Title: Human Chorionic Gonadotropin (hCG):
1???????????
- Human Chorionic Gonadotropin (hCG)
- The Story Of Pregnancy Hormone
???
2General introduction
- ?????????
- Human Chorionic Gonadotropin (hCG)
- MeSH
- Chorionic Gonadotropin
- Placental Hormones
- Pregnancy Proteins
3General introduction
- hCG????????????,????????????????hCG??????,????????
????,????????,?????????hCG - ???hCG???????????????,???????????hCG???????????
4General introduction
- ??LH????,????, ???????,??????
- hCG???????????????(steroidogenesis),??????????????
(testosterone) - ?hCG???????6?,?hCG?12-14????
- ?????48-72 h,?????????,?????? 96 h???8 - 10
w??,???????????
5General introduction
- ?FSH?LH?TSH??,??a?ß????????a?????????????????,????
?????,??????ß??? - ?????ß-HCG,?????????
6Key things about hCG levels (1)
- ?hCG??????????? ?????hCG?????????????
- ??????hCG??(5 - 6 ???? )????
7Key things about hCG levels (2)
- ???? ???????(beta hCG)??
- The hCG hormone is measured in milli-international
units per milliliter (mIU/ml) - ?????lt 5mIU/ml ??
- gt 25mIU/ml ??????
8Key things about hCG levels (3)
- ??????? 1,000 - 2,000mIU/ml
- ??????????????,???hCG??????,???????????????????
- ???????,?????????????????
9Guideline to hCG levels during pregnancy
- 3 weeks LMP 5 - 50 mIU/ml
- 4 weeks LMP 5 - 426 mIU/ml
- 5 weeks LMP 18 - 7,340 mIU/ml
- 6 weeks LMP 1,080 - 56,500 mIU/ml
- 7 - 8 weeks LMP 7, 650 - 229,000 mIU/ml
- 9 - 12 weeks LMP 25,700 - 288,000 mIU/ml
- 13 - 16 weeks LMP 13,300 - 254,000 mIU/ml
- 17 - 24 weeks LMP 4,060 - 165,400 mIU/ml
- 25 - 40 weeks LMP 3,640 - 117,000 mIU/ml
- Non-pregnant females lt5.0 mIU/ml
10False positive of hCG?
- ?ß-HCG????????????????,?????????,?????
- - ??????????????????hCG??,????????????
- - ???????????????????,????????hCG
- - ??????????,?????????hCG???
11What can a low hCG level mean?
- A low hCG level can indicate
- -????
- -????(????)
- -????
- rechecked within 48-72 hours to see how the level
is changing.
12What can a high hCG level mean?
- A high hCG level can indicate
- -????
- -???
- -????
- rechecked within 48-72 hours to evaluate changes
in the level.
13Should hCG level be checked routinely?
- ???????????,????
- ????
- - ????
- - ??(??)
- - ???
14hCG levels after a pregnancy loss?
- ?????????4 - 6 weeks??(lt5.0 mIU/ml)
- ????,??????? (????, ??????, ????,2 weeks)
,?????? - ?????? lt5.0 mIU/ml
15?????HCG???(mIU/ml) ?????HCG???(mIU/ml) ?????HCG???(mIU/ml)
????? 12 34 56 78
5 70 66 12.5 19.5
??? 950 260 49 41
95 5750 2450 330 140
16?????HCG??? (mIU/ml) ?????HCG??? (mIU/ml) ?????HCG??? (mIU/ml)
????? 15 610 1115 1620
5 lt12.5 lt12.5 lt12.5 lt12.5
??? 15000 230 92.5 57.5
95 46500 3250 490 205
17Applications
- Prengnancy diagnosis
- Ectopic pregnancy
- Hydatidiform mole
- GTN
- PSTT
- Assistant reproduction
- Contraception
18Others
- ?????4-8?,HCG??2-3d?????
- LMP?7?,???????????????,HCG?20000mU/ml?
- ?9-10???????,??????lt5ng/ml??????(?????????),gt25ng
/ml?????????
19Others
???????????????? ???????????????? ???????????????? ????????????????
?? ng/ml ng/L
7 24.5 76.4
8 28.6 89.2
912 38 118.6
1316 45.5 142
1720 63.3 197.5
2124 110.9 346
2534 165.3 514.8
gt35 202 630
20Others
- ?8-13?????????,?????????????????(cm)6.5
- ??????2cm?????????,?????5mm????????
21The End
- THANKS FOR YOUR ATTENTION!