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PubMed????

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Title: PubMed????


1
PubMed????
?????????? ???
2
????
  • ??PubMed?NCBI???????
  • ??PubMed??????PubMed?????
  • ??PubMed?????????????
  • ??PubMed Central

3
PubMed????????
  • NCBI(National Center for Biotechnology
    Information,????????????)
  • NCBI????????????????????,????????????????Claude
    Pepper?????????????????????,??,?1988?11?4???NCBI?N
    CBI?National Institutes of Health(NIH)???National
    Library of Medicine(NLM)????????NLM???????????????
    ?,????NIH???,??????????????NIH??????????????????
  • NCBI????????
  • ??????????????,?????????????--DNA?????????????
  • ??????????????????????????, ??????????????????????
    ?????? ????????????????????????????
    ????????????????????,?????????????????
  • NCBI?????
  • NCBI????????,???Computational Biology Branch
    (CBB)?Information Engineering Branch(IEB)?Informat
    ion Resources Branch(IRB),?????????????

4
NCBI?????
  • Computational Biology Branch(CBB)
  • ???????????????????????????????,??????????????????
    ???????????????????/??????
  • ??NIH?????????????????????????????????????????????
    ???????
  • ???????????????????
  • ?????????,??????????????????

5
NCBI?????
  • Information Engineering Branch(IEB)
  • ??????????????,???????????????????????????????
  • ??????????????????????,??????????????
  • ????????????,?????????????????
  • ?????????????????,????????????????????
  • ??NIH????????????????????
  • ????????????????
  • ??????????????????????

6
NCBI?????
  • Information Resources Branch(IRB)
  • ????????NCBI????????,????????????????????????
  • ??NCBI?????????????
  • ??NCBI??????????
  • ????NCBI????????????
  • ??????????????????,?????NCBI??
  • ?????????
  • ?????????????????????
  • ?????????,?????????,???????
  • ?????????????,???NCBI??????????
  • ????????????????,??NCBI????????

7
NCBI?????
  • NCBI??????????????,???????????????????????????????
    ??,???????????????????????????????????????????????
    ????,???????????????????????????????????(Pattern)?
    ????????HIV???????????????????????????????????????
    ??????????????????????????????????????????????????
    ?(Vector)????????,????????NIH?????????????????????
    ?????????????,?????????????????

8
NCBI??
  • NCBI???????????????
  • ?????
  • ??????

9
NCBI??
  • ?????
  • ??????????????????,???????????????????????????????
    ??,??????????????????????????????????
  • NCBI???????????-Entrez,????????????????????????Ent
    rez????????????????,?????????????????????????,NCBI
    ?????(Open Access)???????

10
(No Transcript)
11
Entrez??BLAST
  • Entrez?NCBI?????????????,??,??,??????????????Entre
    z???????????????????Entrez???????NCBI?????????????
    ?????????????,????,?????,????,???PubMed???MEDLINE?
    Entrez???????????????????,??,???????????????PubMed
    ??,PubMed?????????,??????MEDLINE????????????,?????
    ?????????????????
  • BLAST???NCBI???????????,?????????????????BLAST????
    ?15????????DNA??????????NCBI???????????????????(O
    RF Finder),??PCR,???????,Sequin?BankIt????NCBI????
    ???????WWW?FTP????NCBI??E-mail???,????????????????
    ??????????

12
Entrez????????
  • Books ??????????????????????
  • Cancer Chromosomes ??????????Mitelman Database
    of Chromosome Aberrations in Cancer??????????cytog
    enetic??????????
  • Conserved Domain Database(CDD),??????????????
  • 3D Domains,?????????????
  • Gene,????????????
  • Genome,????800??????????
  • GENSAT,??????????????
  • GEO Datasets,?????????????????
  • GEO Profiles,??????
  • HomoloGene,?????????
  • Journals,????(??PubMed)
  • MeSH,?????????
  • NCBI Web Site,??NCBI??
  • NLM Catalog,???????????????????????
  • Nucleotide sequence database,???????(??GenBank?Ref
    Seq?PDB????????)

13
Entrez????????
  • Online Mendelian Inheritance in Man
    (OMIM),?????????????
  • PopSet,????????????
  • Protein sequence database,????????(??Swiss-Prot?PI
    R?PRF?PDB??????GenBank?RefSeq??????????????)
  • PubChem BioAssay,?????????????
  • PubChem Compound,?????????
  • PubChem Substance,??????????????
  • PubMed,?????????
  • PubMed Central,???????????
  • Site Search,???NCBI????FTP
  • SNP,??????????(dbSNP)
  • Structure,??????(MMDB)
  • Taxonomy,????????????????
  • UniGene,??unique???????
  • UniSTS,unique?????????

