environment
- Under stimulation
- Restlessness, pacing, wandering, or calling out.
- Over stimulation
- Nervousness, agitation, physical aggression.
139Progressively Lowered Stress Threshold Concept
(PLST)
- A proactive intervention to reduce likelihood of
challenging behaviors. - Based on premise that those with dementia have a
decreased ability to respond to stressors. - The cumulative effect of stressors prompts
behaviors.
140Stabilize the environment
- Routine daily schedule.
- Create a level of quiet and peace.
- Make sure the patient is comfortable.
141Maximize sensory input
- Validate the patients reality without
exacerbating anxiety - Keep simple, but provide multi-sensorial
opportunities - Music
- Fabrics, pets
- Touch
142Identify and Use the Preferred Sense
- Enables caregiver to speak the persons language
and improve communication. - Builds trust.
- Vision
- Hearing
- Touch
- Smell
143Touch
- Confused individuals often need to feel the
presence of another human being. - Pleasant memories are often evoked.
- Personal space must be respected.
144Music
- When words are gone, melodies return.
- Comforts, reduces agitation and stress.
- Provides channel for expression of emotion.
- Enhances communication.
145Consider life experiences
- Former life experiences can play a major role in
behavior. - At times, thinking of the persons former role
may help in the development of activities.
146Need for staff training is critical.
- Staff who are trained in dementia and its
management are better prepared to care for
residents. - But, nearly 88 of resident assistants thought
that confusion was a normal consequence of aging.
- Hawes and Phillips (2000) Luxenberg (2003),
Alzheimers Association (2005).
147Education and training will be key
- Growing elderly population.
- Projected nursing workforce shortage.
- Rates of staff turnover are likely to increase.
- Retention of adequate staff will become even more
difficult in the future. - Callahan, 2001 General Accounting Office GAO,
2001 Noelker, 2001, Stone, 2001.
148Awareness of Abuse
- A closer look at agitation/aggression
149Abuse
- Physical, psychological, sexual, and/or financial
maltreatment, that may be the result of the
actions of others or may result from neglect by
others or by self. - (Dyer et al., 2000).
150Prevalence of elder abuse
- All forms are under-reported
- 1 to 4 all elders
- 5.4 to 11.9 for demented elderly
151Risk factors for elder abuse
- Excessive physical and psychological demands
associated with care giving - Advanced age
- Poor health and physical frailty
- Impaired activities of daily living
152Risk factors for elder abuse
- Alcohol and substance abuse
- Psychopathology
- History of abusive behavior
- Poor pre-morbid relationships
153Risk factors for elder abuse
- Families caring for relatives with Alzheimers
Disease in the community are particularly
vulnerable to episodes of violent behavior. - Caregiver depression
- Living arrangement with immediate family member,
but not spouse - Paveza, Cohen, et al. The Gerontologist, 1992
154Abuse from care recipients
- 57-67 of dementia patients manifest some form of
aggressive behavior. - Nearly 16 patient to caregiver violence.
- In one study, 66.2 of nursing home assistants
reported minor physical injuries on a daily
basis, with 58.2 experiencing more serious
injury in last 12 months.
155Neuroanatomy of Aggression
- Many areas of the brain are involved
- Prefrontal cortices (trouble thinking)
- Left temporal lobe (short fuse)
- Limbic system (anxiety moodiness)
- Hypothalamus
- Amygdala
- Brainstem
156Neurophysiology of Aggression
- Complex interplay of neurotransmitters and
hormones - Serotonin
- Norepinephrine
- Testosterone
157Diagnose the cause of agitation
- Infection
- Injury
- Pain or discomfort
- Illness physical, psychiatric
- Sleep disorders
- Medication side effects or interactions
- Environmental triggers
- People triggers
158Prevention of agitation or aggressive behavior
- Address the causes or antecedents
- Provide a structured environment
- Provide appropriate activity
- Address emotional needs
- Modify caregiver communication techniques and
approaches - Provide sunlight
159Treatment of agitation and aggression
- Behavioral
- Pharmacological
160Behavioral treatment of agitation and aggression
- Identify the level of agitation and respond
accordingly. - Mild validate and talk.
- Moderate structure environment distract.
- Severe establish understandable limits decrease
stimuli.
161Behavioral treatment of aggression
- Panic Phase
- Intervention is needed to prevent injury.
- Get away (pre-planned exit strategy).
- Obtain assistance.
162Rescue
- 911
- Facility code-response team
163Psychiatric Hospitalization
- Careful consideration.
