Title: Motor function of gastrointestinal tract
1Motor function of gastrointestinal tract
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3Phases of swallowing act of digestive lump
- There are 3 phases of swallowing oral,
pharyngeal, esophageal. Oral phase food passes
from the mouth into the pharynx through
oropharyngeal isthmus. It is voluntary as well as
reflex. This is initiated when the bolus reaches
a depression in the middle of the tongue. The
stimulation of the receptors already described
starts the swallowing reflex. Mastication and
respiration are stop. The pharyngeal phase food
is pushed from the pharynx into the esophagus.
Stage 1 and 2 are completed normally in 1 second.
The esophageal stage food reaching the upper
end of the esophagus is passed into the stomach.
It takes about 10 seconds. The 2 and 3 stages are
pure reflex actions. Swallowing can be done as
voluntary act, but mostly it is a reflex action.
4Regulation of swallowing act
- From the receptors of mucous membrane covering
oral cavity afferent impulses arise and travel
via the fifth, ninth and tenth cranial nerves
through their various branches. Stimulation of
the superior laryngeal nerve alone can produce
reflex swallowing. Swallowing center is a group
of neurons present in the reticular formation of
the medulla oblongata. It influenced by the
pre-central gyrus, amygdala, inferior frontal
gyrus and inferior colliculus also. - Efferent nerves There are chiefly the
hypoglossal (concerned with 1 stage)
glossopharyngeal (with 2 stage) and vagus (with 2
and 3 stages) nerves. The 5, 7 and 11 cranial
nerves also have some role in this process.
5Peculiarities swallowing of liquid
- Concentration of tongue root muscles, bottom of
oral cavity and soft palatinum help to fluid
swallowing. Fluid enters to esophagus and after
that go to the down part by help of gravity
force. - Speed of fluid passing of esophagus is more
quickly than peristalsis of esophagus. These
process need from 1 to 2 seconds. Fluid stop for
a few part of second in the down part of
esophagus to the time of peristalsis wave come.
At these time they enter to stomach.
6Role of motor function of stomach in digestive
processes
- The motor function of the stomach is effect by
contraction of the smooth muscle fibers forming
its wall. Its purpose is to mix the stomach
contents and to force food out of the stomach
into the intestine. An important role in
regulation that passage of food is played by the
sphincters.
7Types of peristaltic waves
- Two types of relatively short and recurring
contractions of the muscles are distinguished.
The first is encountered after a meal, when acid
gastric juice is secreted. It is in fundal and
caudal part of stomach. There are 3 types of
waves in fundal part of stomach (peristaltic
waves with low amplitude tonic-peristaltic
with higher duration and amplitude tonic which
do not pass). Also there are 3 types of waves in
caudal part of stomach (with low amplitude
higher amplitude and duration series of big
rythmic contraction on the phone of tonic
contraction). The second type of contraction
appears when food passes from the stomach into
the intestine, i.e. during the so-called
evacuation of the stomach, and also during the
hunger contractions of an empty stomach. There
are 3 types of waves short period of strong
contraction during more than 10 minutes which is
change by prolong period of rest (more than one
hour) middle intensive contractions which are
present all time lower contractions which are
present all time.
8Regulation of motor function
- Impulses via the vagus and sympathetic nerves are
of the greatest importance to this motor
activity. The vagus nerve mainly stimulates
contraction (force and rate), the splanchnic
nerve inhibit gastric movement. - Humoral influences and chemical stimulation of
the mucous membrane have a marked effect on
gastric movement. The humoral agents that
initiate contractions of the smooth muscles of
the stomach are gastrin, histamine, choline, and
potassium ions enterogastrone, adrenaline and
noradrenaline, and calcium ions inhibit gastric
movements. - The smooth muscles of the stomach possess
automatism. The muscular coat of the stomach
contains many nerve cells forming Auerbach's
plexus, which apparently participates in
coordination of the contractions of the various
groups of muscle fibers.
