Protein Structure

1
Protein Structure

• Primary - sequence of amino acids
• Secondary folding into pleated sheets or alpha
  helix
• Tertiary 3-D structure, completely folded
• Most proteins stop here
• Quaternary interaction of several protein
  molecules
• Hemoglobin

2
2-4 Chemical Reactions and Enzymes

• Enzymes
• biological catalysts
• Speed up reactions
• Without them reactions would occur too slow for
  life
• Lower the activation energy

3
Enzymes

• Enzymes provide a site where substrates can be
  brought together Active Site (tertiary)
• The fit is like a lock and key

4
Enzyme Regulation

• Work best at a particular pH
• Digestion enzyme
• Affected by changes in temperature
• Denaturization
• Concentration

5
p. 51

• Suggest an explanation for the change at 40 sec.
  in the control.
• How does the base affect the enzyme?
• How does the acid effect the enzyme?