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Triamcinolone and Bevacizumab were intravitreally administered to patients with posterior Uveites and those with diabetic/BRVO-associated macular edema, ... – PowerPoint PPT presentation

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Title: Contributing Authors


1
Intravitreal Injection of Triamcinolone
and Bevacizumab During Cataract Sugery
Tokai eye clinic 399 Hadokoro-cho Tsu,
Japan tokaieye_at_mint.or.jp
Contributing Authors Kyoko Besho MD. Yuko Shono
MD. Yoshimasa Nakai MD.
2
Purpose
Triamcinolone and Bevacizumab were
intravitreally administered to patients with
posterior Uveites and those with
diabetic/BRVO-associated macular edema,
respectively and efficacy of the drug injection
during cataract surgery was evaluated. So the
result will be reported.
3
Material / Methods
Pars plana injection of drugs were made into the
vitreous cavity following 2mm incision,
phacoemulsification and cataract extration.
Pars plana injection
4
Triamcinolone 4mg administered Posterior
uveites 7eyes/5patients Bevacizumab 1mg
administered Diabetic macular edema
14eyes/11patients BRVO
8eyes/8patients
29eyes/24patients
Anterior chamber flare Kowa Laser Flare
Macular thickness Zeiss,Cirrus HD-OCT.
5
Result
Visual acuity (BCVA)
Before Surgery
7days After Surgery
29eyes/24patients
Mean Visual acuity,7days after cataract surgery
Improved 20/50 for 29eyes
6
Result
(log MAR)
1.4
1.2
20/250
1.0
Visual acuity (BCVA)
0.8
0.6
20/80
0.4
20/60
20/40
0.2
7days Surgery
30days surgery
Before Surgery
1day After
Uveites 7eyes/5patients
Uveites, mean visual acuity, before surgery mean
20/250, one day after surgery It improved to
20/80, 7days 20/60 and 30days 20/40.
7
Result
Laser Flare call Meter
Anterior Chamber flare
Uveites 7eyes/5patients
The mean flare in anterior chamber was 33pc/ms
before surgery, 65pc/ms 1day after surgery, but
improved to 34pc/ms 7days after, and 20pc/ms
30days after.
8
Result
Visual acuity (BCVA)
BRVO-Macular edema 8eyes/8patients
BRVO, mean visual acuity, before surgery was
20/150, but improved after 1day to 20/50, 7days
after 20/40 and 30days after 20/30.
9
Result
OCT(Cirrus HD-OCT)
Macular Thickness
BRVO-Macular edema 8eyes/8patients
BRVO, the mean macular thickness, before surgery
344µm, but decreased after 1day to 265µm, 7days
after 222m, 30days after 197µm
10
Result
Visual acuity (BCVA)
Diabetic macular edema 14eyes/11patients
Diabetic macular edema, mean visual acuity before
surgery was 20/400, but one day after surgery it
improved to 20/80, 7days after 20/50 and 30days
after 20/40.
11
Result
OCT (Cirrus HD-OCT)
Macular Thickness
Diabetic macular edema 14eyes/11patients
Diabatic macular edema, the mean macular
thickness, before surgery was 391µm but after
1day of surgery it decreased to 299µm, 7days
249µm, and 30days 223m.
12
Conclusion
It was concluded that pars plana injection of
the drug during cataract extraction by
phacoemulsification was effective for the
improvement of postoperative visual acuity of
patients with prolonged uveites and with
diabetic/BRVO-associated macular edema.
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