9Passage of food from stomach to duodenum
- The contractions of the gastric muscles force
food from the stomach into the duodenum. The food
that moves is the surface layer which passes
along the lesser curvature until it reaches the
pylorus, then leaves the stomach through the
opening in the sphincter. - The rate at which food passes into the duodenum
varies according to its amount, composition, and
cosistency and to the amount of gastric juice
secreted. Carbohydrates are evacuated more
rapidly than food rich in proteins and that more
rapidly than food rich in fats. Fluids pass into
the intestine almost immediately after entering
the stomach.
10Role of sphincters in evacuation of food from
stomach to duodenum
- The mechanism of gastric evacuation used to be
attributed to the fact that the pyloric
sphincter, open in an empty stomach, periodically
closes and opens during digestion. Its opening is
caused by stimulation of the mucous membrane at
the exit from the stomach by the HCl of gastric
juice. Some food then passes into the duodenum,
and turns its contents from the normal alkaline
state to acid. The acid acts upon the duodenal
mucosa, causing a reflex contraction of the
pyloric muscles (closure of the sphincter), so
arresting the passage of food from the stomach.
Once the acid is neutralized by excreted juices
the intestinal contents again turn alkaline and
the whole process is repeated. Since alkalinity
persists over a considerable interval, a new
portion of food leaves the stomach after the
previous one has been adequately treated. The
closing of the pyloric also occurs when fats are
introduced into the duodenum.
11Regulation of evacuations speed of food from
stomach to duodenum
- The following factors are of importance to the
passage of food into the intestine 1) the
consistency of the gastric contents (the gastric
contents enter the intestine as soon as they
acquire a fluid or semifluid consistency) 2)
their osmotic pressure (hypertonic solutions
inhibit evacuation and leave the stomach only
after they have been diluted by gastric juice to
an isotonic concentration) 3) how full the
duodenum is (distention of the duodenum also
delays evacuation and can even cause its
temporary arrest). The evacuation is controlled
by the nervous system and humoral factors.
12Meaning of motor function of small intestine in
digestion process
- By help of the movements of the small intestine
part of chyme mixed with juice of pancreas, bile
and secretes of intestinal glands.
13Characteristic of shortenings types of small
intestine
- Three types of intestinal movements are
distinguished rythmical segmentation, pendular
and peristaltic. - Rythmical segmentation is a cotraction of
circular muscles on the distance 1-1,5 cm which
are separated one from another on the distance
15-20 cm. - Pendular movement is contraction of small part of
longitudinal muscles. By help of that wall of
intestine change according to chyme. That is why
chyme transmitted back and forward and mixing. - Peristalsis movement is a circular constriction
forms above a bolus of food owing to contraction
of the circular muscles, while the lumen below
the bolus is dilated by contraction of the
longitudinal muscles. As a result, the intestinal
contents move toward the widened part then
contraction of the circular muscles spreads to
this part which in turn is constricted, while the
segment lying below it is distended by
contraction of the longitudinal musculature
14Regulation of motor function of small intestine
- Regulation of small intestines movement may be
myogenic, nervous and humoral. There are 2
pacemakers in small intestines in the entrance
place of bile and pancreatic ducts in duodenum
and in ileum. The anterior hypothalamus stimulate
motility, posterior inhibit motility. Stimulate
motility acethylcholine, inhibit
katecholamines, serotonine, histamine,
bradikinine.
15Role of motor function of big intestine in
digestion process
- In large intestine chyme concentrated by help of
absorption of water. Electrolites, water-soluble
vitamins also absorbed here. In large intestine
is formed fecus. Chyme is moving through all
digestive tract during 2-3 days. More time it
present in large intestine. 3-4 time per day
strong propulsive peristalsis wave transport
contents in caudal direction.
16Regulation of motor function of big intestine
- Plants, celulose, which are bad digested,
stimulate peristalsis. Parasympathetic nerves
stimulate, and sympathetic nerves inhibit motor
function of large intestine.
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