???? B?????????? - PowerPoint PPT Presentation

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Title:

???? B??????????

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Title: B Author: ldc Last modified by: ldc Created Date: 5/17/2004 3:12:37 PM Document presentation format – PowerPoint PPT presentation

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Title: ???? B??????????


1
???? B??????????
2
????
  • B?????????
  • B1???TI???????
  • ?????????
  • B?????????

3
??B?????????--????
  • B2???TD-Ag???
  • ??1.??Th???
  • 2.?Ig????
  • 3.?????????
  • 4.???????,???????

4
?????????
  • 1.????
  • B2????BCR??TD-Ag??????,???????
  • Iga?Igß??????????,????CD19?CD21??????????

5
(No Transcript)
6
  • 2.????
  • (1)???????????,????,????????MHC-?????????B?????
  • (2)B???Th2???????B??????????? ???CD40-CD40L

7
(No Transcript)
8
Th???B???????
  • B???Th?????
  • 1.????????,B???????? ??Th??
  • 2.B???Th??????????B7
  • Th???B?????
  • 1.???Th???B??????????? CD40LCD40
  • 2.Th????????(IL-4?IL-5?IL-6?IL-10?IL-13)??B???????
    ?

9
(No Transcript)
10
(No Transcript)
11
(No Transcript)
12
B????????????
  • ??????B??????????
  • ????????????????????????
  • ?????????????????????

13
  • ????????Ig??????
  • 1)???????????????????????????????????????,??????I
    gV?????
  • 2)?????????????????????????
  • ???????Ig?????????B?????

14
(No Transcript)
15
(No Transcript)
16
(No Transcript)
17
  • 3.????????????????
  • (1)????
  • (2)????
  • (3)????
  • (4)ADCC
  • (5)??????
  • (6)?????

18
?? B1???TI???????
  • ??1.??Th???
  • 2.???IgM???,?Ig????
  • 3.?????????
  • 4.???????,???????

19
(?) B1???TI-1???????
  • TI-1??????B?????
  • ????TI-1???????B?????????
  • ???TI-1?????????BCR?B????
  • B???TI-1??????????????????????????,??TD????????
  • TI-1?????????Ig???????????????B?????

20
(No Transcript)
21
(?) B1???TI-2???????
  • TI-2?????????????????,?????????
  • ???????B1??
  • ??????TI-1????B???????????
  • B???TI-2??????????????

22
???????????
  • ____________________________________________
  • ???? ????
  • ____________________________________________
  • ??? ? ?
  • ???? ? ?
  • ???? ? ?
  • Ab?? ???IgM ???IgG
  • Ab?? ? ?
  • ??? ? ?
  • ____________________________________________

23
(No Transcript)
24
  • ?????????????

25
?? B?????????
  • ????
  • ????

26
? ?
  • B?????????
  • B1???TI???????
  • ?????????
  • B?????????
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