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Clinical approach to xerostomia

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4- Systemic disease. Sjogren. syndrome. Renal failure. Diabete. Granulomatose. diseases. HIV infection. Malnutrition. Late stage liver disease. GVHD. Primary . Biliary – PowerPoint PPT presentation

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Title: Clinical approach to xerostomia


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Clinical approach to xerostomia
  • Dr. Abbas Javadzadeh
  • Dr. Atessa Pakfetrat
  • Associate Professor of
  • Oral medicine Department
  • Mashhad Dental School

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Xerestomia is a symptom not a diagnosis or
disease
?
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Clinical evaluation of xerostomia
  • Subjective or objective
  • signs and symptom

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Clinical evaluation of xerostomia
  • 2. Permanent or temporary?
  • Acute or chronic?
  • Clinical course?

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Clinical evaluation of xerostomia
  • 3. Symptoms of salivary gland dysfunction

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  • 4. Associated diseases

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Clinical evaluation of xerostomia
  • 5. History
  • Review of system
  • PMH, PDH

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Etiology
  • 1-Iatrogenic
  • Drugs
  • Radiation
  • chemotherapy
  • 2- Developmental
  • Salivary gland agenesis

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3- Water/metabolite loss
  • Impaired fluid intake
  • Hemorrhage
  • Vomiting/diarrhea

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4- Systemic disease
  • Sjogren syndrome
  • Renal failure
  • Diabete
  • Granulomatose diseases
  • HIV infection
  • Malnutrition
  • Late stage liver disease
  • GVHD
  • Primary Biliary cirrhosis
  • Chronic Active Hepatitis
  • Vasculitis, ..

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  • 5- Psychological Factors Affective
    disorders
  • 6- Local factors
  • Decreased mastication Smoking Mouth
    breathing
  • 7- Rarities
  • Amyloidosis Bells palsy Cystic
    fibrosis hemochromatosis

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Imaging
Serologic tests
  • Para clinic

..
Sialometry
Biopsy
Salivary gland function test
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Systemic stimulation
Symptomatic
  • Treatment

Non-Drug Stimulation
Drug substitution
Treatment of associated diseases
Psychological Treatment and consult
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