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neonatal respiratory distress

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Title: neonatal respiratory distress


1
???????
  • neonatal respiratory distress

2
CBL???
Case Based on Learning
3
???????
  • ??????????????
  • ?????????????
  • ?????????
  • ??????

4
????????
  • ??????????
  • ??????????????
  • ??????,???????
  • ?????????? (pulmonary
  • surfactant,PS )??,???
  • ???????? ARDS ,?????

5
??????????
  • ????????????????
  • ?????????/??????
  • ??????????????
  • ????????????

6
???????
  • ??????? Meconium Aspiration Syndrome (MAS)
  • ???????? Hyaline Membrane Disease(HMD?RDS)
  • ????? Neonatal Pneumonia

7
  • CBL???

8
??????? Meconium
Aspiration Syndrome (MAS)
  • ????
  • ???????????
  • ?????????
  • ?????????
  • ????????
  • ????PaO2 ? ?PaCO2 ?????

9
???????? Hyaline
Membrane Disease(HMD?RDS)
????????????,????? ??,????????????????? ?????
,???????
10
???????
  • ???????(PS)???RDS?????
  • PS?? ?1820?????,3536?????
  • PS??
  • PS??

11
??
?? ??? ??? ???????(IDM)
?? PS?
????
V/Q ? PaO2 ?
PaCO2 ? ?? ?
??????
??????
?????
?????????
??????
?????
12
RDS???????
?? (wks) ??? ()
2830 gt70
3132 4055
3335 1015
gt36 15
????,?????
13
RDS????
?? ??

?? PS?????
?? ?????
??? ??????
???? ???? ????? ???????
???????(IDM) ????????????????
??? ???????????
14
  • ????
  • ??????
  • ???????????????
  • ??????????
  • ???

15
?????Neonatal Pneumonia
  • ????
  • ??????,??????
  • ???????????????
  • ????????
  • ????????
  • ????PaO2 ? ?PaCO2 ?

16
???????X???
17
HMD/RDS?X???
18
MAS?X???
19
??????X???
20
????????????
  • ????( Monitoring)
  • ????T?????(?)??
  • ??
  • ??(????????)
  • HR
  • PaO2 ?SaO2, ????

21

??(Oxygen therapy)
?? ?????, PaO2lt50mmHg???????(TcSO2)lt
90 ?? ??? ?? ???? ?? ??PaO25070mmHg?TcSO29095

22
????(Mechanical ventilation)
  • ?????????
  • ??
  • ?????????
  • SaO2???
  • ?????????PaO2 ? /PaCO2 ?

23
CPAP
  • ??
  • ?????????,FRC??,????????,
  • ????????????
  • ??(???????,?PaCO260mmHg?)
  • FiO2gt0.4?,PaO2lt50mmHg?TcSO2lt90(?????????)
  • ??RDS
  • ??????
  • ????
  • ?? CPAP 5cmH2O ,FiO2 0.4

24
CPAP
  • ??????
  • CPAP 12cmH2O/? ,????8cmH2O
  • FiO2 0.05/? ,????0.8
  • ????
  • PaO2 5080mmHg ?TcSO2 9097
  • PaCO2lt60mmHg
  • ????
  • FiO2gt0.4?CPAP 3cmH2O?,PaO2 gt60mmHg
  • ?TcSO2 gt92

25
????
  • ?????????
  • ??/???? A/C
  • PIP 15-25 cmH2ORR 25-35
  • I/E11.5-2.5PEEP 4 - 12 cmH2O
  • ?????? PSV 6-10 cmH2O
  • ?????? HFOV

26
????
  • ??????
  • ??? 10-20 ?u/kg/d
  • ????? 50-100mg /kg/d
  • ??? 50-100mg /kg/d
  • PS??? 80-120 mg /kg/?
  • ?(?)?? ???????

27
PS????
?? ??????,??????? ?? ????????(??24???) ??? 24
? ??PS Survanta(??) Exosurf (????) Curosurf (??)
28
??
  • ??
  • ??
  • ????

29
??
  • ???????????
  • ?????(TPN)

30
? ?
????MAS?RDS???????
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