Catabolic Pathways 2nd Year Physiotherapy

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Catabolic Pathways2nd Year Physiotherapy

• By
• Eman Mokbel Alissa, Ph.D.

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Lecture (1) Contents

• Metabolism Introduction
• Thermodynamics
• Catabolism and Anabolism
• Metabolic Map
• Examples of metabolic pathways

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Lecture (2) Contents

• Bioenergetics Definition
• Biomedical Importance
• Central Reactions of Metabolism
• ATP as energy carrier
• ATP, ADP, and AMP structures
• ATP / ADP Cycle
• Types of Chemical Bonds
• Mechanism of Energy Collection
• Energy currency

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Lecture (3) Contents

• Electron Transfer Chain (ETC)
• Chemiosmotic Hypothesis
• Conservation of ?G from NADH oxidation in a pH
  gradient
• Respiratory Control

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Lecture (4) Contents

• Some Points About Glucose
• Glucose Oxidation
• Fate of Glucose
• Glycolysis ATP and NADH production
• Alternative Pathways of Pyruvate
• TCA Cycle
• Summary of ATP Produced

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Lecture (5) Contents

• Fat and Fatty Acids
• Fatty Acid Oxidation
• ß oxidation
• ATP Generation from ?-Oxidation
• ß-oxidation in peroxisome
• Unsaturated FA oxidation
• FA oxidation with odd Carbon No.
• a-oxidation

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Lecture (6) Contents

• Amino acids introduction
• N2 Metabolism
• Overall flow of nitrogen in amino acid catabolism
• Removal of Nitrogen
• Combined actions of amintoransferase and
  glutamate dehydrogenase reactions
• Ammonia transport to liver
• Urea Cycle
• Link between urea cycle and TCA cycle