Bioinformatics

1
Bioinformatics

• Stephen Voglewede

2
What is Bioinformatics

• Computers have changed a lot of fields
  including biology

3
Bioinformatics?

• Sequence analysis
• Evolutionary mapping
• Modeling of biological systems

4
Algorithms and Tools

• Needleman-Wunsch
• UCSC Bioinformatics Website, NCBI
• BLAST, Genome Browser

5
Current Research

• Vijay Pande Folding_at_home
• David Baker Foldit
• Still looking for UCSC candidate
• Areas of interest structural elucidation,
  information systems for drug testing

6
What is your approach

• Bioinformatics Textbook from Prof. Khuris class
  pretty useful overview
• Plenty of resources for Human Genome Project
• Pour through research papers for Needleman-Wunsch
  and for current research access issue might
  need to be addressed

7
What will be your final product?

• Report containing the following
• Brief overview of history of bioinformatics
• Description of some of the algorithms commonly
  used
• Walkthrough of some of the tools available to for
  public use
• Brief overview of some of the more interesting
  research in Bioinformatics right now