Lab 35A

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Lab 35A

• Lymphoid Tissues

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Slides

• Peyers Patches Label the lumen of the digestive
  tract, digestive tissue, and lymphoid tissue.
• Lymph Node Label capsule, subcapsular space,
  nodules within the lymph node, germinal centers,
  the hilus region, and any visible blood vessels.
  Using a higher power objective, examine (look at,
  but dont draw) a germinal center.

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Nodules
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Lymph Node - Structure

• Trabeculae fibrous partitions made of collagen
  fibers that extend from capsule into interior of
  lymph node
• Hilus shallow indentation where blood vessels
  and nerves reach the lymph node
• Afferent Lymphatic Vessels carry lymph from
  peripheral tissues to lymph node
• Efferent Lymphatic Vessels leave lymph node at
  hilus, carry lymph to venous circulation

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Lymph Flow

• Flows from afferent lymphatics through lymph node
  in a network of sinuses
• From subcapsular sinus
• contains macrophages and dendritic cells
• Through outer cortex
• contains B cells within germinal centers
• Through deep cortex
• dominated by T cells
• Through the core (medulla)
• contains B cells and plasma cells
• organized into medullary cords
• Into hilus and efferent lymphatics

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Lymph Node
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Slides

• Spleen Draw and clearly label splenic nodules,
  white pulp, and red pulp. Can you find a central
  artery?
• Thymus Use low power, label septa, medulla,
  cortex, and any blood vessels.
• Which region of the thymus is primarily composed
  of epithelial cells? What hormone do these
  epithelial cells make and release? What is
  believed to be the function of this hormone?

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Spleen
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Thymus