Drugs and Medicines

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Drugs and Medicines
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Love and Depression
Chemistry in Action
Scientists have known for a century about
phenylethylamine, and in recent times some have
held the chemical responsible for our feelings
of love'.
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Is Chocolate is high in caffeine? The amount of
caffeine in a piece of chocolate candy is
significantly lower than that in coffee, tea or
cola drinks. For instance, a 5 oz cup of instant
coffee has between 40 and 108 mg of caffeine,
while a one oz milk chocolate bar contains only
6 mg and many confectionery items have no
caffeine at all.

• Q. What is the level of cholesterol in a 1.65 oz.
  bar of milk chocolate?
• The American Heart Association recommends that
  daily cholesterol
• intake not exceed 300 mg. A chocolate bar is
  actually low in
• cholesterol. A 1.65 oz. bar contains only 12 mg!
  A one oz piece of
• cheddar cheese contains 30 mg of cholesterol -
  more than double
• the amount found in a chocolate bar.

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These are the two Americas. No other line you
can draw is as trenchant as this. On one
side, people of normal human appetities for food
and sex and creature comforts on the other,
those who crave only the roar and crackle of
their own neurons, whipped in a frenzy of
synthetic euphoria. Newsweek Nov. 28, 1988, p
64
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Analgesics Reduce pain Antipyretic Reduce fever
Aspirin
prostaglandins
Analgesics Reduce pain Antipyretic Reduce fever
Tylenol
More toxic Doesnt cause Reyes syndrome
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Ibuprofen
Safer than aspirin Much safer than tylenol
All of the analgesics are less toxic than
caffeine
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Oil of wintergreen Based on aspirin
structure Topical ointment
Capsaicin Hot stuff in pepper A potent
analgesic for arthritis
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Ciprofloxacin
Cipro
Antibacterial
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What are the symptoms of anthrax? Symptoms of
disease vary depending on how the disease was
contracted,but symptoms usually occur within 7
days. Cutaneous Most (about 95) anthrax
infections occur when the bacterium enters a cut
or abrasion on the skin, such as when handling
contaminated wool, hides, leather or hair
products (especially goat hair) of infected
animals. Skin infection begins as araised itchy
bump that resembles an insect bite but within 1-2
days develops into a vesicle and then a painless
ulcer, usually 1-3 cm in diameter, with a
characteristic black necrotic (dying) area in
the center.Lymph glands in the adjacent area may
swell. About 20 of untreated cases of cutaneous
anthrax will result in death. Deaths are rare
with appropriate antimicrobial therapy.

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Inhalation Initial symptoms may resemble a
common cold. After several days, the symptoms may
progress to severe breathing problems and shock.
Inhalation anthrax is usually fatal.
Intestinal The intestinal disease form of
anthrax may follow the consumption of
contaminated meat and is characterized by an
acute inflammation of the intestina l tract.
Initial signs of nausea, loss of appetite,
vomiting, fever are followed by abdominal pain,
vomiting of blood, and severe diarrhea.
Intestinal anthrax results in death in 25 to
60 of cases
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Antiviral Drugs
Acyclovir
AZT
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Sex Hormones
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RU-486
The medication "mifepristone" was invented in
France by Dr. Etienne-Emile Baulieu in 1980.
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Anticancer Drugs
Alkylating Agents - add alkyl groups To DNA . .
. Hopefully causing cell death.
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Mustard Gases
Gassed, John Singer Sargent
(1919)
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Note similarity to cyclophosphamide
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Antimetabolites . . . Compounds that Mimic and
trick other compounds
Folic acid
Methotrexate
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Alcohol
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The effects of alcohol on sexual behavior has
often been cited . . . . as an
ice-breaker Candy is dandy, but liquor is
quicker Ogden Nash
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In Macbeth Describing the effects of alcohol,
the porter states Lechery, sir, it
provokes, and unprovokes It provokes the
desire, but takes away the performance.
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What more fiendish proof of cosmic
irresponsibility than a Nature which, having
invented sex as a way to mix genes, then permits
to arise, amid all its perfumed and hypnotic
inducements to mate, a tireless tribe of
spirochetes and viruses that torture and kill us
for following orders?
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Morphine one of the best of all pain killing drugs
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Drug discovery based on Natural Products
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Cocaine
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Hallucinogenic Drugs
Mescalin
Ectasy
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Antidepressants

• Change in appetite
• Change in sleep
• Psychomotor retardation
• Loss of interest
• Decrease sexual drive
• Increased fatigue
• Guilt feelings
• Impaired concentration
• Ideas of suicide

Prozac
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