Table 15-1, p. 612

1
Table 15-1, p. 612
2
Common Names of Carboxylic Acids
Table 15.1
3
Common Names of Dicarboxylic Acids
Table 15.1
4
p. 614
5
p. 615
6
Fig. 15-1, p. 616
7
p. 616
8
Table 15-2, p. 615
9
p. 618
10
p. 618
11
(No Transcript)
12
Electrophilic Aromatic Substitution
Fig. 9-16, p. 338
13
pKas of Substituted Benzoic Acids
Lower pKa
Higher pKa
Fig. 9-16, p. 338
14
Preparation of Carboxylic Acids Review

• Oxidation of 1? alcohols
• a.
• b.

p. 620
15
a
Preparation of Carboxylic Acids Review

• Oxidation of 1? alcohols
• a. CrO3, H2SO4
• b. K2Cr2O7, H3O

1. Oxidation of 1? alcohols

p. 620
16
Preparation of Carboxylic Acids Review
2. Oxidation of aldehydes a. b.
p. 620
17
Preparation of Carboxylic Acids Review
2. Oxidation of aldehydes a. CrO3, H2SO4 b.
K2Cr2O7, H3O
p. 620
18
Preparation of Carboxylic Acids Review
3. Oxidative cleavage a. of aryl benzenes (sect
9.10) b. carbon-carbon double bonds
i. ii.
p. 620
19
Preparation of Carboxylic Acids Review
3. Oxidative cleavage a. of aryl benzenes (sect
9.10) KMnO4 b. carbon-carbon double
bonds i. ii.
p. 620
20
Preparation of Carboxylic Acids Review
3. Oxidative cleavage a. of aryl benzenes (sect
9.10) KMnO4 b. carbon-carbon double
bonds i. (sect 8.8) KMnO4 ii.
p. 620
21
Preparation of Carboxylic Acids Review
3. Oxidative cleavage a. of aryl benzenes (sect
9.10) KMnO4 b. carbon-carbon double
bonds i. (sect 8.8) KMnO4 ii. O3,
H2O2
p. 620
22
Preparation of Carboxylic Acids Review
3. Oxidative cleavage a. of aryl benzenes (sect
9.10) KMnO4 b. carbon-carbon double
bonds i. (sect 8.8) KMnO4 ii. O3,
H2O2
p. 620
23
Preparation of Carboxylic Acids

• Oxidative Cleavage
• a. O3, H2O2

2. Reduction of Carbon Dioxide a. Examples b.
Mechanism c. Limitations
p. 620
24
Preparation of Carboxylic Acids

• 3. Hydrolysis of Nitriles
• Examples
• Limitations
• Mechanisms
• Acid catalyzed
• Base catalyzed

p. 620
25
Preparation of Nitriles

• From Alkyl Halides
• 2. From Amides

p. 620
26
Reactions of Nitriles with Reducing Agents

• Lithium Aluminum Hydride
• 2. Grignard Reagents

p. 620
27
Fig. 15-4, p. 627
28
p. 628
29
Fig. 15-5, p. 628
30
End