Drill: Draw: ortho, meta,

1
Drill Drawortho, meta, para-hydroxybenzoic
acid
2
Amines
3
Amines

• Organic derivatives of ammonia

4
Ammonia

• H
• H-N
• H

5
Ammonium

• H
• H-N-H
• H

1
6
Primary Amine

• R1
• H-N
• H

7
Secondary Amine

• R1
• R2-N
• H

8
Tertiary Amine

• R1
• R2-N
• R3

9
Quaternary Amine

• R1
• R2-N-R4
• R3

1
10
Naming Amines
11
Alkyl amine

• R1
• H-N
• H

12
Methylamine

• CH3
• H-N
• H

13
Methylethylamine

• CH3
• CH3-CH2-N
• H

14
Trimethylamine

• CH3
• CH3-N
• CH3

15
Tetramethylammonium

• CH3 1
• CH3-N-CH3
• CH3

16
Trimethylammonium

• CH3 1
• CH3-N-H
• CH3

17
Common Amines
18
Phenylamine or Aminobenzene
NH2
Aniline
19
N-Methylaniline
H
N-CH3
20
Diphenylamine
H N
21
Para-aminomethylbenzenepara-aminotoluenepara-met
hylanilinepara-toluidine
CH3
H2N
22
Para-aminobenzoic acid
O
NH2
C
HO
23
1,4-butyldiaminePutrescine

• H2N CH2 CH2
• CH2 CH2 NH2

24
1,5-pentyldiamineCadaverine

• H2N-(CH2)5-NH2

25
Organic HW

• Draw name 5 isomers of
• C4H11N

26
Draw N-Cyanoformamide
27
Drill Draw

• ortho-toluidene
• N-phenylanaline
• ethylammonium

28
Heterocyclic Amines
29
Pyrrolidine
H N
30
Pyrrole
H N
31
Piperidine
N-H
32
Pyridine
N
33
Indole
N
H
34
Purine
N
N
N H
N
35
Pyrimidine
N
N
36
Amino Acids
37
Common Amino Acid

• H
• R-C-COOH
• NH2

38
Glycine

• H
• H-C-COOH
• NH2

39
Alanine

• H
• H3C-C-COOH
• NH2

40
Phenylalanine

• H
• -CH2-C-COOH
• NH2

41
Drill Draw the Following

• 2-amino-N-cyclohexyl-N-phenyl-propanoic acid

42
MakingAmines
43
Making Amines

• H3N X-R R-NH3 X-
• ammonia alkyl halide --gt alkylammonium
• R-NH3 X- MOH
• R-NH2 MX HOH

44
Net Results
H3N X-R MOH ammonia alkyl halide
base--gt R-NH2 MX HOH alkyl amine salt
water
45
Making Amines
NH3 I-CH2-CH2-CH3 KOH ammonia
propyliodide potassium hydroxide
46
Products
H2N-CH2-CH2-CH3 KI H2O propyl amine
potassium iodide water
47
Predict Products

• Phenyl iodide
• ammonia
• potassium hydroxide

48
Polysubstituted Amines
base

• H3N X-R R-NH2
• R2
• H2NR X-R R-NH
• R2
• HNR2 X-R R-N-R3

base
base