Phys of Osseous Tissue

1
Phys of Osseous Tissue

• Mineral Deposition crystallization of Ca2, P
  and other ions to form bone
• Mineral resorption dissolving of bone caused by
  an enzyme acid phosphates that is produced by
  osteoclasts
• Ca2 is used in many body processes and must be
  regulated to maintain normal body function

2
Phys of Osseous Tissue

• Bones act as a storage center for key minerals
  Ca2 being one of most important
• Bones have two Ca2 reserves 1) stable part of
  bone hard to release into blood, 2) about 1 of
  bone mass that is released or absorbed with need
• Hypocalcemia low blood Ca2 leads to tremors and
  spasms

3
Phys of Osseous Tissue

• Hypercalcemia high levels of Ca2 in blood leads
  to muscle weakness, emotional disturbances, Code
  Blue
• Calcitriol is a form of Vit D that acts as a
  hormone to raise Ca2 absorption in SI and
  increase resorption
• Calcitonin is produced by the thyroid gland to
  inhibit resorption and promote deposition

4
Phys of Osseous Tissue

• Parathyroid Hormone (PTH) produced by the
  parathyroid to increase the resorption
• Draw up a negative feedback loop for Ca2 levels
  in the blood include the three acting hormones,
  hypo and hypercalcemia and resorption and
  deposition