STDs Herpes genitalis

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STDsHerpes
genitalis

Syphilis

• Dominik Kralj
• Mentor A. Žmegac Horvat

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Herpes genitalis - ethiology

• HSV-2 virus, herpesviridae family
• neurotropic, neuroinvasive DNA virus

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Primary infection

• acquired through sexual contact
• presents itself with clusters of genital sores
  consisting of inflamed papules and vesicles

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Accompanying symptoms

• pain
• itching
• burning
• discharge
• fever
• headache

• myalgia
• lymphadenitis
• malaise
• dysuria
• cervicitis
• proctitis

• reccuring infections often manifest
• themselves less severely

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Latency
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Treatment

• 5 x 200mg for 5 days

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Syphilis

• caused by spirochetal bacterium Treponema
  pallidum
• known throughout history under different names
  (French disease, great pox, lues, Cupids
  disease)
• today less prevalent but still poses a problem,
  especially in underdeveloped countries
• has three stages

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Primary syphilis

• usually through direct sexual contact
• appearance of a chancre at the point of exposure
  after three weeks
• a painless, firm skin ulceration which heals on
  its own after 4 to 6 weeks
• sometimes accompanied by lymphadenopathy

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Secondary syphilis

• 1 to 6 months after primary infection

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Tertiary syphilis

• appears following a 1atency period which lasts 1
  to 10 years
• characterized by formation of gummas
  (inflammatory granulomas)
• other severe manifestations include
  cardiovascular syphilis, neurosyphilis,
  neuropathic joint disease

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Diagnostics

• Treponemal
• -TPHA
• -FTA-ABS

• Nontreponemal
• -VDRL
• -RPR

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Therapy

• Penicilin G 2.4 million IU (intramuscular)

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Thank you for your attention!