Cytopathology Challenge! Weekly Cases

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Cytopathology Challenge! Weekly Cases

• October 22th 2007
• Pap Smear Special Edition!

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• 24 year old female. ThinPrep pap
• Trichomonas
• Lactobacillus
• Gonorrhea
• Bacterial Vaginosis
• Artifact

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3

• 34 year old female. ThinPrep pap
• Reactive endocervical cells
• Squamous metaplasia
• ASCUS
• LSIL
• HSIL

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4

• 34 year old female. ThinPrep pap
• Endocervical cells
• HSIL
• Endometrial cells
• Squamous metaplasia
• Lymphocytes

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5

• 29 year old female. ThinPrep pap
• Squamous metaplasia
• Reactive endocervical cells
• ASC-US
• LSIL
• HSIL

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6

• 24 year old female. ThinPrep pap
• Trichomonas
• Lactobacillus
• Gonorrhea
• Bacterial Vaginosis
• Artifact

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7

• 29 year old female. ThinPrep pap
• Squamous metaplasia
• Reactive endocervical cells
• ASC-US
• LSIL
• HSIL

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8

• 29 year old female. ThinPrep pap
• Squamous metaplasia
• Reactive endocervical cells
• ASC-US
• LSIL
• HSIL

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9

• 29 year old female. ThinPrep pap
• Reactive
• Endocervical cells
• ASC-US
• LSIL
• HSIL

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34 year old female. ThinPrep pap A. Squamous
metaplasia B. Reactive endocervical cells C.
ASC-US D. LSIL E. HSIL
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• 34 year old female. ThinPrep pap
• Contaminant from a BAL
• HSIL
• Endometrial cells
• Adenocarcinoma
• Tubal metaplasia

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Answers

• D Bacterial Vaginosis
• Clue cells with cocci on them
• D LSIL
• Koilocytes!
• C Endocervical cells
• Honeycomb, regular, not dysplastic
• E HSIL
• High NC ratio, irregular nuclei
• B Lactobacillus
• Rods on the cells
• D LSIL
• Koilocytes again!
• A Squamous Metaplasia
• Can look like HSIL, but nuclei not so big and
  still regular in contour.
• A Reactive
• See the trichomonas hiding in there
• E. HSIL
• High NC ratio, irregular nuclei
• E Tubal metaplasia