Understanding Reproduction and Chromosomes

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Understanding Reproduction and Chromosomes

• Carolina Biological Supply
• 251007A
• 179.95

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Kit includes 4 activities

• Activity 1 Asexual Reproduction
• Activity 2 Chromosomes and Karyotyping
• Activity 3 Sexual Reproduction
• Activity 4 Genetic Disorders

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Prior Knowledge

• Students must have strong understanding of
  meiosis and DNA prior to completing this lab.
• Review vocabulary terms
• Diploid
• Haploid
• Crossing over
• Homologous chromosomes
• Gametes
• Gene
• fertilization

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Prior Knowledge Continued-a review of meiosis
stages is also suggested

• Overview of meiosis

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Learning Goals

• Review chromosome structure and meiosis
• Be introduced to karyotyping and genetic
  disorders
• Compare asexual and sexual reproduction.

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Materials (for activities 2,3, and 4)

• 15 magnetic boards
• 15 sets of human chromosome magnets
• 16 plastic bags
• Prepared microscope slides of human male and
  female chromosomes
• Reproducible student guide including a chromosome
  key and a karyotype of a normal human male.

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Overview of Activities

• Activity 2 Chromosomes and Karyotyping
• Students look at prepared slides of normal male
  and female chromosomes and are asked to make
  observations.
• Class is divided into 10 groups. Half of the
  groups get a bag of female chromosomes and the
  other half get the male chromosmes.
• Students are asked to examine chromosomes and
  note general characteristics and then they are to
  come up with a way to organize the chromosmes.
• It is not required that students come up with an
  accurate karyotype, but they should become
  familiar with chromosome banding and pairing.

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Overview of activities

• Activity 3 Sexual Reproduction
• This activity simulates human reproduction.
• The male karyotype groups pair up with a female
  karyotype group from activity 2.
• Groups having male and female karyotypes work
  together to find ways in which a zygote could be
  formed from the chromosomes present in two normal
  human gametes.

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Overview of Activities

• Activity 4 genetic disorders
• Parent karyotypes made in activity 2 will be
  used.
• Each group gets a chromosome packet containing a
  karyotype with a specific genetic disorder.
• After the zygote is assembled, students compare
  it with the two normal parent karyotypes and
  discover ways in which common genetic disorders
  are formed.

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• Today we are going to look at activities 2 and 4.
• I need you to work in groups of 3 or 4 making 5
  groups total.
• One or two people will receive the male
  chromosmes and the other one to two people will
  receive the female chromosomes.
• After assembling the parent karyotypes each group
  will receive a separate bag of chromosomes
  representing a zygote with a specific genetic
  disorder.