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actin

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... your teaching. * actin actin troponin actin troponin tropomyosin actin troponin tropomyosin actin troponin tropomyosin myosin binding ... cock the heads Ca2 ... – PowerPoint PPT presentation

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Title: actin


1
(No Transcript)
2
actin
3
troponin
actin
4
tropomyosin
troponin
actin
5
tropomyosin
troponin
actin
6
myosin binding site
tropomyosin
troponin
actin
7
(No Transcript)
8
Ca2
Ca2
Ca2
Ca2
9
Ca2
Ca2
Ca2
Ca2
Calcium ions are released from the sarcolemma
after stimulation from the T system
10
Ca2
Ca2
Ca2
Ca2
11
Ca2
Ca2
Ca2
Ca2
the calcium ions bind to the troponin and changes
its shape
12
Ca2
Ca2
Ca2
Ca2
the calcium ions bind to the troponin and changes
its shape
13
Ca2
Ca2
Ca2
Ca2
14
Ca2
Ca2
Ca2
Ca2
15
Ca2
Ca2
Ca2
Ca2
the troponin displaces the tropomyosin and
exposes the myosin binding sites
16
Ca2
Ca2
Ca2
Ca2
17
Ca2
Ca2
Ca2
Ca2
18
Ca2
Ca2
Ca2
Ca2
the bulbous heads of the myosin attach to the
binding sites on the actin filaments
19
Ca2
Ca2
Ca2
Ca2
20
Ca2
Ca2
Ca2
Ca2
21
Ca2
Ca2
Ca2
Ca2
the myosin heads change position to achieve a
lower energy state and slide the actin filaments
past the stationary myosin
22
Ca2
Ca2
Ca2
Ca2
23
Ca2
Ca2
Ca2
Ca2
24
Ca2
Ca2
Ca2
Ca2
ATP binds to the bulbous heads and causes it to
become detached
25
Ca2
Ca2
Ca2
Ca2
ATP binds to the bulbous heads and causes it to
become detached
26
Pi
A
Pi
Pi
Pi
Pi
A
Pi
Pi
A
Pi
Pi
Ca2
Ca2
Ca2
Ca2
hydrolysis of ATP provides the energy to
re-cock the heads
27
Pi
A
Pi
Pi
Pi
Pi
A
Pi
Pi
A
Pi
Pi
Ca2
Ca2
Ca2
Ca2
hydrolysis of ATP provides the energy to
re-cock the heads
28
Pi
A
Pi
Pi
Pi
Pi
A
Pi
Pi
A
Pi
Pi
Ca2
Ca2
Ca2
Ca2
29
Pi
A
Pi
Pi
Pi
Pi
A
Pi
Pi
A
Pi
Pi
Ca2
Ca2
Ca2
Ca2
calcium ions are re-absorbed back into the T
system
30
Pi
A
Pi
Pi
Pi
Pi
A
Pi
Pi
A
Pi
Pi
Ca2
calcium ions are re-absorbed back into the T
system
31
Pi
A
Pi
Pi
Pi
Pi
A
Pi
Pi
A
Pi
Pi
Ca2
the troponin reverts to its normal shape and the
tropomyosin move back to block the myosin binding
sites
32
Pi
A
Pi
Pi
Pi
Pi
A
Pi
Pi
A
Pi
Pi
Ca2
the troponin reverts to its normal shape and the
tropomyosin move back to block the myosin binding
sites
33
Pi
A
Pi
Pi
Pi
Pi
A
Pi
Pi
A
Pi
Pi
Ca2
the troponin reverts to its normal shape and the
tropomyosin move back to block the myosin binding
sites
34
Pi
A
Pi
Pi
Pi
Pi
A
Pi
Pi
A
Pi
Pi
Ca2
phosphocreatine regenerates ATP
35
A
Pi
Pi
Pi
Pi
A
Pi
Pi
Pi
A
Pi
Pi
Ca2
phosphocreatine regenerates ATP
36
A
Pi
Pi
Pi
A
Pi
Pi
Pi
A
Pi
Pi
Pi
Ca2
phosphocreatine regenerates ATP
37
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