Blood glucose level (mM/l)

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3
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4
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Blood glucose level (mM/l)
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ICS C3H gt C57BL gt 129 gt BALB
MRC-HAR C57BL gt BALB gt C3H gt 129
GSF C3H gt 129 gt BALB gt C57BL
????????SOP???
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?????????????????????? ???? EUMORPHIA ??????
(2002-2006)?????????
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6
EMPReSS (European Mouse Phenotyping Resource for
Standardised Screens) European Mouse Disease
Clinic(EUMODIC)????SOP??????????
150?????????SOP???
http//empress.har.mrc.ac.uk/
Brown S.D.M and the Eumorphia Consortium (2005)
EMPRESS standardised phenotype screens for
functional annotation of the mouse genome.
Nature Genetics, 37, 1155. Green, E.C.J. et al.
(2005) EMPReSS European Mouse Phenotyping
Resource for Standardized Screens. Bioinformatics
21, 2930-2931. Ann-Marie Mallon et al. (2008)
EuroPhenome and EMPReSS online mouse phenotyping
resource. Nucleic Acids Research, 36, Database
issue, D715D718
7
??????????????SOP???????
??????????27???????SOP???
http//www.brc.riken.jp/lab/bpmp/SOPs/
Wakana, S. et al. (2009) Introduction to the
Japan Mouse Clinic at the RIKEN BioResource
Center. Exp Anim., 58, 443-50.
8
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11
SDOP(Standardized Description of Operating
Procedure) SOP????????(??)????
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SOP???????
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SDOP?????????(SOP)????
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SOP???????
13
SDOP??????????????/????? SOP?????(????????????)
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Lab.
Lab.
SDOP???????????????????????SOP???
Lab.
Lab.
Lab.
Lab.
14
SDOP???1 SOP???????????????
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15
SDOP???2 SOP??????????????????????????
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16
SDOP??????????
17
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18
SDOP-DB ?????????????????????????? ? (Tanaka et
al., Bioinformatics, 26(8),1333-1334, 2010)
SDOP-DB?TOP???
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(OGTT) ???????? (DEXA)??? ???? ????
SDOP-DB ??????/????????????????????????????? !!
SDOP-DB (http//www.brc.riken.go.jp/lab/bpmp/SDOP/
)
19
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20
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21
SDOP???? ?????

1. ?????????/???SOP???????????????????????

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SDOP-DB
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1. SOP????????????????????????

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