Figure 13.6 Bacteriophage T4-overview

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Figure 13.6 Bacteriophage T4-overview
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Viral Replication

• Dependent on hosts organelles and enzymes to
  produce new virions
• Lytic replication
• Replication cycle usually results in death and
  lysis of host cell
• Stages of lytic replication cycle
• Attachment
• Entry
• Synthesis
• Assembly
• Release

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Figure 13.8 The lytic replication cycle in
bacteriophages-overview
Attachment
Bacteriophagegenome
Entry
Tail sheath
Outer membrane
Peptidoglycan
Cytoplasmicmembrane
Bacterialchromosome
Entry
Attachment
Phage DNA
Lytic replicationcycle of bacteriophage
Bacterialchromosomedegraded
Release
Synthesis
Phage proteins
Assembly
Assembly
Base
Tail
Sheath
DNA
Tail fibers
Mature virion
Capsid
Mature head
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Viral Replication
ANIMATION Viral Replication Overview
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Figure 13.9 Pattern of virion abundance in lytic
cycle
Burst size
Number of infective virionsin medium (log scale)
Release of virions by lysis
Entry
Synthesis and assembly
Time (minutes)
Attachment
Burst time
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Viral Replication
ANIMATION Viral Replication Virulent
Bacteriophages
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