School of Medicine Shared Resource Facilities

1
School of Medicine Shared Resource Facilities

• The School of Medicine provides direct support
  and oversight to 21 SOM shared resource
  facilities.
• Their purpose is to provide investigators within
  the Penn community access to scientific services
  widely required in the conduct of biomedical
  research but which are too costly for individual
  investigators or departments to bear.
• Oversight is provided by the School of Medicine
  Research Core Facilities Committee, which is led
  by an Associate Dean for Research Core Facilities.

2
Contributions of PSOM to Cores
FY07 FY08 FY09 FY10 FY11 FY12
Investments via Core Committee 250,000 250,000 250,000 250,000 250,000 250,000
Other Core Investments 700,000 300,000 312,428 420,585 420,585 637,095
PSOM Support for Renovations 1,493,448 445,000
PSOM Support for Equipment 328,296 413,890 119,702 1,956,875
Total Expenditures 2,443,448 1,323,296 562,428 1,084,475 790,287 2,843,970
3
Reporting Structure
4
Research Core Facilities Committee

• 15 member committee representing various
  departments and areas of science
• Meets once a month
• Conducts reviews of core performance
• Evaluates core equipment and financial requests
• Requests an in-depth annual report every March
• Considers potential cores that should be developed

5
Cores Committee Members
Perelman School of Medicine
CHOP

• Morrie Birnbaum, IDOM
• Michael Feldman, Path Lab Med
• Yale Goldman, Physiology
• Michael Granato, CDB
• Kate Nathanson, Medicine
• Nancy Speck, CDB
• Bob Vonderheide, Medicine
• John Wherry, Microbiology
• Admin Support Dorothy Leung

Tom Curran
Wistar
Bill Wunner
Abramson Cancer Center
Barbara Vance
Ex Officios
Kathy Bramwell, Finance Susan Passante,
EVD/CSO Brian Wells, IT Research Computing
6
Reviews and Requests Process

• Among the key considerations of the review
  process

Consider ways to provide additional support
Examine how well the Core is providingthe service
Determine whether the Service is affordable to
Penn PIs
7
Biomedical Core Resources
Current Medical School Cores
Cores in Development
Behavioral Testing Unit Cell Center Services Cell
Center Stockroom Clinical Cell and Vaccine
Production Facility Clinical Research Computing
Unit Confocal Core DNA Sequencing Facility
Gene Targeting Service Electron Microscopy
Core Flow Cytometry and Cell Sorting Research
Lab Human Immunology Core Investigational Drug
Service Molecular Profiling Core Next Generation
Sequencing Proteomics and Systems Biology
Core Research Instrumentation Shop Small Animal
Imaging Facility Core Stem Cell and Xenograft
Core Transgenic and Chimeric Mouse
Core Translational Core Laboratory Vector Core
Bio-banking Bioinformatics High throughout
screening
New
Under review
8
www.med.upenn.edu/cores/
9
(No Transcript)
10
Considerations in using Cores for large projects

• Is there sufficient money budgeted?
• Should there be funds for infrastructure?
• Does the Core have sufficient capacity?
• Can the Core supply necessary supporting material
  for grant application?
• Is the charge-back scheme compliant?

11
OMB Circular A-21
12
OMB Circular A-21
13
(No Transcript)