HIV/AIDs Possible Treatments (Stem cell)

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HIV/AIDsPossible Treatments (Stem cell)
Garrett Reid Block 3 (Jensen)
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The disease

• The Immune System (Immunodeficiency)
• Specifically Helper T-Cells, Macrophages, and
  dendritic cells
• AIDS (Not HIV) is what leads to death
• Causes a total shut down of the bodys immune
  system
• AIDS doesnt kill you
• HIV causes symptoms
• Fever, rash, muscles aches and swollen lymph
  nodes and glands
• How many people in the US and/or world
• Estimates vary, 1,000,000 in US alone
• 31.3 Million adults and 2.1 million children
  World Wide
• There is an upside

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Normally

• In the healthy body
• When an antigen enters the body helper T-Cells
  bind to the MHCs of the foreign body signaling
  its destruction
• After this, the body is programmed towards the
  antigens destruction should it enter the body
  again.

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Best current treatment

• Because HIV/AIDS can mutate and become immune to
  treatments at an accelerated pace, most
  treatments involve a chemical cocktail
• 47 (give or take) different medications
• Not a simple method
• This treatment carries with it many complications
• Patients play the side effect game
• The chemical compounds are a burden on the body
• Extremely large structures
• Designed now so the body to not be able to break
  it down
• Intended to extend the length of treatment

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Stem Cell Treatment

• HIV has been found to cause an associated form of
  Lymphoma (both Hodgkin's and non-Hodgkins)
• Treatments pertaining to this include a full
  irradiation of the body and using a stem
  cell/bone marrow transplant to help the body
  recover.
• Stem Cells being used in these treatments are
  Peripheral blood stem cells
• Also, studies have shown that some people have a
  protein aimed towards slowing the spread of HIV,
  what doctors have begun to do