14
PubMed????
  • ????????????????????????
  • ??
  • ?????????
  • ??????????(??????)
  • ???????????
  • ???????

15
PubMed????
  • MEDLINE
  • 4800????????,?????????????????????????????????????
    ????????70????????
  • ????1?2??????,????1966??
  • ????indexed for MEDLINE????
  • ? ??2006?3?15?PubMed?????

16
  • In process citation
  • ??MEDLINE???????????
  • ?MeSH??,???MEDLINE?
  • ????in process?????

17
  • Publisher Supplied Citations
  • ??????PubMed??????
  • ??MEDLINE????????
  • ????PubMed-as supplied by publisher?????

18
  • OldMedline
  • 1950-1965?????200?????
  • ??MeSH?????
  • ????PubMed-OLDMEDLINE for Pre1966?????

19
  • PubMed not Medline
  • PubMed ??Medline???????
  • ????PubMed?????

20
PubMed?MEDLINE???
  • ?????
  • MEDLINE?????????????????????(?????????)
  • ?????
  • ?MEDLINE??????????
  • ?????
  • ????????(????)

21
????
PubMed??
???????
??????? ????
????????????????????????????????
22
PubMed ??????
  • ???????
  • ????????(???????AND??)?placenta growth oxygen
    genbacev o
  • ????,???,???????
  • ? smith ab
  • ??????MEDLINE?????????
  • ?clin exp immunol
  • ??????? (??????)
  • ? Stem ti AND neuroscience

23
??????? Moore AM?????????????
24
????? (???????SO)
25
???? moore amau
26
??????
?????????
27
PubMed ??????
  • ????treat
  • ??????brca 1(?????????????)

28
PubMed ??????
  • ???????
  • (automatic term mapping)
  • ????????,????,??,?????, ?????
  • ??????
  • ????
  • ?????????????????????

29
  • ???stemti AND neuroscience
  • Details??
  • stemti AND (("neurosciences"TIAB NOT
    MedlineSB) OR "neurosciences"MeSH Terms OR
    neuroscienceText Word)

30
  • ??????
  • ???????????????????,???hypertension
    therapy,??????????????????,

31
PubMed?????
  • Limits(??????)
  • ???????????????(filter?????)?
  • ??????????????1950?,????30?-10?
  • 7???????
  • 7?????
  • 12????(01???2?Space Life Sciences and Bioethics
    )

32
?????
  • ????
  • ???????(asthma, drug therapy)
  • asthma/drug therapy
  • ??????(hand injuries, surgery, therapy)
  • hand injuries/surgery OR hand injuries/therapy
  • ??????????(aspirin, therapeutic use, myocardial
    infarction, drug therapy)
  • aspirin/therapeutic use AND
  • myocardial infarction/drug therapy

33
?????
  • ???
  • ??????????(tongue neoplasms, pathology, tongue
    base, base of the tongue)
  • tongue neoplasms/pathology AND (tongue base OR
    base of the tongue)

34
?????
  • ????
  • ??????????
  • Wen ymau
  • ?? Jhon Adorn Williams ?????
  • Williams JAAU
  • ????????
  • englishla AND reviewpt

35
PubMed??????
?? ???????? ?????????? ??? ???? ?????? ??? ??????
??? ??? ???? ?????? ??????
36
?????? ?????? ????PubMed?? ???? ?????? ?????? ????
??? ??????????? ?????? ???? ???? ??? ????? ??????
??????? ??????????? ????
37
?????? ????? ??????? ??????? ????? ?????????? ????
????? ????? ?????????? ??????? ????? ????????? ???
?? ???????
38
?????????? ???? ???? ????(?????)
????? ?????? ???????? ???????? ???? ???????? ???
?? ???????? ????????????????????? ???? ???????????
???
39
????
????
?????????
????????
?????????
????
????????????
????
40
??????
??????
???? ?/????
????????
????
?????
??????
????????
41
??????
????
??????
42
Previw/index(??????)
  • ?????
  • ?????
  • (???????1 OR 2)
  • ????(index)

43
????
????
??????
44
Index(?????)
  • ??????
  • ?????(??)
  • ??????????
  • ???????????
  • ??GO

45
??1 ???????
??2 ?????
??4 ????????????????
??3 ????
46
History(???)
  • ?????
  • ?????
  • ?3 AND child

47
??????
???
????
????
??????????????????5 AND 6
48
Details (????)
  • ???????????????
  • ??????????
  • ?liver cancer -gt liver neoplasms
  • ??????

