Resporite

1
Resporite
Little Patients, Big Demands

• Elisa Fung
• Lindsay Kugler
• BeiXian Tang
• Gabriela Vargas

2
Motivation

• Mortality rate for children under the age of 5 in
  Africa is double that of the rest of the
  developing world
• 166 deaths per 1000 children
• Respiratory distress syndrome (RDS) is the
  leading cause of death for underweight infants
• Can be treated with ventilators
• Design a reliable, easy-to-use, and low-cost
  ventilator for use in the developing world

3
Design
Power source
Warning system/ system shut down
Valve 2 Regulates pressure to 5cm H2O
Pressure, humidity, temperature sensors
Tire pump
Nasal cannulae
Pressure storage chamber
Valve 1 Regulates pressure to 5psi
Bike pump
Humidifier Humidifies and filters air
Bubbling indicates system is working
4
Design
5
Midterm Goals

• Establish connections between components
• Test components individually and as a system
• Determine length of time to fill empty chamber
• Set outgoing air pressure to 5-7 cmH2O
• Determine flow rate
• Humidify and filter air

6
Design Process

• Component 1 Air compressor
• Attempt 1 Mattress pump
• Attempt 2 Tire pump
• Component 2 Pressure storage chamber
• Component 3 Valves
• Valve 1 (0-150 psi)
• Valve 2 (0-2 psi)
• Component 4 Humidifier

7
Testing Pressure Storage Chamber

• Purpose
• Determine the time required to fill the pressure
  storage chamber.
• Results
• Exponential relationship between time and
  pressure

8
Testing Regulating Pressure

• Purpose
• Determine if desired output pressure (5-7 cmH2O,
  or 0.07-0.10 psi)
• Results
• Desired pressure achieved

5 cmH2O
9
Testing Pressure Duration

• Purpose
• Determine how long constant pressure will be
  observed at valve output with varying chamber
  pressure
• Results
• Determined that optimal starting pressure is 60
  psi
• Pressure in chamber does not last as long as
  desired

10
Testing Humidifier

• Purpose
• Determine effects of humidifier on system
• Results
• Increases amount of time chamber can sustain
  desired pressure
• Air is humidified

11
Testing Flow Rate

• Purpose
• Determine flow rate at 5-7 cmH2O
• Results
• Flow rate approximately 2.5 L/min
• Ideal flow rate is 5 L/min

Water (mL) Time (s)
100 2.07
200 4.34
300 7.13
400 9.88
500 12.34
12
Conclusion

• Macroscale Prototype
• Major components of system connected
• Pressure of 5-7 cmH2O achieved
• Air flow rate of 2.5 L/min achieved
• Humidified and purified air

13
Future Work

• Optimize flow rate for macroscale system
• Incorporate temperature parameters
• Backup system bike pump, battery
• Microscale device to optimize current ventilator
  system
• Electrical feedback system using LEDs and buzzer

14
Acknowledgments

• Dr. Gordana Vunjak-Novakovic
• Dr. Samuel Sia
• Dr. Helen Towers
• Dr. Jen-Tien Wung
• Yukkee Cheung
• Keith Yeager
• Sean Burgess
• Rob Maidhof
• Jonathan Belmont

15
Questions

• ?