Title: The Trematodes
1The Trematodes
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4Developing schistosome in liver
5Eggs of Schistosoma mansoni
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7Eggs of Schistosoma mansoni in the liver
8Cellular reaction around eggs of Schistosoma
mansoni
9Egg of S. haematobium
Schistosomaiasis granuloma
10Schistosomaiasis granuloma
11Pathology of Schistosomiasis
- Schistosoma haematobium
- Causes urinary schistosomiasis
- PREPATENT PERIOD 10-12 wks
- EGG DEPOSITION AND EXTRUSION
- painless haematuria
- Inflammation of bladder and burning micturition
- TISSUE PROLIFERATION AND REPAIR
- Fibrosis , papillomata in the bladder and lower
ureter leading to obstructive uropathy. - Periportal fibrosis
- Lung and CNS involvement
- Schistosoma mansoni
- Causes intestinal schistosomiasis
- PREPATENT PERIOD 5-7 wks
- EGG DEPOSITION AND EXTRUSION
- dysentery (blood and mucus in stools),
- hepatomegaly splenomegaly
- TISSUE PROLIFERATION AND REPAIRFibrosis ,
- Papillomata in intestine,
- Pperiportal fibrosis,hematemesis
- Lung and CNS involvement.
12Schistosome dermatitis, or "swimmers itch occurs
when skin is penetrated by a free-swimming,
fork-tailed infective cercaria. Source WikiMedia.
13Bladder lesions in urinary schistosomiasis
14Hepatosplenomegaly in chronic schistosomiasis
15Portal hypertension in chronic schistosomiasis
16 Portalsystemic anastomoses
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18Diagnosis of Schistosomiasis
- Schistosoma haematobium
- Parasitological
- Examination of urine
- Immunological
- Serological tests
- Indirect
- Radiological
- Cystoscopy
- Schistosoma mansoni
- Parasitological
- Examination of stools
- Immunological
- Serological tests
- Indirect
- Radiological
- endoscopy
19Egg of S. haematobium
Egg of S. japonicum
Egg of S. haematobium
20Egg of S. mansoni
21Drug of choice for schistosomiasis isPraziquantel
22Life-cycle of Fasciola hepatica
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25Snail intermediate host of Fasciola hepatica
26Watercress , one means of transmission of
fascioliasis
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30Fasciola hepatica
Fasciola hepatica
31Fasciola hepatica
- Pathology and clinical picture
- True infection causes mainly biliary obstruction
and liver damage . - False infection is when eggs are eaten in
infected animal liver and passed in stools. - Diagnosis eggs in stools or duodenal aspirate.
- Treatment Triclabendazole.
32Fasciola hepatica adult
Fasciola hepatica in bile duct
33Egg of Fasciola hepatica
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35Triclabendazole is the drug of choice to treat
fascioliasis and is on the WHO list of essential
medicines. The correct dosage is calculated based
on the persons weight (10 mg/kg) and the tablets
are given at one time.
36 Sheep liver infected with Fasciola hepatica
37 Fasciola hepatica spurious infection
38Fasciola hepatica spurious infection (eggs in
stools)