Power Point

1
????
2
?????????????
3
??????????
4
???????????

• ????????863????
• ?????????
• 1996?7?????????
• 1997?9??????????
• ???FDA(??????????)??
• ?????
• 2004?????????????????
• 2007????????????????

???????????ZL931.18918.1 ???????????5.6687.46
9
5
??????????
??????????? , ???????????? ????????????
??????????
6
2008????????,?????????????????????????????????????
,???????????
????
??????
7
????????????
8
?????????

• ?????????????????
• ???????????????????????????????????????(?????)????
  ?,???????????,??????????????? ????????????????????
  ??????,????????????????100??,??????????????,??????
  ???????????

9
????????

• ???????????????????,??????????????????????????????
  ?????????
• ????1983????????MRI(????)?????
  1984????MRI??????1989?,????MRI????,?????
• ?????????????????????????,???????????????,??????
  ????????? ????????,????????,????????????,???????
  ??????70,????????????????????

10
?????????

• ???????????????????????????????????,??????????????
  ??????????????????????????????????????????????????
  ???(???)?????????????????????
• ?????????????????????????,????????????????,????,?
  ?????????,????????????????(???????????)????,????
• ????????????
• ????????,????????,???????
• ??????,??????,?????????,?????,???,??????????? ?
• ??????????????
• ?????????????????

11
???????
??????????????????????????????????,???????????
????????????,??????????????????

• ????
• ??? ??????,?????
• ?????????,??
• ???????,??
• ?? ???????????????,?????

12
???????
??????????????????????????????????????? ?????????
???????????????,???????????,???????????????,??????
?????,??????1000?????????????????????????????,????
????????2003?8??2004?6????????????????SARS????????
???,???????
13
???????

• ????????????,?????,???

• ??????????????????,??

14
???????

• ??????????,????????

• ???????????,???,??,???????,????

15
???????

• ?????????????????????

• ?????????????

16
Advances in magnetic therapy basic and clinical
research????????????????
17
????

• ??(Magnetic therapy)???????????????????????,??????
  ??????????????
• ???????????????(non-invasive), ?????(no health
  risk), ????(no side-effects)???????????(non-medica
  l method for the treatment of discomfort )
• ???????????????????????????,?????????2000???????
  
• ?20??,????????????????????,????????????,??????????
  ?????????????????????????????,??????????,???????
  ?????????

18
?????????

• ?????????????,???????????,??????????????????????
  ?????(static magnetic field,SMF)?????(dynamic
  magnetic field,DMF)???,??????????????,????????,???
  ?????????????????????
• ??????????????????,??????(SI)????????SI?,?????????
  ???(T),???????,????????????(Gs),?????????1T10000
  Gs??????????mT???????,1mT10Gs

19
??????
Michael McLean,et al. Static Magnetic Fields for
the Treatment of Pain. Epilepsy Behavior 2,
S74S80 (2001)
20
????(Rotating permanent magnetic field)

• ?????????????????,????????????????????
  ????????????,????????????????????

21
????????????
22
???????

• ???????????????,????????????

23
SMF?RMF??????

• ????????????????????????????????

24
???????????

• ???????????????????,???????????????????????????
• -????????????(electromagnetic organism )
• -4000?????? ????????10?,??????????????
• -??????????????????????????????????????????
  ???????????
• -??????????????????????
• -???? (fluid retention)
• -??????????
• -?????(endorphins )
• -????(relaxation of muscles)
• - ?????????????(acupoints)

25
??????

• ????????????,???????????????????????,??????,??????
  ?????????
• People with implantable medical devices
  such as heart pacemakers, defibrillators, insulin
  pumps, or hepatic artery infusion pumps should
  avoid exposure to magnets, as magnets may affect
  the functioning of some equipment
• ?????????????????????????????????????????????????
  ????????????????????,?????????????????
• Some publications discourage the use of
  static magnets or electromagnetic field therapy
  during pregnancy or in people with myasthenia
  gravis or bleeding disorders, and suggest that
  magnets may cause dizziness, nausea, or prolong
  poor wound healing or bleeding. Scientific
  research is limited in these areas
• ?????????????,???????????????????????
• Magnet therapy is not advised as the sole
  treatment for potentially serious medical
  conditions, and should not delay the time to
  diagnosis or treatment with more proven methods

??FDA????lt4TWHO????lt2T
26
SMF??????

• ?????????????????????,???????????????????????,????
  ?????????????

• Xu???????????????,??luorescence
  epi-illumination????????????50Hz??????????????????
  ????????????0.3,1 ? 10 mT ,???????? 50-Hz EMF 0.3
  ? 1 mT,??????10???????,?10mT?????,????????????????
  ????????????????1mT?????,????????????????????????
  ??????????,?????????????

Shenzhi Xu, Hideyuki Okano , Chiyoji Ohkubo.
Acute effects of whole-body exposure to static
magnetic fields and 50-Hz electromagnetic fields
on muscle microcirculation in anesthetized mice.
Bioelectrochemistry 53 2000 127135
27
SMF??????

• Okano??????(SMF)??????????????????????????????????
  ?????????????(microphotoelectric
  plethysmography)??????????????????????1mT,??10????
  ?????,?SMF?????????????????SMF?????????????????SMF
  ?????????????????SMF?????????????????SMF????????,S
  MF????????????,??????????????????????????,??????
  ???????????????????,?????????????

