Dermatology%20

1
Dermatology Oral Disease

• Laith Akkash M.D
• Consultant Dermatologist, Dermasurgeon
  Allergist
• Assistant professor of Dermatology
• Jordan University Hospital
• University of Jordan

2

• Dermatology
• Its relationship with oral diseases
• Histology of the Skin
• Histology of the mucous membranes
• Functions of mucous membranes
• Types of mucous membranes in the oral cavity

3
(No Transcript)
4

• Stratified squamous epithelium
• May or may not be keratinized
• Lamina propria is the underlying C.T. layer
• Submucosa
• Salivary glands

5
Oral mucosa can be subdivided into

• 1-Masticatory mucosa keratinized stratified
  squamous epithelium, found on the dorsum of the
  tongue, hard palate and attached gingiva.
• 2- Lining Mucosa non-keratinized stratified
  squamous epithelium, found almost everywhere else
  in the oral cavity
• 3- Specialized mucosa specifically in the
  regions of the taste buds on the dorsum of the
  tongue

6
Relatively common disorders that may affect the
mucous membranes

• 1) Infections
• 2) Bullous diseases
• 3) Connective tissue diseases
• 4) Allergic conditions
• 5) Benign Malignant tumors
• 6) Genodermatosis
• 7) other skin diseases

7
1) Infections

• Viral infections
• - Herpes Simplex
• - Herpes Zoster
• - Hand foot mouth disease
• - Warts HPV
• - HIV- Oral hairy leukoplakia

8
Cold sores
9
(No Transcript)
10
(No Transcript)
11
1ry herpes simplex
12
Oral warts
13
Oral hairy leukoplakia
14
Hand foot mouth disease
15
(No Transcript)
16
(No Transcript)
17
1) Infections contd.

• B) Bacterial
• - 1ry Syphilis
• - 2ry Syphilis
• - Gonococcal pharyngitis Tonsillitis
• - Actinomycosis
• - TB
• - Leprosy

18
1ry syphilitic chancre
19
2ry syphilis mucous patch
20
Gonorrhea
21
Gonoccocal pharyngitis
22
1) Infections contd.

• C) Fungal infections
• - Candidiasis
• - Histoplasmosis

23
Oral Thrush - Candidiasis
24
Relatively common disorders that may affect the
mucous membranes

• 1) Infections
• 2) Bullous diseases
• 3) Connective tissue diseases
• 4) Allergic conditions
• 5) Benign Malignant tumors
• 6) Genodermatosis
• 7) other skin diseases

25
2) Bullous diseases

• Pemphigus vulgaris
• Bullous pemphigoid
• Cicatricial pemphigoid
• Linear IgA disease

26
Pemphigus vulgaris
27
Pemphigus vulgaris
28
Relatively common disorders that may affect the
mucous membranes

• 1) Infections
• 2) Bullous diseases
• 3) Connective tissue diseases
• 4) Allergic conditions
• 5) Benign Malignant tumors
• 6) Genodermatosis
• 7) other skin diseases

29
3) Connective tissue diseases

• Systemic lupus erythematosus
• Progressive systemic scleroderma

30
Systemic Lupus Erythematosus
31
Relatively common disorders that may affect the
mucous membranes

• 1) Infections
• 2) Bullous diseases
• 3) Connective tissue diseases
• 4) Allergic conditions
• 5) Benign Malignant tumors
• 6) Genodermatosis
• 7) other skin diseases

32
4) Allergic conditions

• Fixed drug eruption
• Allergic contact stomatitis
• Angioedema

33
Angioedema
34
Relatively common disorders that may affect the
mucous membranes

• 1) Infections
• 2) Bullous diseases
• 3) Connective tissue diseases
• 4) Allergic conditions
• 5) Benign Malignant tumors
• 6) Genodermatosis
• 7) other skin diseases

35
5) Benign Malignant Tumors

• Benign
• Naevi
• Fibromas
• Granular cell tumor
• Hemangiomas
• Lymphangiomas
• Leiomyomas
• Pyogenic granulomas

• Malignant
• Squamous cell ca.
• Malignant melanoma
• Sarcomas
• Lymphomas

36
SCC lip
37
SCC -Ventral tongue
38
Relatively common disorders that may affect the
mucous membranes

• 1) Infections
• 2) Bullous diseases
• 3) Connective tissue diseases
• 4) Allergic conditions
• 5) Benign Malignant tumors
• 6) Genodermatosis
• 7) other skin diseases

39
6) Genodermatosis

• Epidermolysis Bullosa
• Dariers disease

40
Epidermolysis Bullosa
41
(No Transcript)
42
(No Transcript)
43
Relatively common disorders that may affect the
mucous membranes

• 1) Infections
• 2) Bullous diseases
• 3) Connective tissue diseases
• 4) Allergic conditions
• 5) Benign Malignant tumors
• 6) Genodermatosis
• 7) other skin diseases

44
7) Others

• Lichen Planus
• Behcet Disease
• Aphthous ulcers
• Fordyce disease
• Mucocele
• Angular cheleitis
• White sponge naevus
• Tongue diseases

45
Lichen Planus
46
Oral LP
47
Oral LP
48
Aphthous ulcers
49
Aphthous ulcers
50
Aphthous ulcers
51
(No Transcript)