Hormonal Control of Digestion

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Hormonal Control of Digestion
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Gastrin hormone produced by stomach.

• Triggered by entry of food into the stomach, and
  the stretching of the stomach

Gastrin
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Gastrin

• Enters the bloodstream????
• goes back to the stomach affecting the parietal
  cells

Gastrin
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Gastrin

• Promotes the release of HCl , stomach churning

Gastrin
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Cross section of the stomach
these are the folds
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• 2 kinds of Cells
• Parietal Cells
• stimulated from GASTRIN

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• 2 kinds of Cells
• Parietal Cells after stimulation from GASTRIN
  secrete HCl

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Cross section of the stomach
these are the folds
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2 kinds of Cells 2) Chief Cells stimulated by
HCl
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2 kinds of Cells 2) Chief Cells stimulated by
HCl secrete pepsinogen this is an inactive form
of pepsin
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Cross section of the stomach
these are the folds
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Cross section of the stomach
these are the folds
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Secretin hormone produced in cells of the small
intestine

• Triggered by HCl acid in the chyme
• enters bloodstream and stimulates pancreatic
  cells.
• Response Output of sodium bicarbonate buffer.

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Secretin hormone produced in cells of the small
intestine

• ALSO, stimulates the liver to produce bile
• BILE emulsifies FAT

First hormone discovered
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CCK hormone produced in cells of the small
intestine

• Triggered by partially digested protein fat
  that enters the sm. intestine

CCK
CCK
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CCK hormone produced in cells of the small
intestine

• Stimulates Gallbladder contraction to release
  bile
• Stimulates Pancreas to release enzymes
• Reduces appetite

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Enterogastrone

• Hormone produced in small intestine
• Triggered by acid - rich chyme filled with
  lipids.
• Target cells in the stomach and blocks gastrin
• Slows digestion b/c digestion of fats takes more
  time

Entero-gastrone -
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Enterogastrone

• Inhibits peristalsis and acid secretion of the
  stomach
• Slows digestion in the stomach.

Entero-gastrone -