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The Trematodes

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Fasciola hepatica in bile duct Fasciola hepatica adult Egg of Fasciola hepatica . Title: PowerPoint Presentation Author: USER Last modified by: Dr.AlKhalifi – PowerPoint PPT presentation

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Title: The Trematodes


1
The Trematodes
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Developing schistosome in liver
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Eggs of Schistosoma mansoni
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Eggs of Schistosoma mansoni in the liver
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Cellular reaction around eggs of Schistosoma
mansoni
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Egg of S. haematobium
Schistosomaiasis granuloma
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Schistosomaiasis granuloma
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Pathology of Schistosomiasis
  • Schistosoma haematobium
  • Causes urinary schistosomiasis
  • PREPATENT PERIOD 10-12 wks
  • EGG DEPOSITION AND EXTRUSION
  • painless haematuria
  • Inflammation of bladder and burning micturition
  • TISSUE PROLIFERATION AND REPAIR
  • Fibrosis , papillomata in the bladder and lower
    ureter leading to obstructive uropathy.
  • Periportal fibrosis
  • Lung and CNS involvement
  • Schistosoma mansoni
  • Causes intestinal schistosomiasis
  • PREPATENT PERIOD 5-7 wks
  • EGG DEPOSITION AND EXTRUSION
  • dysentery (blood and mucus in stools),
  • hepatomegaly splenomegaly
  • TISSUE PROLIFERATION AND REPAIRFibrosis ,
  • Papillomata in intestine,
  • Pperiportal fibrosis,hematemesis
  • Lung and CNS involvement.

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Schistosome dermatitis, or "swimmers itch occurs
when skin is penetrated by a free-swimming,
fork-tailed infective cercaria. Source WikiMedia.
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Bladder lesions in urinary schistosomiasis
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Hepatosplenomegaly in chronic schistosomiasis
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Portal hypertension in chronic schistosomiasis
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Portalsystemic anastomoses
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Diagnosis of Schistosomiasis
  • Schistosoma haematobium
  • Parasitological
  • Examination of urine
  • Immunological
  • Serological tests
  • Indirect
  • Radiological
  • Cystoscopy
  • Schistosoma mansoni
  • Parasitological
  • Examination of stools
  • Immunological
  • Serological tests
  • Indirect
  • Radiological
  • endoscopy

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Egg of S. haematobium
Egg of S. japonicum
Egg of S. haematobium
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Egg of S. mansoni
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Drug of choice for schistosomiasis isPraziquantel
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Life-cycle of Fasciola hepatica
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Snail intermediate host of Fasciola hepatica
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Watercress , one means of transmission of
fascioliasis
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Fasciola hepatica
Fasciola hepatica
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Fasciola hepatica
  • Pathology and clinical picture
  • True infection causes mainly biliary obstruction
    and liver damage .
  • False infection is when eggs are eaten in
    infected animal liver and passed in stools.
  • Diagnosis eggs in stools or duodenal aspirate.
  • Treatment Triclabendazole.

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Fasciola hepatica adult
Fasciola hepatica in bile duct
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Egg of Fasciola hepatica
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Triclabendazole is the drug of choice to treat
fascioliasis and is on the WHO list of essential
medicines. The correct dosage is calculated based
on the persons weight (10 mg/kg) and the tablets
are given at one time.
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Sheep liver infected with Fasciola hepatica
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Fasciola hepatica spurious infection
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Fasciola hepatica spurious infection (eggs in
stools)
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