Biotechnology Development: Opportunities and Challenges

1
Biotechnology Development Opportunities and
Challenges

• Dr Prakash Ghimire, Ph D
• Associate Professor Microbiology
• Tribhuvan University
• Microbiologist, WHO-IPD/NPHL/EDCD-MoH

2
Ecological Zones and Development Regions of Nepal
Far-Western Region
Mid-Western Region
Western Region
Central Region
Eastern Region
Mountains (16 districts) Hills (39
districts) Terai (20 districts)
3
Biotechnology

• Animal
• Hybrids
• Pharmaceutical
• Diagnostic
• Therapeutic
• Vaccines
• Plant
• Agriculture - NARC
• Food

4
Biotechnology

• Post Human genome situation
• Proteomics Genomics two closely related area
• Cell biology
• Immunology
• Antibodies
• Polyclonal
• Monoclonal
• Molecular biology
• Genomics
• Proteomics

5
RONAST
6
RONAST

• ACTIVITIES RESEARCH ACTIVITIES
• Biotechnology Programs -
• Conservation of Medicinal and Aromatic Plants
  Click Here- Molecular Diagnostic of Citrus
  greening Disease
• Molecular Characterization of Medicinal plants
   -Tea clones  -Bacillus thuringinsis
• Flora of Nepal Project Research on Organic
  Farming -Antagonistic Study of Ectomycorrhiza
  -Study of the role of Endomycorrhiza
• Natural Products Research -Bioprospecting of
  Cordyceps sinensis-Biopesticides study program
  -Analytical services

7
Nepal Health Research Council

• Supports health Research
• Mostly in health system research
• Negligible investment in Biotechnology

8
Medical Biotechnology In Nepal

• Immunology
• Vaccine Production
• Rabies Vaccine Production (Central Veterinary
  Research Laboratory), Tripureswor
• Antibody Production
• Everest Biotech
• Founded by biochemists at Oxford University,
  based in Oxfordshire, UK with a production
  laboratory established in Kathmandu.
• CDM TU- Non commercial/Academic Use
• Antibody Production, Purification..
• National Public Health Laboratory
• Health Services
• Flow cytometric assay ( FACS)

9
Medical Biotechnology

• Molecular Biology
• DNA Sequencing Proposed at National Forensic
  Laboratory, Khumaltar
• PCR
• RONAST- Plant molecular biology
• CDMTU Tropical diseases- Malaria, Leishmania
  etc.
• National Public Health Laboratory, Teku- SARS,
  Malaria, etc.
• VBDRTC, Hetauda- Malaria, Leishmania
• Mycobacterial research Laboratory, Lele-
  Tuberculosis, Leprosy
• Universal College/ RLAAB- Plant mol. Bio.
• Veterinary Research Laboratory, Tripureswor-
• Si-Gan Health Foundation, Maharajgunj
• Real Time PCR ( Proposed)
• National Public Health Laboratory, Teku
• Avian Influenza diagnostic service
• Cell Biology

10
Real-Time PCR
11
Challenges

• Machines without consumables
• Academic HMG Institutes
• Training of Human Resources
• Latest updates
• Research Culture
• Carrer prospects
• Research Funding Collaboration
• NHRC ?
• Big researches- Survey type, No Laboratory
  capacity development in Nepal
• Availability of Consumables in local market
• Mostly not available, If available, costs 3-5
  times of original cost
• Entrepreneurship
• Market

12
Hope for Future

• New University programs as per market
  requirements
• Medical technology Program
• Medical Microbiology Program
• Pharmaceutical Sciences Program
• Biotechnology Program
• Allied health Programs ( Radiology, Dentistry,
  Physiotherapy, Bio-medical Engineering, .)
• Availability of funding in post WTO scenario
• Introduction of newer Pharmaceutical companies
• Availability of trained /cost effective HRs
• Worldwide market in post WTO situation
• Coming up of new diagnostic companies
• Positive Government Policy ?

13
Formula for Success
A small truth to make our life 100 successful
A B C D E F G H I J 1 2 3
4 5 6 7 8 9 10 K L M N O
P Q R S 11 12 13 14 15 16
17 18 19 T U V W X Y
Z 20 21 22 23 24 25 26
14
None of them makes 100
15
Then what makes 100

• Is it money? No!!!

• Is it leadership? No!!!

• Every problems has a solution, so perhaps

Change our ATTITUDE
It is ATTITUDE towards life and work that makes
Our Life 100 Successful
16
ATTITUDE 120209202145
100
Dont you think so ?!?!?!?!
17
Thank You