Hideyuki Okano , Juraj Gmitrov , Chiyoji Ohkubo
.Biphasic effects of static magnetic fields on
cutaneous microcirculation in rabbits.
Bioelectromagnetics 20161-171, 1999
28
SMF???????????????

• Takeshiged?????,????????????????????????????,?????
  ???????????????????????????????,??????????????????
  ??????????????

C. Takeshige, M. Sato, Comparisons of pain relief
mechanisms between needling to the muscles,
static magnetic field, external qigong and
needling to the acupuncture point, Acupunct.
Electro-Ther. Res. 21 1996 119131.
29
???????

• 2003?,??Virginia ??????????Cassandra Morris
  ????Thomas Skalak ???????????Experimental
  Biology 2003?,???????SMF?????????????????????????
  ????????? spinotrapezius ??????,??SMF(700G,15??)??
  ??????????
• ????,???????????????????????????????????,?SMF?????
  ??????????????????,?SMF?????SMF?????????????????
  ?????????SMF????????????,????????SMF?????????(???
  ???????????????????)????????

30
Virginia ???????

• ?Ann Taylor Gill ???????2002????????SMF?????(fibro
  myalgia )?????????????,????????NIH???????94?????4?
  ,??????????????????????????,?????????,????????????
  ????????,????????????????,??SMF??????????????????
• ??????NIH??????,Jeremy B. Tuttle
  ?????SMF???????????(neuroblastoma
  cells)12600??????????????,???100????????SMF???,??1
  00????????????????????

31
SMF??????????

• Okano??????SMF???????????????????????,??????1mT,??
  ???30?????????????????,???????????NIC??????,??????
  ???????????????????L-NAME????????????????(1)SMF?N
  IC???????????????(2)?L-NAME??????????????????????
  ?????SMF?????????????????????????????

Hideyuki Okano and Chiyoji Ohkubo. Modulatory
Effects of Static Magnetic Fields on Blood
Pressure in Rabbits. Bioelectromagnetics
22408418 (2001)
32
SMF???????????

• 500-600Gs?SMF???????????????

Martha R Hinman. Comparative effect of positive
and negative static magnetic fields on heart rate
and blood pressure in healthy adults.Clin
Rehabil.2002 16 669
33
SMF???????

• ??Kyoto University?Yan?????????????????,??12?SMF??
  ?????????????????????,????????????????????????????
  ???????????????????????,12????????????????????????

Q.C. Yan, N. Tomita, Y. Ikada. Effects of static
magnetic field on bone formation of rat femurs.
Medical Engineering Physics 20 (1998) 397402
34
RPMF???????

• ???????????????????,??????????????(BAP)
  ?????????????(DPD) ???,???????????????????????????
  ??????????,???????(120??,15?),???????????BAP
  ??????,??DPD ???

??,???.???????????????????????.???????????2004 ?9
??26 ??9 ?. Bioelectromagnetics 2719, 2006.
35
SMF???????

• ??Kinki University?????????Norimasa
  Taniguchi??SD???????,??Mycobacterium
  butyrium????????????,??????SMF??????????????12?,??
  ????20-80mT????????????????????24h????????????????
  (??????????)????(BMD)?????,SMF???????????24h?????B
  MD????????,???????????????????????????,??SMF??????
  ??????????????????

Norimasa Taniguchi.et al. Study on Application of
Static Magnetic Field for Adjuvant Arthritis
Rats. eCAM 2004
36
SMF???????????

• Tim Harlow???RCT?????12??SMG??(??)?194???45-80????
  ??????????,?????????????????(WOMAC A)?????Pain
  from osteoarthritis of the hip and knee decreases
  when wearing magnetic bracelets. It is uncertain
  whether this response is due to specific or
  non-specific (placebo) effects

Tim Harlow,et al. Randomised controlled trial of
magnetic bracelets for relieving pain in
osteoarthritis of the hip and knee. BMJ
200432914504
37
????????

• Daisuke?????????????Wingate????????????????????,??
  ???????????????????(??????)
• ???????RMF??????????????????,??RCSMF??????????????
  ?????, ?????????????????

International Journal of sports and health
science.2,205-210,2004 ?????????????????????,????
??,100022618 (2005)
38
RPMF???????????????
P0.011
??,?RPMF?????????????????,???
39
SMF?LBP???RCT??

• Objective To investigate the potential
  usefulness of static magnetic field therapy in
  the relief of CLBP.
• Design A prospective, blinded, randomised,
  controlled clinical trial
• Subjects Twelve CLBP patients (symptoms for more
  than 3 months)
• Interventions A belt (???)containing two small
  Neomax disc magnets (either 1.20 0.05 T in the
  active or 0.5 0.05 T in the inactive group) was
  given to each
• patient. This was applied continually for the 4
  weeks of the trial.
• Results Ten subjects completed the study. VAS
  scores showed a strong trend (p 0.05) towards a
  decrease in pain in the active magnet group. The
  results support a larger scale study of static
  magnetic field application in chronic low back
  pain.

J. Langford, P.W. McCarthy. Randomised controlled
clinical trial of magnet use in chronic low back
pain a pilot study. Clinical Chiropractic (2005)
8, 1319
40
?????????

• 40?????????????,????SMF,????????,???????SMF???????
  ?????,130mT,3??
• ????????????????????,??????????????1??????SMF????
  ???????

The Pain Clinic Volume 16, Number 2 / June, 2004
41
Thank You