?????????? ???????????? ?????????? ???????? ?? ???????? ????: ???????????? - PowerPoint PPT Presentation

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?????????? ???????????? ?????????? ???????? ?? ???????? ????: ????????????

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Title: ?????????? ???????????? ?????????? ???????? ?? ???????? ????: ????????????


1
??????????? ?????????? ??????-??????????
???????????????? ??????? ?.?.
????????????????? ??? ? ?????????????
???????
???????
  • ?????????? ?????? ? ?????????????
  • ???????? ???????????? ??? ??????? ? ??????????
    ??????? ????????? ? ???????????? (????????????? ?
    ???????????, ?????????? ????????? ??????????? ?
    ??.)
  • ?????????? ???????????? ?????????? ???????? ??
    ???????? ???? ???????????? ????????-2,
    ????????????? ????-??? ??????????? ? ??????
    ???????

2
??????????? ?????????? ?????? ? ?????
??????????? ??????????????
????????
?????????????
??????????????
??????????
??????? ????????? ????????? ?????????? ???????
q (4p/?)sin(?/2) ????? ????????? R 1/q
k1 q
?
ko
???????????? "????????" 1 ????????
?????????, ???????? ? ???????? ???????
????????????? 2 ????????????? ??????
????????????? 3 ???? ??????? 5
2D-???????? ???????????? ? ????????? ????? 6 ??
????????? ???????? 4 7 ?????????
3
??????????????????? ????? ????????????
??????????
1 - ??????? ??? 2 - ?????????? ???????????????
?????????? ???????? 3 - ??????? ?????? 4 -
?????-????????? ??????????? ?????????? ?????????
????????? IN4 5 - ????-??? ??????????? SEM 6 -
RTOF-???????????? 7 - SANS "????????"
4
D?-4
???? ???
???? ???????
S-4
D?-5
? ????? ??????
S-1
S-1
????????
S-5
S-2
S-6
3-??? ??
IN-5
R-4
UNISON
??? ???
???? ???????????? ??????-??????????????????
?????????????????? ???????????? ?? ???????
 0,5
5
????????????-??????????????? ???????????????????
???????? ??? ?????????? ??????-?????????? ?
??????????????????? ???????????? (???????????
??????? ? ???????? ??????-??????????????????
??????????? ????????? ??? ?? 23 03. 2008
?.)   ???? ??????? ???????? ????????????? ?
??????????????? ???? ??? ??????????? ??????????
?? ????????, ???????????? ? ????????? ?????
?????????? ?? ?????? ????????? ???????????? ?
?????????? ? ???????????? ??????????? ????????? ?
?????????? ???????? ??????????????? ?
???????????? ??????????? ???????????? ???????? ??
?????? ??????????, ????????????????????? ?
?????????? ? ?? ??????????? (? ?????????,
???????????????) ??? ????????????? ????? ?
???????, ? ?????? ????? ??????????????????? ???
???????? ? ????????
6
???????? ?????????????? ???????????? - 41.5
???. ???. ???????????? ???????????????
???????????? 52.3302 ???. ???. ??????
????????? ??????? - 93.8302 ???. ???.
S3-MICROBridging the Gap to Synchrotrons
7
??? ???? ????????? ???????? ? ???
(???????????????? ?????) ????? ????? ????????
(????????) ????????? ??????????
?????????? ??????? ??????? ????????????
??????????? kT. ??????-??????????
???????????? ???????? ??????? - ????????
???????? ????? ???????? ???????? 10-1
102 ?? ??????? - ?????????? ????????????
??????????????? ??????-?????????? ????????
???????? ??????? 10-9 100 ?? ????????? ???????
??????? ??????? - ??, ??? !!! ?????????????
???????? ?????????? - ?????-?????? ???-????-???
???????? ???????????? - ???????? ?????- ?
??????????? ?????????????? ????????,
??????????????? ??????????? ???????????? ????????
???????? ??????? ?????????? ?????? ??????
?????????? ???? ???????, ????????? ????? ???????.
??????? ? ?????????? ?? ??????? ? ????? ??
????????? ? ?????? ???????. ??-?????-???????????
?? ???????? ?????????? ????????? ????????? ??
????? ??? ?????????? ???????? E 0.1-1 ??,
??????? t h/E 10-14-10-15 ? ????????
???????????! ??????????? NSE-?????? ??????????
?????????? 10-13-10-7 ? ! ????????,
????????????? - ???????? ?????? ?????? ??????????
?????? !
8
??????????? ? ??????? ???????????? 1. ????? ?
?????? ?????????? ???????? ????????? (?60, ?70 ?
?????? ??????? ???????, ?????????),
???????????????????? (???), ?????????? ?????????,
?????????? 2. ???????????? ????????? ?
??????????? ????????????? ??? ????????,
?????????? ???????????, ?????????? ?????????,
????????? ? ?????????????? ???????????,
??????????????? 3. ???????? ??????? ???????????,
?????? ????????????? (?????????????? ????- ?
?????????????? ? ????????????? ????????,
????????), ???????? (?????????????????,
????????????????) 4. ???????????? ??????
?????????? (???), ???????? ? ???????, ??????????
???????????????? 5. ?????????? ? ????????????
?????????? ???????? ? ??????? (SANS, NSE, ???????
??????????? ?? ?????? ???????? ? ?????????
??????????????????? ?????????? ???-2)
9
??????????? ?????????? ????????? ??????????(?
????????? ???? ???????? ?? ???????? ????????????
??? ???????? ???????????? 1 ??/????? ??????? ?60)
5
40
12
23
????????? ??????????????????? ???? (???) ????????? ??????????? 58 ?? ?????????? ??????????
??????? ??????????????? ????????? ??? 23 ?? (40 ?? ???? ???????)
?????? ??????????????? ????????? 35 ??
??????????? ???????????????? ?????????
??????????? ?????????? ????????? ?60 1250 ? (??.)
??????????? ?????????? ????????? ?70 850 ? ( 125 ??3 ????????)
?????????????????? ??????? C60
????????? ????????? ???????? 1000 ? (500 ??3 ????????) (??????? ?60 99,5 )
???????????? ??????? 2400 ?
??????????????? ?????????? ?? ??? ?-????????
???????? ?????????? 2100 ? (??.) (????? ???????? 420 ??3)
??????????????????? ???? (???????????????? ??????) 21 ??
1
??? ????????? 1 ? ??????? ?60 ????????? 58 ?
?????????? ??????????
5
??????? ?? ????????? ?60