49
????
???????
?????
??????????
50
???????
???
???????
51
??????
  • ????????
  • Limit ? Preview/index? History?
    Details?????

52
?.????
  • Mesh Database
  • ??
  • ???????
  • ????????????
  • ?????????????
  • ????????????????

53
????????????
54
??????????????
55
MeSH Database ???????????????????
1.?????
2.????
3.???????????
56
?????
??????
???????????
????????
57
??????????????
???????????????????
58
????????
??MeSH Database ?????,??41?????
59
  • ????????FK506??????????(????
  • 1?,??,??)


60
  • ????
  • ??????? ????
  • FK506 adverse effects
  • kidney transplantation
  • ??MeSH Database Mesh??
  • ??????? go

61
FK506
MeSH Database
62
??? ?????? ?????? ?????? ??????

63
?????
?????
??????
64
??? ??????(????????????????????????????????)
????????? ???????? send to
65
??????
??????
p175
???????
???????
??????
????
?????
66
???
???
???
????
????
????
????
67
?????? Search Box with AND Search Box with
OR Search Box with NOT
68
??? search box ?? search PubMed
????
69
search box
Tacrolimus / adverse effectsMeSH
70
1251?
1194?
BMJ 2005 Mar 5 330(7490) 516
??????
71
????
Free full text
72
Abstract
73
Methods
Results
74
Discussion
75
??? Limits ?????? (??????????????????
???????) ????
76
??? ?????????? ???????
history ????(??)(AND OR NOT)
????
77
???? (7 AND 10)
78
19?
79
(No Transcript)
80
  • Pubmed????????
  • ????????????
  • ?????? ,??????
  • ????,??????
  • ??????,????,?????
  • ?????,??????

81
  • ?????(Citation Matcher)
  • ??????,???????????
  • ?????,?????
  • ??????????
  • ???Taiwan I Hsueh Hui Chih?Chang PY(taiwan yi
    xue hui za zhi ) ??? 1975 ?????????

82
??????
????????
??????(????????,????????????
83
??????
84
  • ?????(Journal database)
  • ???????????????????
  • ???????????

85
???????
86
???????immunology???
Journals Database
p178
87
110?
111?
88
(No Transcript)
89
??Med Pediatr Oncol????,????????????
90
??Med Pediatr Oncol??
91
(No Transcript)
92
Medical and Pediatric Oncology
???? 1975
p179
93
  • ????????
  • ???????links to full-text web
    sites,???PubMed?????????,??????????????????Pubmed?
    ??????????????????????
  • ???????????

94
????????
95
241 providers,5300 journals
2006.10.6
96
?????
Science
EBSCO HighWire press Infotrieve Ovid
CSIRO EBSCO HighWire Press Infotrieve Ovid
Technologies ProQuest
??????????
p180
97
  • ????(Clinical Queries)
  • ???????????(????)??,????????????????????,???????,?
    ???(????)????(????)?

98
  • ????(Clinical Alert)
  • 1991???,NIH???????????????????????????????????????

99
?.??????
  • ??????
  • ??????
  • ??????
  • ??????

100
??????(Display)
  • Abstract report????????????????????????????????P
    MID?UI????
  • Citation Report ????????,?MeSH???????????????????
  • MEDLINE Report (???,????)

101
??????
102
??????
  • ????????
  • ?????display????,????????
  • ???? ?????

103
?????????
104
??????(send to)
  • ????(???)?
  • Text????????,????????
  • File???????????,??????
  • Clipboad ???,???????,?????????? ??????500?,??8???
  • Email ??????
  • RSS Feed?????RSS??,??????????????????,???????
  • Other?????????,??????

105
(No Transcript)
106
Send to text
107
Send to file
108
Send to E-mail
109
Send to order
110
LINKOUT
111
??????
  • Details ??URL ,?????????????????,????????????????
    ?
  • My NCBI(Cubby)?????????,?????????????

112
??????
  • 1 ?????(???????)
  • 2 show???,??????????
  • 3 ???????(word)

113
?.?????????
  • ??????( linkout,???????,PMC )
  • ?NLM????(order)(????????????)
  • ??????(related article)
  • ???????(??????)

114
??????????
115
(No Transcript)
116
(No Transcript)
117
Linkout??
118
??????
119
???OVID??
120
PMC (PubMed Central)
  • ??????????
  • ????130?????10?????
  • (???PubMed??????)

121
(No Transcript)
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