- Behavioral and pharmacological treatment first.
- Goal is to eliminate aggressive symptoms and
return to his/her environment.
164Medications to treat agitation and aggression
- No medications are approved by the FDA for the
specific treatment of aggression. - Medications that are used must be monitored to
determine effectiveness.
165Medications
- SSRI Antidepressants
- Used to treat lowered serotonin levels.
- sertraline, fluoxetine, citalopram, escitalopram,
etc. - Some effect can be noted in 3 to 5 days, but can
take two weeks for full effect. -
166Medications
- Beta-blockers propranolol, metropolol
- Antipsychotics Risperdal, Haldol, quetiapine
- Anti-convulsants valproate, Tegretol, Neurontin,
Lamictal - Combination therapy, such as
- buspirone propranolol
- valproate anti-psychotic medication
167About those benzodiazepines
- Medications, such as Ativan and Xanax, are used
for anxiety in non-demented patients - When used with demented patients, they can
increase confusion, falls, and agitation. - Limit to an as needed basis only.
- Avoid gels.
168When to report to APS
- When the caregiver is unable to protect self
and/or the care recipient from elder abuse. - Other interventions have been unsuccessful.
169Recommendations
- The likelihood of aggressive behaviors needs to
be an expectation among the demented and mentally
ill population. - Improved recognition and assessment.
- Education and training.
- Improved reporting.
170Case Management and Care Coordination
- Each case is unique.
- It is never just about the patient.
- Case management interventions must be directed at
the patient and his/her caregiver(s).
171Outpatient Case and Disease Management
- Case Management Process
- Engagement
- Assessment
- Plan of Care Collaboration
- Intervention
- Evaluation
172Assessment for Intervention
- Due to changes in the brain from dementia, a
person needs the environment and the caregiver to
compensate for impaired memory functions. - The more we know about how a persons memory
ability has changed, the more we can target
successful strategies to improve their quality of
life.
173Engagement
- With whom will you be working?
- Size up family dynamics.
- Capacity/insight issues.
- Medical decision-making.
- Recognizing and responding to caregiver stress.
- Empathetic approach.
174Assessment
- Biopsychosocial
- Active listening approach
- Assess ability/stress of care provider
175Assessment
- Patient Goals
- Caregiver Goals
- Long term care plans?
- Existing Strengths and Resources
- Medical Record
- Reassess at 6 months
176Tools for Assessment
- Case management organizations
- Biopsychosocial assessment tools via internet
- Katz activities of daily living
- Create a short form
177Plan of Care Collaboration
- Patient
- Caregiver(s)
- Medical providers
- Community resources
178Interventions
- What is needed to keep patient safe?
- What will provide for patients dignity?
- What will improve patients quality of life?
- What offers least restrictive environment?
179Interventions
- What communication techniques and behavioral
approaches will be most effective? - What is needed to support the caregiver?
180Interventions
- Medication management
- Financial security
- Environmental adjustments
- Personal care assistance
- Nutrition/hydration
- Physical exercise
- Social activities
- Caregiver support
181Interventions
- Identify key agencies
- Alzheimers Association others
- Area Agency or Commission on Aging
- Senior Neighbor Centers and Service
- Social Security Administration
- Veterans Administration
- Secretary of State
- MDCH
- Medicare Medicaid
182Interventions
- Identify Home Supports
- Adult day programs
- Home delivered meals
- Home helper services
- Respite care
- Transportation
183Interventions
- Assist with long-term care planning
- DPOA or guardianship
- Housing advisors
- Long term care facilities
- PACE
- AL
- AL dementia
- Skilled nursing facilities
- Hospice
184The Alzheimers Disease Bill of Rights
- To be informed of ones diagnosis.
- To have appropriate medical care.
- To be productive in work and play for as long as
possible. - To be treated like an adult, not a child.
- To have expressed feelings taken seriously.
185The Alzheimers Disease Bill of Rights
- To be free from psychotropic medications, if
possible. - To live in a safe, structured, and predictable
environment. - To enjoy meaningful activities that fill each
day. - To be outdoors on a regular basis.
186The Alzheimers Disease Bill of Rights
- To have physical contact, including hugging,
caressing, and hand-holding. - To be with individuals who know ones life story,
including cultural and religious traditions. - To be cared for by individuals who are well
trained in dementia care. - The Best Friends Approach to Alzheimers Care, by
Virginia Bell and David Troxel 1997 Health
Professions Press, Inc., Baltimore
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