???????? ??????? ?????? ??????????
??? ????????? 1 ? ??????? ?60 ??????????
?????????????? 58 ? ????????????????? ???????.
????????? ??????? ????????? ?70 (??????? 98 ) 210 ? (??.) ????????? ??????????? ?????? ?????????? 10 ? (??.)
15
???????????? ????????????? ???????????
10
??? ????????? ????????????? ???????????? ?????? ?????????? ????????? ??? ????????? ????????????? ???????????? ?????? ?????????? ?????????
1 ?????????? ?????????? ?????????? (???????????, ??????????? ? ??.) ????????????????? ???????
2 ??????????? ?????????? ?? ???????? ??????? ????????? ?60 ?? ??????????? ????????? ?70
3 ??????????? ?????????? ?? ??????? ??????????? ????????? ?70 ?? ???????? ??
4 ?????????? ?????????? ????????? ?????????????????? ??????????? ??
5 ?????????? ?????????? ?????????? ??????????? ?? ?? ????????? ????? ?????????????? ?????????? ?76, ?78, ?84 ? ??.
6 ?????????? ?????????? (????????????? ? ???????? ?????????????? ????????????) ????????? ???????????? ?????????? ?60 (gt 99,9 ) ? ?70 (gt 99,7)
7 ?????????? ?????????? ?????????? ?????????? ?? ???????????? ?????????
8 ?????????? ??????-?????????? ?????????? ????????? ??????????????? ??????????? ??????????
9 ????? ????? ??????????? ??????????? ? ???????????? ??????????? ??????????? ???? ? ??????? ??????????????? ?????????
10 ??????????? ???????????? ??????????? ??? ???????????????? ???????? ? ??????? ??????????.
????????? ??????????? ? ????????? ????????? ????? ???????????? ??????? ?60 (? ?????????? 1 ?? /?????)
1. ?????????????? ?????????. ????????? ???? - 300 ?/??2, ??????????? ???????? ????????? ??????? 75 ?/?, ????????? ?????????? ?????????? 58 ??, ????????? ????? ????????? ?????????? ????? 770 ??????? ?????, ????? ??? 40 ?? ???? ??????????? ???????, ?????????? ?????????? ? ???? 10 ???. ????????? ??? ??????? ??? ?????????????? ??????????.
2. ??????????????? ??????????????????? ????. ????????? ??????????????????? 1,5 3 ?? ???? ?? ???? ???????????????. ???????????? ????? ?????????????? 15 ??????? ?????. ??????? ??????????????? 95 ??? ??????????? ???????? ???? ?-???????? ? ???????????? ?/? 10.
3. ??????????? ???????????????? ?????????. ????????? ?? ????????? 1-2 ?? ????????? ?? ????. ???????????? ????? ?????????? 1-2 ??????? ???. ????? ??????????? 60 ?? ???? ????????????? ?????????. ???????? ?????????? ?60 ? ??????????? 952 .
4. ?????????????????? ??????? ??????????? ????????? ?60. ?????????????????? ????????? ??????????????????? ?? 1,5 ?? ?? ??????????? ????????? ?60. ????? ?60 (???????? ?? ???? 99,5 ) - 80 ?? ???? ???????????? ???????????.
11
????????? ? ???????????? ??????
?????????? ??????????? ??????????
??????-?????????? ???????????? ??????? ?.?.,
?????? ?.?, ????? ?.?., ????? ?.?., ?????? ?.?.,
????????? ?.?.
????-?????? ??????????? ?????? ?????????
????????????????? ????????? ? ?????? ??????????,
??????????? ? ????
Grushko Yu.S., Kozlov V.S., Sedov V.P., Kolesnik
S.G., Lebedev V.T., Shilin V.A., Khodorkovsky
M.A., Artamonova T.O., Shakhmin A.L., Shamanin
V.V., Melenevskaya E. Yu., Konnikov S.G.,
Zamorianskaya M.V., Tsyrlina E.V., Krzhivitsky
P.I. // Fullerenes, Nanotubes and Carbon
Nanostructures. 2010. V.18. N 4. P. 417-421.
12
?????????? ????????? ???
??????????????? ???? ?????????????, ?????????,
??????????? ???????? ??????? ??? ?????????????
????, ??????? ??????? ??????????? ??? ?????????
? ???????? ???? ??? ??? ??????????????
????????? ???????????? ??? ??????? ????????
46Sc, 140La, 141Nd, 153Sm 152Eu, 154Eu, 153Sm,
160Tb, 169Yb, 170Tm (??????? I ? III), 177Lu.
??????? ??????? 153Sm_at_C82S46c3N_at_C80 141Nd_at_C2n,
? ?. ?. ????? ????? ???????????????????
?????????? ????????????? ? ????????? ??????? ???
????????? ?????????? ??? ??????? ? ?????.
????????? ??????? ??????????? ? ???????
152Sm_at_C2n (n, ?)153Sm_at_C2n ( 80) ?????? ???
????? ????????? ??????? ??????????????
???????? ???????? ?????????? ????????,
???????? ?? ???????? ??????????????? ???????
?????????????????? ??????? ?? ?????? Gd_at_C2n -
??? ?????????? ??????????? ??????????
Lebedev V.T., Grushko Yu.S., Orlova D.N., Kozlov
V.S., Sedov V.P., Kolesnik S.G., Shamanin V.V,
Melenevskaya E. Yu., Aggregation in hydroxylated
endohedral fullerene solutions Fullerenes,
Nanotubes and Carbon Nanostructures. 2010. V.18.
N 4. P. 422-426.
13
?????????????? ????????? ? ????????? ? ????????
???????? ?60, ????????? ? ??????????? ??????
??????????? (PS), ????-2-????????????? (P2VP) -
????????????? ??? ?????????? ??????!
?????????????? ??????? ????? (???????? ????
Yellow Submarine, RISSPO, Budapest) (?)
???????? ?????????? - ??? ?????????? ???? (RCA ),
- ????? ????????? (RN) ? ????????????
???????????????? ?????? (RD) ? 6-???????
PS-?????? (?????? ??????? RS) (b) ???????????
???????? ?????????? ????? ?????? ? 12- ?
22-??????? ??????.
?????? ?????, ?????????? ?60 ????????, ???????
????????? (?????, ??????) (??? ???,
?????-?????????)
Lebedev V.T., Vinogradova L.V., Török Gy. Neutron
scattering studies of structure and self-assembly
of star-shaped polymers with fullerene centres in
solutions // Macromolecular Symposia. Wiley-VCH
Verlag GmbHCo KGaA ("Wiley-VCH") 2010. P. (in
press)
14
???????? ?????????????? ?????????
Na2PdCl4
(??)7(?2??)7
????? (SMART) ?????? ???????
??????????
????????? ??????????? ?????????? (????????)
?????? ????????-???????? ??????? ????-??????
??????? (??)6(?????)6
15
Magnetic fluids in medicine
  • Targeted drug delivery
  • MHT (magnetic hyperthermia) in treating tumours
  • Magnetic photosensitizers for PDT (photodynamic
    therapy)

