HHMI meeting, FOLDING

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PROTEIN PHYSICS LECTURE 7
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Main secondary structures
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H-bonds
Helices Right and Left
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Mirror-asymmetric amino acids
mirror-asymmetric (chiral) helices Right
?-helix
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Right ?-helix
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Right ?-helix Right 310 helix
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ALA, etc. GLY only
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???, twisted
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???, twisted
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Mirror-asymmetric amino acids
mirror-asymmetric twist of ?-sheets
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?-hairpin with turn
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turn I
turn I
turn II
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?-bulge
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collagen triple helix
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Experimental study of secondary structure X-ray
crystallography
NMR spectroscopy (cross-peaks)
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Experimental study of secondary structure
Far UV CD spectra (peptide groups)
IR spectra (amid I, CO bond)
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Membrane
Globular
Fibrous
H-bonds hydrophobics