?????,???????????(systemic lupus erythematosus,??SLE),???????????????????????

1
???????? ???????
2
?????????

1. ?????,???????????(systemic lupus
   erythematosus,??SLE),???????????????????????
2. ??????????????????,??????????,???????????
3. ????,?????????????????????????
4. ?????????,?????????????????????????,??????????????
   ????????????????????????????

3
????????-1
1.????SLE???????????,???????????????SLE???????C3b
??????,???????????????,?????????? 2.???????SLE??
???,????????????????????????????????HLA?SLE???????
,????????????
4
????????-2
3.??SLE?????????,????????????????,???????????????
????????????????????????,??????????? 4.???(???)S
LE??????????,?????????????,????SLE????,???????????
?????
5
??????????-1

1. ?????(malar rash)?????????,??????,??????,????????
   
2. ??????(photosensitivity)??????,???????,??????????
   ??
3. ?????????????????????

http//119.img.pp.sohu.com/images/blog/2008/2/11/1
9/20/118a5ae6108.jpg
6
??????????-2

1. ???(arthritis)????????????,??????????,???????
2. ???(serositis)????????(??????????????),??????????
   ???????????????????

6.???? ?????????????4,000?????????
1,500??????????????????????? ????,??????????????
,?????? ???????????????
7
??????????-3

1. ????????????????????,???????????????????DNA????S
   m????????????
2. ???????????????????????????,????????????,????????
   ???????,???????????
3. ???????(ANA,antinuclear antibody)????????

??9????,????????????????,????????SLE??????????????
????????
8
???????-1
1.???????????SLE???,?????????????????????????????
???????,??????????????????????,???????????? 2.????
???????????,??????12????????????,??????,????????
?????????????????????
9
???????-2
3.??????????????????SLE???,??????????????????????
????????,??????????????? 4.????????????SLE???5,?
??????????????????????????????,????????????????
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graphics/ph5.jpg
10
???????-3
5.???????????????????????,?????SLE?????????????,?
???,????????,?????????DNA????,??????? 6.?????????
?????????????Procainamide?Isoniazid?Hydralazine??
???????????????????????,????SLE????????????,?????
????????????,????????????
11
??????????
12
1. ??????

1. ???????????????????,??????, ?????,??????????,????
   ?????? ????????,???????????,??????,
   ??,???,????,??????.
2. Endoxan?????????????,???????????,???????????????
   ?????????,?????????????????,?????????.

13
2.????

1. ????????????????????????,??????.
2. ??????????????????,??????????????????,???,???,??
   ?,????????,?????????.
3. ??????? (Plaquenil),??????,??????,
   ??????????????????????,??,????,????, ?????.
4. ????? ??? (Imuran), ???????????????
   ??????????????, ????????? ??????????Endoxan,
   cyclosporine?.

14

1. ???????????????????????.
2. ???????????????????????????,?????????????????,???
   ?????.

• 5.????????
• ?? ?????????,???????????????????????????????,
  ????.
• ??????????????,??????????????,???????,?????????.
• ???????????.

15
????????????

• ???????????????????????????????????????????(SPF)1
  5???????,????????????????
• ????????????????????
• 3.???????,???????????
• 4.???????????????????????????,???????????????????
  ????????????,?????,??????,??????????

16
http//www.hercom.org.tw/image.php?numS01945-1
17
????? ???????? ?????? ??????? ???? ???????? 
2007/06/03 ???????
???????????,???????? ,?????????????????,? ?????,??
?????????,?? ?????????????????    
???????????????,???? ????????,??????????? ?????,
?????????????????,?????????????,????,????,????????
???????,?????????????????????????,?????????????,??
??,???????????????????????,??????????,????????????
????,??????,??,??????,??????????????,?????????????
?????????,??????
http//www.ttv.com.tw/096/06/0960603/0960603449620
1I.htm
18
?????? ??????? ????? ???????
2008/03/03  ???????
????????,??????,?? ??????????????,??? ????????????
?????, ???????,?????????? ?????? ????????????,????
?? ?,??????,?????????? ???,??????????????, ??????,
???????????????????,???????????????. ??????????,??
????????????????????,????????,????????????????????
??,?????,????????????.????,????????????????,??????
?,????????????????????,???????
http//www.ttv.com.tw/097/03/0970303/0970303466550
1I.htm
19
END
???? http//119.img.pp.sohu.com/images/blog/2008/
2/11/19/20/118a5ae6108.jpg http//www.londonlupusc
entre.co.uk/chinese/images/graphics/ph5.jpg http/
/www.hercom.org.tw/image.php?numS01945-1 http//w
ww.ttv.com.tw/096/06/0960603/09606034496201I.htm