16
Photodithazine
  • Chlorine e6 derivative.
  • The most effective Russian sensitizer for PDT (l
    662 nm). http//fotoditazin.ru/, OOO
    Veta-grand.
  • The task was to increase the contrast between
    tumour and normal cells by preparation
    localization on magnetic fluid particles and
    guiding them by external magnetic field.
  • Copolymer pluronic F-127 was used to increase
    photodithazine efficiency and biocompatibility.
  • n 60, m 200.

17
???????? ? ????????? ?? ????????????????? ?????
18
??????????????? ???????? ? ??????????? Self-assem
bly, dynamics (in confinement) ?????????
??????????????? ????????????? ?????? ? ?????????
?????????? (??????????) ???????? (????????, ????,
??????????? ?????????? ?????, ??????????)
?????????????? ????????? ???????? ????????? ?
??????? (????????????, ????????????,
???????????? ???????????? ????????? ????????,
???????-????????) ???? ??????????????
????????? ??? ?????????? ???????! ????????
?????????? ???????????? ????????? ? ???.-???.
??????? ? ????????????? ????????, ?????????
?????????? ??????????? ???????????? ?????????
(?????, ??????? ????????), ?????? ?????????
????????, ???????? ?? ???????????, ??????????????
???????????? ?????? - ?????????????, ?????????
?????????? ? ?????????????? ??????, ??????????
????? ? ??????, ??????? ?????????? ? ????????
???????????? ? ??????????? ????????
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