Respiratory failure

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???? Respiratory failure
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???????(Concept Classification)
1.????(Respiratory Failure)
????????????????,??????(?)? ????????,??PaO2??8.0kP
a(lt60mmHg),??? ???PaCO2 ??6.67kPa(50mmHg)??????
Respiratory failure is a syndrome in which
the respiratory system fails in one or both of
its gas exchange functions oxygenation and
carbon dioxide elimination. In practice,
respiratory failure is defined as a PaO2 value
of less than 60 mm Hg while breathing air or a
PaCO2 of more than 50 mm Hg. (mmHgmillimeter
hydrargyrum)
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(3)???????(According to duration)
??????(Acute respiratory failur).
??????(Chronic respiratory failure).
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?????????(Hypo-motility of pulmonary
ventilation)
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????????(Disorders of chest wall)

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?????????????? ???????????,????? ??????
?????,???????????, ????????? ?
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PAO2PiO2-( PACO2/R) PAO2150mmHg
-(40mmHg/0.8)100mmHg?(PAO2PaO2) PaCO2PACO20.86
3VCO2/VA ????????, PaCO2????????????????? VCO2
????????CO2VA ????????
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2. ??????????? (Ventilation-perfusion-
mismatching) ?????????? ???????(VA,4L/min)?????(Q,
5L/min)??? (VA/ Q)??0.8?

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VA Q
VA/ Q ??? 1.2L/min 0.4L/min
3.0 ??? 1.8L/min 2.0L/min 0.9 ???
2.1L/min 3.4L/min
0.6 ?????????????? ?????PaO2?PAO2??????
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??? PCO2 45mmHg
??? PCO2 40mmHg
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?????( Injurious changes)
PaO2lt 40 mmHg,PaCO2gt 80 mmHg ?????(-)
?????CO2?? ???????????(-)
???????????????????
????? ?????
?????? ??
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5.?????? ?????????RBC??? ?????????,???????,??????
6.????? ??????? ??????(??????????)? ????????????
?? 7.??????? ???????????????????? ?????????????
???? ??DIC???????????????
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???? ????? ?????? ?????????? ???
1.????????,???????????? 2.????????paCO2????
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