Nociceptive sensation. Somatic sensory analyzer

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Nociceptive sensation. Somatic sensory analyzer
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• Also different changes in human organism followed
  by pain are observed increase of muscle tone,
  accelerated heartbeat, increase of blood
  pressure, intensification of sweating, dilatation
  of pupils and elevation of glucose and cuprum
  level in plasma, activation of hemostasis.
• It considered to cause the majority of both
  visceral and biochemical reactions by excitation
  of sympathetic nervous system, which is presented
  by neurons of hypothalamus, hypophisis and cells
  in medullar substance of adrenal glands.

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• Afferent nociceptive impulses are collected into
  central nervous system by two kinds of nervous
  fibers quick a-delta myelinated nerve fibers and
  C-fibers without myelin.
• The ascending fibers are included in
  spinothalamic tract, which passes through the
  spinal cord and reach medulla oblongata. Here
  there are second order sensory neurons of
  spinomesencephalic tract.
• Fibers of spinothalamic tract synapse with
  third-order neurons in the thalamus, which in
  turn project to the postcentral gyrus of the
  contralateral cerebral hemisphere.

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Location of pathway terminations

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